The ins and outs of E-cadherin trafficking

The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

2000 • 3,504 citations

The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells

2000 • 2,569 citations

Membrane Fusion

1990 • 2,458 citations

Convergence of Wnt, ß-Catenin, and Cadherin Pathways

2004 • 2,451 citations

The Mechanisms of Vesicle Budding and Fusion

2004 • 1,738 citations

The snail superfamily of zinc-finger transcription factors

2002 • 1,665 citations

The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion

2001 • 1,351 citations

Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

2004 • 1,270 citations

Membrane Fusion

2003 • 1,265 citations

Regulated transport of the glucose transporter GLUT4

2002 • 1,154 citations

Signal transduction and endocytosis: close encounters of many kinds

2002 • 820 citations

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

2002 • 817 citations

MOLECULAR AND FUNCTIONAL ANALYSIS OF CADHERIN-BASED ADHERENS JUNCTIONS

1997 • 800 citations

Rho family proteins: coordinating cell responses

2001 • 763 citations

A core function for p120-catenin in cadherin turnover

2003 • 714 citations

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

2002 • 676 citations

FGF Signaling Regulates Mesoderm Cell Fate Specification and Morphogenetic Movement at the Primitive Streak

2001 • 675 citations

Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly.

1994 • 633 citations

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion

2003 • 631 citations

The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis

1999 • 623 citations

Lipid Rafts and Caveolae as Portals for Endocytosis: New Insights and Common Mechanisms

2003 • 589 citations

The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn

1998 • 566 citations

Recycling of E-Cadherin

1999 • 538 citations

Adaptor-related proteins

2001 • 531 citations

Mechanisms of Epithelial Cell–Cell Adhesion and Cell Compaction Revealed by High-resolution Tracking of E-Cadherin– Green Fluorescent Protein

1998 • 527 citations

Sec6/8 Complex Is Recruited to Cell–Cell Contacts and Specifies Transport Vesicle Delivery to the Basal-Lateral Membrane in Epithelial Cells

1998 • 523 citations

A novel role for p120 catenin in E-cadherin function

2002 • 514 citations

Role of IQGAP1, a Target of the Small GTPases Cdc42 and Rac1, in Regulation of E-Cadherin- Mediated Cell-Cell Adhesion

1998 • 505 citations

A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor

2002 • 498 citations

Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factors

2000 • 468 citations

Autoregulation of E-cadherin expression by cadherin–cadherin interactions

2003 • 462 citations

Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling

1997 • 448 citations

A New Role for E12/E47 in the Repression ofE-cadherin Expression and Epithelial-Mesenchymal Transitions

2001 • 439 citations

Rho-family GTPases in cadherin-mediated cell — cell adhesion

2001 • 424 citations

Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells

2003 • 399 citations

Sorting out the cellular functions of sorting nexins

2002 • 394 citations

Membrane traffic in polarized epithelial cells

2000 • 384 citations

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex

2003 • 378 citations

Endocytosis of Epithelial Apical Junctional Proteins by a Clathrin-mediated Pathway into a Unique Storage Compartment

2003 • 372 citations

Molecular linkage between cadherins and actin filaments in cell—cell adherens junctions

1992 • 359 citations

Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling

2002 • 351 citations

Tyrosine phosphorylation and cadherin/catenin function

1997 • 318 citations

ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly

2002 • 298 citations

Coupling Assembly of the E-Cadherin/β-Catenin Complex to Efficient Endoplasmic Reticulum Exit and Basal-lateral Membrane Targeting of E-Cadherin in Polarized MDCK Cells

1999 • 289 citations

Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions

2002 • 270 citations

The ins and outs of aquaporin-2 trafficking

2003 • 266 citations

Regulation of Rho GTPases by p120-catenin

2001 • 265 citations

p120 catenin associates with kinesin and facilitates the transport of cadherin–catenin complexes to intercellular junctions

2003 • 251 citations

Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network

2004 • 244 citations

Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 γ–σ1 and AP-3 δ–σ3 hemicomplexes

2003 • 236 citations

Differential localization of syntaxin isoforms in polarized Madin-Darby canine kidney cells.

1996 • 232 citations

Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells

2003 • 213 citations

RAC1 Regulates Adherens Junctions through Endocytosis of E-Cadherin

2001 • 198 citations

Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells – regulation by Rho, Rac and Rab small G proteins

1999 • 191 citations

Mechanism of recruiting Sec6/8 (exocyst) complex to the apical junctional complex during polarization of epithelial cells

2004 • 186 citations

Alsin Is a Rab5 and Rac1 Guanine Nucleotide Exchange Factor

2004 • 181 citations

Characterization of E-cadherin Endocytosis in Isolated MCF-7 and Chinese Hamster Ovary Cells

2003 • 178 citations

Endocytosis of junctional cadherins in bovine kidney epithelial (MDBK) cells cultured in low Ca2+ ion medium.

1991 • 173 citations

A Dileucine Motif Targets E-cadherin to the Basolateral Cell Surface in Madin-Darby Canine Kidney and LLC-PK1 Epithelial Cells

2001 • 172 citations

Ezrin Regulates E-Cadherin-dependent Adherens Junction Assembly through Rac1 Activation

2003 • 161 citations

Activation of the Small GTPase Rac Is Sufficient to Disrupt Cadherin-dependent Cell-Cell Adhesion in Normal Human Keratinocytes

2000 • 158 citations

PKCepsilon controls the traffic of beta1 integrins in motile cells

2002 • 156 citations

Characterization of the Role of Cadherin in Regulating Cell Adhesion during Sea Urchin Development

1997 • 154 citations

Identification of Src Phosphorylation Sites in the Catenin p120

2001 • 142 citations

PDGF, CSF-1, and EGF induce tyrosine phosphorylation of p120, a pp60src transformation-associated substrate.

1991 • 130 citations

Compromised Cytoarchitecture and Polarized Trafficking in Autosomal Dominant Polycystic Kidney Disease Cells

2000 • 129 citations

A Novel Interaction between Kinesin and p120 Modulates p120 Localization and Function

2004 • 125 citations

The cadherin superfamily

2001 • 122 citations

N-cadherin-Catenin Complexes Form Prior to Cleavage of the Proregion and Transport to the Plasma Membrane

2003 • 120 citations

Human Homolog of Disc-large Is Required for Adherens Junction Assembly and Differentiation of Human Intestinal Epithelial Cells

2004 • 119 citations

Protein kinase C regulates endocytosis and recycling of E-cadherin

2002 • 116 citations

EGFR signaling to p120-catenin through phosphorylation at Y228

2004 • 99 citations

The FAM Deubiquitylating Enzyme Localizes to Multiple Points of Protein Trafficking in Epithelia, where It Associates with E-cadherin and β-catenin

2004 • 81 citations

Dominant-negative mutant of BIG2, an ARF–guanine nucleotide exchange factor, specifically affects membrane trafficking from the trans-Golgi network through inhibiting membrane association of AP-1 and GGA coat proteins

2002 • 78 citations

p120 Catenin Associates with Microtubules

2004 • 71 citations

Proprotein cleavage of E‐cadherin by furin in baculovirus over‐expression system: potential role of other convertases in mammalian cells

1998 • 70 citations

Breaking into the epithelial apical–junctional complex — news from pathogen hackers

2003 • 69 citations

The role of cadherin endocytosis in endothelial barrier regulation: involvement of protein kinase C and actin-cadherin interactions.

1998 • 65 citations

Contextual Binding of p120 to E-cadherin at the Basolateral Plasma Membrane in Polarized Epithelia

2003 • 60 citations

Presenilin 1 is involved in maturation and trafficking of N‐cadherin to the plasma membrane

2003 • 46 citations

Dynamin-dependent endocytosis is necessary for convergent-extension movements in Xenopus animal cap explants.

2002 • 37 citations

ARF-Directed Guanine-Nucleotide-Exchange (GEP) Proteins

2003 • 5 citations