Inhibition of collagen-induced platelet aggregation as the result of cleavage of α2β1-integrin by the snake venom metalloproteinase jararhagin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

1986 • 1,206 citations

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.

1990 • 851 citations

Hemorrhagic metalloproteinases from snake venoms

1994 • 618 citations

Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia

1985 • 518 citations

Disintegrins: A Family of Integrin Inhibitory Proteins from Viper Venoms

1990 • 497 citations

Identification of a 160,000 dalton platelet membrane protein that mediates the initial divalent cation-dependent adhesion of platelets to collagen

1986 • 409 citations

The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

1989 • 343 citations

Purification, cloning, and molecular characterization of a high molecular weight hemorrhagic metalloprotease, jararhagin, from Bothrops jararaca venom. Insights into the disintegrin gene family

1992 • 325 citations

Trigramin. A low molecular weight peptide inhibiting fibrinogen interaction with platelet receptors expressed on glycoprotein IIb-IIIa complex.

1987 • 323 citations

Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms.

1993 • 290 citations

Poisoning by Bites of the Saw-Scaled or Carpet Viper (<italic>Echis carinatus</italic>) in Nigeria

1977 • 241 citations

Degradation of extracellular matrix proteins by hemorrhagic metalloproteinases

1989 • 224 citations

Inhibition of actin polymerization in blood platelets by cytochalasins

1981 • 200 citations

The α2β1 Integrin: A Collagen Receptor on Platelets and other Cells

1995 • 174 citations

Integrin α2 I-domain is a binding site for collagens

1995 • 172 citations

Analysis of the glycoprotein and protein composition of Bernard-Soulier platelets by single and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

1981 • 151 citations

Identification of putative ligand binding sites within I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29)

1994 • 148 citations

Sequence of a cDNA clone encoding the zinc metalloproteinase hemorrhagic toxin e from Crotalus atrox: evidence for signal, zymogen and disintegrin-like structures

1992 • 147 citations

The complete amino acid sequence of the high molecular mass hemorrhagic protein HR1B isolated from the venom of Trimeresurus flavoviridis.

1990 • 146 citations

A 28-kDa Protein with Disintegrin-like Structure (Jararhagin-C) Purified from Bothrops jararaca Venom Inhibits Collagen- and ADP-Induced Platelet Aggregation

1994 • 142 citations

Inducible Interaction of Integrin α2β1 with Calreticulin

1995 • 137 citations

Jararhagin and Jaracetin: Novel Snake Venom Inhibitors of the Integrin Collagen Receptor, α2β1

1995 • 89 citations

The Hemorrhagin Catrocollastatin Inhibits Collagen-Induced Platelet Aggregation by Binding to Collagen via Its Disintegrin-like Domain

1996 • 84 citations

Interaction of hemorrhagic metalloproteinases with human .alpha.2-macroglobulin

1990 • 80 citations

Properties of Fibrinogen Cleaved by Jararhagin, a Metalloproteinase from the Venom of Bothrops jararaca

1994 • 80 citations

Broad substrate specificity of snake venom fibrinolytic enzymes: Possible role in haemorrhage

1992 • 74 citations

Studies on Blood Coagulation and Fibrinolysis in Patients Bitten by Bothrops jararaca (jararaca)

1990 • 74 citations

Systemic haemorrhage in rats induced by a haemorrhagic fraction from Bothrops jararaca venom

1991 • 73 citations

[2] Isolation of human platelets by albumin gradient and gel filtration

1989 • 61 citations

Ineffectiveness of the inhibition of the main haemorrhagic metalloproteinase from Bothrops jararaca venom by its only plasma inhibitor, α2-macroglobulin

1994 • 51 citations

Leucostoma peptidase A: A metalloprotease from snake venom

1973 • 49 citations

[8] Analysis of collagen receptors

1994 • 44 citations

Isolation and characterization of glycoprotein Ib

1992 • 38 citations

Inventory of Exogenous Inhibitors of Platelet Aggregation

1991 • 35 citations

Fatal extradural haematoma after snake bite (Bothrops moojeni)

1991 • 34 citations

Role of glycoprotein IIa (beta 1 subunit of very late activation antigens) in platelet functions

1991 • 13 citations