Single‐Cell Phospho‐Protein Analysis by Flow Cytometry

Causal Protein-Signaling Networks Derived from Multiparameter Single-Cell Data

2005 • 1,664 citations

Single Cell Profiling of Potentiated Phospho-Protein Networks in Cancer Cells

2004 • 692 citations

Intracellular phospho-protein staining techniques for flow cytometry: Monitoring single cell signaling events

2003 • 553 citations

Spectral compensation for flow cytometry: Visualization artifacts, limitations, and caveats

2001 • 546 citations

Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling

2006 • 518 citations

Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry

2002 • 282 citations

Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis

1998 • 263 citations

Measurement of MAP kinase activation by flow cytometry using phospho‐specific antibodies to MEK and ERK: Potential for pharmacodynamic monitoring of signal transduction inhibitors

2001 • 179 citations

Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells

2006 • 141 citations

Coordinate Analysis of Murine Immune Cell Surface Markers and Intracellular Phosphoproteins by Flow Cytometry

2005 • 134 citations

Whole blood fixation and permeabilization protocol with red blood cell lysis for flow cytometry of intracellular phosphorylated epitopes in leukocyte subpopulations

2005 • 133 citations

Detection of Intracellular Phosphorylated STAT-1 by Flow Cytometry

1999 • 127 citations

Quantitative single cell determination of ERK phosphorylation and regulation in relapsed and refractory primary acute myeloid leukemia

2005 • 124 citations

Kinetics of B Cell Receptor Signaling in Human B Cell Subsets Mapped by Phosphospecific Flow Cytometry

2006 • 116 citations

K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells

2006 • 114 citations

Sequential paraformaldehyde and methanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins, and intracellular proteins

1992 • 112 citations

Graded Mitogen-Activated Protein Kinase Activity Precedes Switch-Like c-Fos Induction in Mammalian Cells

2005 • 104 citations

Detection of Intracellular Phosphorylated STAT-4 by Flow Cytometry

2001 • 103 citations

Characterization of the Murine Immunological Signaling Network with Phosphospecific Flow Cytometry

2005 • 99 citations

Flow Cytometric Analysis of Kinase Signaling Cascades

2004 • 95 citations

Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53

2006 • 81 citations

T-Cell Tropism and the Role of ORF66 Protein in Pathogenesis of Varicella-Zoster Virus Infection

2005 • 80 citations

Single-cell analysis of signal transduction in CD4 T cells stimulated by antigenin vivo

2001 • 78 citations

The ERK Mitogen-Activated Protein Kinase Pathway Contributes to Ebola Virus Glycoprotein-Induced Cytotoxicity

2006 • 68 citations

Pharmacodynamic monitoring of BAY 43‐9006 (Sorafenib) in phase I clinical trials involving solid tumor and AML/MDS patients, using flow cytometry to monitor activation of the ERK pathway in peripheral blood cells

2006 • 53 citations

Flow cytometric assessment of the signaling status of human B lymphocytes from normal and autoimmune individuals.

2004 • 41 citations

Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level

2006 • 35 citations

Flow cytometric detection of total and serine 473 phosphorylated Akt

2002 • 29 citations

Phospho-specific flow cytometry: intersection of immunology and biochemistry at the single-cell level.

2006 • 26 citations

Flow Cytometric Analysis of T Cell Receptor Signal Transduction

2002 • 13 citations