Structure, function and properties of antibody binding sites

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Sequences of proteins of immunological interest

1984 • 3,427 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

Hydrogen bonding in globular proteins

1984 • 1,760 citations

Avidin

1975 • 1,425 citations

AN ANALYSIS OF THE SEQUENCES OF THE VARIABLE REGIONS OF BENCE JONES PROTEINS AND MYELOMA LIGHT CHAINS AND THEIR IMPLICATIONS FOR ANTIBODY COMPLEMENTARITY

1970 • 1,308 citations

Three-Dimensional Structure of an Antigen-Antibody Complex at 2.8 Å Resolution

1986 • 1,173 citations

Hydrophobicity of Amino Acid Residues in Globular Proteins

1985 • 1,168 citations

Conformations of immunoglobulin hypervariable regions

1989 • 1,165 citations

Structural Origins of High-Affinity Biotin Binding to Streptavidin

1989 • 1,162 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

1989 • 989 citations

Hydrophobic bonding and accessible surface area in proteins

1974 • 887 citations

Structural invariants in protein folding

1975 • 865 citations

Affinities of amino acid side chains for solvent water

1981 • 846 citations

Generation of a Large Combinatorial Library of the Immunoglobulin Repertoire in Phage Lambda

1989 • 810 citations

Conformational preferences of amino acids in globular proteins

1978 • 653 citations

Mutation Drift and Repertoire Shift in the Maturation of the Immune Response

1987 • 635 citations

Phosphocholine binding immunoglobulin Fab McPC603

1986 • 576 citations

Regulation of the Assembly and Expression of Variable-Region Genes

1986 • 402 citations

Molecular events during maturation of the immune response to oxazolone

1985 • 380 citations

Structural Basis of Antibody Function

1983 • 371 citations

On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5

1989 • 367 citations

Crystal Structures of an Antibody to a Peptide and Its Complex with Peptide Antigen at 2.8 Å

1990 • 352 citations

Sugar and Signal-Transducer Binding Sites of the Escherichia coli Galactose Chemoreceptor Protein

1988 • 344 citations

Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin new at 2.0 A resolution.

1978 • 293 citations

Three-Dimensional Structure of Antibodies

1988 • 256 citations

On the nature of antibody combining sites: Unusual structural features that may confer on these sites an enhanced capacity for binding ligands

1990 • 233 citations

Three‐dimensional structure of a fluorescein–Fab complex crystallized in 2‐methyl‐2,4‐pentanediol

1989 • 229 citations

On the Specificity of Antibodies

1975 • 217 citations

Chemistry and Biochemistry of the Amino Acids.

1986 • 198 citations

Unusual distributions of amino acids in complementarity-determining (hypervariable) segments of heavy and light chains of immunoglobulins and their possible roles in specificity of antibody-combining sites.

1977 • 196 citations

The galactan‐binding immunoglobulin Fab J539: An x‐ray diffraction study at 2.6‐Å resolution

1986 • 175 citations

Structural plasticity broadens the specificity of an engineered protease

1989 • 165 citations

Antibody Repertoires of Normal BALB/c Mice: B Lymphocyte Populations Defined by State of Activation

1986 • 129 citations

GENE CONVERSION AND THE GENERATION OF ANTIBODY DIVERSITY

1989 • 93 citations

Thermodynamic properties of ligand binding by monoclonal anti-fluorescyl antibodies

1986 • 82 citations

A search for site-filling ligands in the Mcg bence-jones dimer: Crystal binding studies of fluorescent compounds

1984 • 78 citations

The Antibody Combining Site

1977 • 72 citations

GRAMPS - A graphics language interpreter for real-time, interactive, three-dimensional picture editing and animation

1981 • 71 citations

Depth-buffer algorithms for molecular modelling

1985 • 62 citations

Crystal structure of the human Fab fragment Kol and its comparison with the intact Kol molecule

1978 • 59 citations

The binding of opioid peptides to the Mcg light chain dimer: Flexible keys and adjustable locks

1987 • 57 citations

Probing antibody diversity by 2D NMR: comparison of amino acid sequences, predicted structures, and observed antibody-antigen interactions in complexes of two antipeptide antibodies

1989 • 53 citations

Molecular Features and Basic Understanding of Protein-Carbohydrate Interactions: The Arabinose-Binding Protein-Sugar Complex

1988 • 53 citations

Antibodies against a peptide of cholera toxin differing in cross-reactivity with the toxin differ in their specific interactions with the peptide as observed by proton NMR spectroscopy

1990 • 47 citations

GRANNY, a companion to GRAMPS for the real-time manipulation of macromolecular models

1985 • 41 citations

Active site structure and antigen binding properties of idiotypically cross-reactive anti-fluorescein monoclonal antibodies.

1990 • 37 citations

Germ-line affinity and germ-line variable-region genes in the B cell response.

1987 • 31 citations

Of URFS and ORFS: A primer on how to analyse derived amino acid sequences

1988 • 25 citations

Enzyme Structure and Function

2004 • 17 citations

The antibody molecule to common acute lymphocytic leukemia (cALL) antigen used the identical or closely related VH gene segment as that of MOPC-21 immunoglobulin heavy chain.

1985 • 16 citations

Comparative sequence and immunochemical analyses of murine monoclonal anti-morphine antibodies

1989 • 11 citations

Pseudo-dynamic contact surface areas: estimation of apolar bonding

1978 • 11 citations