Expression of genes encoding the pre-TCR and CD3 complex during thymus development

Negative selection of lymphocytes

1994 • 810 citations

Positive selection of lymphocytes

1994 • 563 citations

Molecular and Cellular Events of T Cell Development

1989 • 466 citations

Activation of T Cells by a Tyrosine Kinase Activation Domain in the Cytoplasmic Tail of CD3 ε

1992 • 430 citations

Control points in early T-cell development

1993 • 429 citations

Analysis and Expression of a Cloned Pre-T Cell Receptor Gene

1994 • 410 citations

Restoration of T Cell Development in RAG-2-Deficient Mice by Functional TCR Transgenes

1993 • 403 citations

Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer

1985 • 299 citations

Two waves of recombinase gene expression in developing thymocytes.

1994 • 268 citations

A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene.

1994 • 233 citations

The cytoplasmic expression of CD3 antigens in normal and malignant cells of the T lymphoid lineage.

1987 • 181 citations

The Development of Functionally Responsive T Cells

1992 • 169 citations

An activated Ick transgene promotes thymocyte development in rag-1 mutant mice

1994 • 157 citations

Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies

1988 • 147 citations

T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level.

1987 • 118 citations

Development of immature thymocytes: initiation of CD3, CD4, and CD8 acquisition parallels down‐regulation of the interleukin 2 receptor α chain

1990 • 53 citations

Double-negative thymocyte subsets in CD3′ chain-deficient mice: Absence of HSA+CD44−CD25− cells

1994 • 53 citations

Antigen Receptors on T and B Lymphocytes: Parallels in Organization and Function

1993 • 52 citations

The Role of Protein Tyrosine Kinases and Protein Tyrosine Phosphatases in T Cell Antigen Receptor Signal Transduction

1994 • 23 citations

Molecular Components Of T-Cell Recognition

1992 • 23 citations

Genetic And Mutational Analysis Of The T-Cell Antigen Receptor

1990 • 13 citations

Structure, Function, And Serology Of The T-Cell Antigen Receptor Complex

1987 • 9 citations