Characterization of direct radiation-induced immune function and molecular signaling changes in an antigen presenting cell line
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References (51)
THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
1996 • 5,936 citations
The Danger Model: A Renewed Sense of Self
2002 • 4,107 citations
Interleukin-12 and the regulation of innate resistance and adaptive immunity
2003 • 3,689 citations
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.
2001 • 2,603 citations
Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)
1976 • 2,468 citations
Structure, Regulation and Function of NF-kappaB
1994 • 2,110 citations
Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method
2006 • 1,959 citations
Danger signals: SOS to the immune system
2001 • 1,198 citations
NF-κB and the immune response
2006 • 1,124 citations
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
2012 • 737 citations
Human Leukemic Models of Myelomonocytic Development: A Review of the HL-60 and U937 Cell Lines
1985 • 649 citations
IκB kinase complexes: gateways to NF-κB activation and transcription
2006 • 628 citations
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling
2007 • 510 citations
Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
1989 • 473 citations
Transcription Factor NF‐κB: A Sensor for Smoke and Stress Signals
2005 • 420 citations
Combining radiotherapy and immunotherapy: A revived partnership
2005 • 349 citations
A Sense of Danger from Radiation1
2004 • 317 citations
Workshop R: Tumor Immunology, Abstract R1 bis R30
2001 • 312 citations
Prostaglandin E2 and Tumor Necrosis Factor α Cooperate to Activate Human Dendritic Cells: Synergistic Activation of Interleukin 12 Production
1997 • 281 citations
Radiation-induced apoptosis
2000 • 281 citations
N-acetyl-L-cysteine inhibits primary human T cell responses at the dendritic cell level: association with NF-kappaB inhibition.
1999 • 217 citations
Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer.
1999 • 211 citations
In vitro activation of a human macrophage-like cell line
1979 • 205 citations
Immune Modulation by Ionizing Radiation and its Implications for Cancer Immunotherapy
2002 • 200 citations
Dendritic cells resurrect antigens from dead cells
2001 • 192 citations
NF-κB modulation and ionizing radiation: mechanisms and future directions for cancer treatment
2005 • 182 citations
Predominance of NK1.1+TCRαβ+ or DX5+TCRαβ+ T Cells in Mice Conditioned with Fractionated Lymphoid Irradiation Protects Against Graft-Versus-Host Disease: “Natural Suppressor” Cells
2001 • 182 citations
N-Acetyl-<scp>l</scp>-Cysteine Inhibits Primary Human T Cell Responses at the Dendritic Cell Level: Association with NF-κB Inhibition
1999 • 179 citations
Rapid induction of cytokine gene expression in the lung after single and fractionated doses of radiation
1999 • 162 citations
Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration.
2003 • 158 citations
Combination of ?-irradiation and dendritic cell administration induces a potent antitumor response in tumor-bearing mice: Approach to treatment of advanced stage cancer
2001 • 131 citations
Molecular mechanisms of ionizing radiation‐induced apoptosis
1999 • 130 citations
Supplementation of N‐acetylcysteine inhibits NFκB activation and protects against alloxan‐induced diabetes in CD‐1 mice
1999 • 130 citations
Sensors of ionizing radiation effects on the immunological microenvironment of cancer
2007 • 120 citations
Radiation induces upregulation of cyclooxygenase-2 (COX-2) protein in PC-3 cells
2000 • 119 citations
Synergistic antitumor activity of tumor-infiltrating lymphocytes, interleukin 2, and local tumor irradiation. Studies on the mechanism of action.
1990 • 118 citations
Single‐Cell Phospho‐Protein Analysis by Flow Cytometry
2012 • 110 citations
Induction of the Expression of the Interleukin-1β Gene in Mouse Spleen by Ionizing Radiation
1993 • 91 citations
Direct injection of immature dendritic cells into irradiated tumor induces efficient antitumor immunity
2004 • 82 citations
Mechanisms Involved in Radiation Enhancement of Intratumoral Dendritic Cell Therapy
2008 • 80 citations
Use of cell permeable NBD peptides for suppression of inflammation
2006 • 75 citations
The Key Role of IL-6–Arginase Cascade for Inducing Dendritic Cell–Dependent CD4+ T Cell Dysfunction in Tumor-Bearing Mice
2012 • 73 citations
Measurement of Proliferative Responses of Cultured Lymphocytes
2011 • 73 citations
The human macrophage cell line U937 as an in vitro model for selective evaluation of mycobacterial antigen‐specific cytotoxic T‐cell function
2001 • 63 citations
Single‐Cell Phospho‐Protein Analysis by Flow Cytometry
2007 • 52 citations
Effect of Costimulation and the Microenvironment on Antigen Presentation by Leukemic Cells
1999 • 51 citations
Immunotransplantation preferentially expands T-effector cells over T-regulatory cells and cures large lymphoma tumors
2008 • 36 citations
Dynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention
2012 • 32 citations
Dendritic cell activation by danger and antigen‐specific T‐cell signalling
2000 • 26 citations
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling
2007 • 19 citations
Crucial Role of SDF-1/CXCR4 Interaction in the Recruitment of Transplanted Dermal Multipotent Cells to Sublethally Irradiated Bone Marrow
2006 • 14 citations
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