Atomic structure of an alpha beta T cell receptor (TCR) heterodimer in complex with an anti-TCR Fab fragment derived from a mitogenic antibody

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

Sequences of proteins of immunological interest

1984 • 3,427 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Analytical molecular surface calculation

1983 • 2,454 citations

Satisfying Hydrogen Bonding Potential in Proteins

1994 • 2,076 citations

An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

1996 • 1,282 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

Three-Dimensional Structure of an Antigen-Antibody Complex at 2.8 Å Resolution

1986 • 1,173 citations

Anatomy of the antibody molecule

1994 • 868 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.

1983 • 861 citations

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

1983 • 833 citations

The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

1988 • 786 citations

The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways

1991 • 782 citations

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

1989 • 778 citations

Crystal structure of globular domain of histone H5 and its implications for nucleosome binding

1993 • 739 citations

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

1984 • 719 citations

OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties

1980 • 718 citations

The outline structure of the T-cell alpha beta receptor.

1988 • 625 citations

Transfer of specificity by murine α and β T-cell receptor genes

1986 • 568 citations

T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases

1993 • 552 citations

Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains

1990 • 549 citations

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

1984 • 528 citations

Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.

1982 • 526 citations

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

1995 • 519 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

1983 • 464 citations

Antigen-like effects of monoclonal antibodies directed at receptors on human T cell clones.

1983 • 435 citations

Structure, function and properties of antibody binding sites

1991 • 426 citations

Analysis and Expression of a Cloned Pre-T Cell Receptor Gene

1994 • 410 citations

Restoration of T Cell Development in RAG-2-Deficient Mice by Functional TCR Transgenes

1993 • 403 citations

Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.

1995 • 393 citations

Structure of myohemerythrin in the azidomet state at resolution

1987 • 377 citations

Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes

1984 • 377 citations

The Major Histocompatibility Complex-Restricted Antigen Receptor on T Cells

1984 • 368 citations

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

1988 • 351 citations

Sequence requirements for induction of cytolysis by the T cell antigenFc receptor ζ chain

1992 • 333 citations

Identification of the components of the murine T cell antigen receptor complex

1985 • 333 citations

T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins.

1991 • 307 citations

Three-dimensional structure of an antigen–antibody complex at 6 Å resolution

1985 • 305 citations

Cross-linking of human T cell receptor proteins: association between the T cell idiotype β subunit and the T3 glycoprotein heavy subunit

1985 • 303 citations

Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition.

1992 • 295 citations

Crystal structure of a T-cell receptor β-chain complexed with a superantigen

1996 • 285 citations

Antibody-antigen interactions

1993 • 282 citations

Genetic and Mutational Analysis of the T-Cell Antigen Receptor

1990 • 275 citations

Crystal Structure of the β Chain of a T Cell Antigen Receptor

1995 • 267 citations

The human T cell receptor: Appearance in ontogeny and biochemical relationship of α and β subunits on IL-2 dependent clones and T cell tumors

1983 • 264 citations

Specific antigen—la activation of transfected human T cells expressing murine Ti αβ —human T3 receptor complexes

1987 • 247 citations

Primary structure of human T-cell receptor α-chain

1984 • 245 citations

A monoclonal antibody blocking human T cell function

1980 • 239 citations

Structure, expression and divergence of T-cell receptor β-chain variable regions

1984 • 237 citations

The Human T-Cell Receptor

1984 • 232 citations

The Antigen-Specific, Major Histocompatibility Complex-Restricted Receptor on T Cells

1986 • 225 citations

Unusual organization and diversity of T-cell receptor a-chain genes

1985 • 212 citations

The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: Identification of constant and variable peptides

1983 • 209 citations

Major antigen-induced domain rearrangements in an antibody

1993 • 206 citations

Improvement of macromolecular electron-density maps by the simultaneous application of real and reciprocal space constraints

1993 • 194 citations

The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides.

1990 • 183 citations

Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor.

1991 • 180 citations

Site-directed mutations in the VDJ junctional region of a T cell receptor β chain cause changes in antigenic peptide recognition

1988 • 180 citations

Crystal Structure of the V _α Domain of a T Cell Antigen Receptor

1995 • 178 citations

Identification of the Receptor for Antigen and Major Histocompatibility Complex on Human Inducer T Lymphocytes

1983 • 165 citations

Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains.

1986 • 143 citations

Comparison of T3-associated 49- and 43-kilodalton cell surface molecules on individual human T-cell clones: evidence for peptide variability in T-cell receptor structures.

1983 • 133 citations

The implications of subunit interactions for the structure of the T cell receptor‐CD3 complex

1990 • 130 citations

Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex.

1991 • 129 citations

Antibody-antigen interactions

1994 • 128 citations

T-cell receptor gene homologs are present in the most primitive jawed vertebrates.

1994 • 117 citations

Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I‐bound determinant

1993 • 116 citations

Structure of the T-cell antigen receptor: evidence for two CD3 epsilon subunits in the T-cell receptor-CD3 complex.

1990 • 110 citations

Intra‐ and extra‐thymic expression of the pre‐T cell receptor α gene

1995 • 109 citations

Evolutionary relationship between the T3 chains of the T-cell receptor complex and the immunoglobulin supergene family.

1987 • 107 citations

Peptide variability exists within alpha and beta subunits of the T cell receptor for antigen.

1983 • 101 citations

Purification and NH2-terminal amino acid sequencing of the beta subunit of a human T-cell antigen receptor.

1984 • 99 citations

The three-dimensional structure of a T-cell antigen receptor Valpha Vbeta heterodimer reveals a novel arrangement of the Vbeta domain

1997 • 99 citations

T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen.

1993 • 97 citations

Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus.

1992 • 86 citations

The T cell antigen receptor α and β chains interact via distinct regions with CD3 chains

1994 • 77 citations

Restricted V-(D)-J junctional regions in the T cell response to lambda-repressor. Identification of residues critical for antigen recognition.

1990 • 76 citations

Function of the pre-T-cell receptor alpha chain in T-cell development and allelic exclusion at the T-cell receptor beta locus.

1996 • 73 citations

Regulation of T cell receptor (TCR)‐β locus allelic exclusion and initiation of TCR‐α locus rearrangement in immature thymocytes by signaling through the CD3 complex

1995 • 73 citations

Regulation of pre-T cell receptor (pT alpha-TCR beta) gene expression during human thymic development.

1996 • 72 citations

Expression of genes encoding the pre-TCR and CD3 complex during thymus development

1995 • 71 citations

Surface expression of alternative forms of the TCR/CD3 complex.

1991 • 68 citations

Structure-function relationships among highly diverse T cells that recognize a determinant from influenza virus hemagglutinin.

1990 • 61 citations

Structural analysis of TCR-ligand interactions studied on H-2Kd-restricted cloned CTL specific for a photoreactive peptide derivative

1995 • 54 citations

T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes.

1987 • 52 citations

Analysis of specificity for antigen, Mls, and allogeneic MHC by transfer of T-cell receptor α- and β-chain genes

1988 • 52 citations

Cloning and comparative analysis of the human pre-T-cell receptor alpha-chain gene.

1995 • 50 citations

Homology of Ti α-subunit of a T-cell antigen–MHC receptor with immunoglobulin

1984 • 46 citations

[26] Screening for heavy-atom derivatives and obtaining accurate isomorphous differences

1997 • 42 citations

Topology of T cell receptor-peptide/class I MHC interaction defined by charge reversal complementation and functional analysis

1997 • 41 citations

Crystallization of a Deglycosylated T Cell Receptor (TCR) Complexed with an Anti-TCR Fab Fragment

1996 • 38 citations

Pre-TCR signaling components trigger transcriptional activation of a rearranged TCR alpha gene locus and silencing of the pre-TCR alpha locus: implications for intrathymic differentiation

1997 • 35 citations

Antibody–antigen flexibility

1987 • 31 citations

Simultaneous involvement of all six predicted antigen binding loops of the T cell receptor in recognition of the MHC/antigenic peptide complex.

1993 • 30 citations

T cell receptor selection by and recognition of two class I major histocompatibility complex-restricted antigenic peptides that differ at a single position.

1993 • 29 citations

Genetic And Mutational Analysis Of The T-Cell Antigen Receptor

1990 • 13 citations

Collaborative computational project no 7 «Analysis of astronomical spectra»

1985 • 11 citations

Major histocompatibility complex recognition by immune receptors: Differences among T cell receptor versus antibody interactions with the VSV8/H‐2K^b complex

1997 • 8 citations