T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins.

A general method ofin vitropreparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1988 • 2,410 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

1988 • 786 citations

The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways

1991 • 782 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.

1990 • 647 citations

The Receptor with High Affinity for Immunoglobulin E

1986 • 540 citations

Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction.

1990 • 526 citations

T Cell Antigen Receptor-Mediated Activation of Phospholipase C Requires Tyrosine Phosphorylation

1990 • 476 citations

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

1990 • 466 citations

T cell antigen receptor activation pathways: The tyrosine kinase connection

1991 • 442 citations

Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation.

1990 • 432 citations

Co-association of CD3ζ with a receptor (CD16) for IgG Fc on human natural killer cells

1989 • 412 citations

Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides

1991 • 391 citations

Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

1986 • 387 citations

The T Cell Antigen Receptor: Insights into Organelle Biology

1990 • 361 citations

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

1988 • 351 citations

Identification of the components of the murine T cell antigen receptor complex

1985 • 333 citations

T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4.

1984 • 302 citations

Two better cell lines for making hybridomas expressing specific T cell receptors.

1989 • 300 citations

T Cell Activation Induces Rapid Tyrosine Phosphorylation of a Limited Number of Cellular Substrates

1989 • 258 citations

Family of disulphide-linked dimers containing the ζ and η chains of the T-cell receptor and the γ chain of Fc receptors

1990 • 249 citations

A Monoclonal Antibody 7G7/B6, Binds to an Epitope on the Human Interleukin-2 (IL-2) Receptor That is Distinct From That Recognized by IL-2 or Anti-Tac

1985 • 236 citations

Cell growth cycle block of T cell hybridomas upon activation with antigen.

1987 • 235 citations

Characterization and expression of the gene for the human Fc receptor gamma subunit. Definition of a new gene family.

1990 • 225 citations

CD3-negative natural killer cells express ε TCR as part of a novel molecular complex

1989 • 210 citations

A single amino acid in the glycosyl phosphatidylinositol attachment domain determines the membrane topology of FcγRIII

1989 • 189 citations

Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor.

1991 • 180 citations

Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex.

1988 • 180 citations

Fc gamma receptor type III (CD16) is included in the zeta NK receptor complex expressed by human natural killer cells.

1990 • 169 citations

Multiple kinases and signal transduction. Phosphorylation of the T cell antigen receptor complex.

1987 • 168 citations

The T cell antigen receptor zeta chain is tyrosine phosphorylated upon activation.

1988 • 167 citations

Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment.

1988 • 139 citations

Structural Mutations of the T Cell Receptor ζ Chain and Its Role in T Cell Activation

1990 • 132 citations

The implications of subunit interactions for the structure of the T cell receptor‐CD3 complex

1990 • 130 citations

Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex.

1991 • 129 citations

Role of the zeta chain in the expression of the T cell antigen receptor: genetic reconstitution studies.

1989 • 128 citations

src-related tyrosine protein kinases as signaling components in hematopoietic cells.

1990 • 109 citations

Further characterization of the β-component of the receptor for immunoglobulin E

1982 • 106 citations

Activation-Driven Programmed Cell Death and T Cell Receptor ζη Expression

1989 • 98 citations

Molecular cloning of the CD3 eta subunit identifies a CD3 zeta-related product in thymus-derived cells.

1990 • 92 citations

CD3ζ and η chains are produced by alternative splicing from a common gene

1990 • 26 citations