A model for sperm-egg binding and fusion based on ADAMs and integrins

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

The Physiology of Reproduction

1988 • 7,765 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

Integrins: Emerging Paradigms of Signal Transduction

1995 • 1,591 citations

A potential fusion peptide and an integrin ligand domain in a protein active in sperm–egg fusion

1992 • 680 citations

VIRUS-CELL AND CELL-CELL FUSION

1996 • 559 citations

A metalloprotease-disintegrin participating in myoblast fusion

1995 • 492 citations

Mouse egg integrin α6β1functions as a sperm receptor

1995 • 472 citations

ADAM, a Widely Distributed and Developmentally Regulated Gene Family Encoding Membrane Proteins with A̱Ḏisintegrin A̱nd M̱etalloprotease Domain

1995 • 406 citations

Calcium oscillations in mammalian eggs triggered by a soluble sperm protein

1996 • 385 citations

Identification of the alpha6 integrin as a candidate receptor for papillomaviruses

1997 • 384 citations

Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion.

1987 • 368 citations

ADAMs in Fertilization and Development

1996 • 259 citations

The Molecules of Mammalian Fertilization

1996 • 239 citations

Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells

1996 • 237 citations

Sequential regulation of alpha 4 beta 1 and alpha 5 beta 1 integrin avidity by CC chemokines in monocytes: implications for transendothelial chemotaxis.

1996 • 220 citations

Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence.

1990 • 219 citations

The exocytotic fusion pore.

1992 • 195 citations

Interaction of the HIV-1 Fusion Peptide with Phospholipid Vesicles: Different Structural Requirements for Fusion and Leakage

1994 • 183 citations

Specific Association Of CD63 with the VLA-3 and VLA-6 Integrins

1995 • 181 citations

Sperm-egg fusion is the prelude to the initial Ca2+ increase at fertilization in the mouse

1997 • 172 citations

Why did the Sperm Cross the Cumulus? To Get to the Oocyte. Functions of the Sperm Surface Proteins PH-20 and Fertilin in Arriving at, and Fusing With, the Egg1

1997 • 171 citations

Mouse sperm-egg plasma membrane interactions: analysis of roles of egg integrins and the mouse sperm homologue of PH-30 (fertilin) β

1995 • 157 citations

Mammalian sperm-egg fusion: The rat egg has complementary sites for a sperm protein that mediates gamete fusion

1992 • 154 citations

Chemokine Receptors and HIV-1: An Attractive Pair?

1996 • 146 citations

ADAMs and cell fusion

1996 • 143 citations

A 28-kDa Protein with Disintegrin-like Structure (Jararhagin-C) Purified from Bothrops jararaca Venom Inhibits Collagen- and ADP-Induced Platelet Aggregation

1994 • 142 citations

Evidence that an Arg-Gly-Asp Adhesion Sequence Plays a Role in Mammalian Fertilization

1990 • 140 citations

To stick or not to stick: the new leukocyte homing paradigm

1996 • 125 citations

Genetic analyses of integrin function in mice

1996 • 124 citations

Effect of the N-terminal glycine on the secondary structure, orientation, and interaction of the influenza hemagglutinin fusion peptide with lipid bilayers

1996 • 119 citations

Molecular Biology of Membrane Transport Disorders

1996 • 110 citations

Identification and localization of integrin subunits in oocytes and eggs of the mouse

1995 • 99 citations

Mammalian oocytes exhibit specific recognition of the RGD (ARG‐Gly‐Asp) tripeptide and express oolemmal integrins

1993 • 97 citations

Activation of Xenopus Eggs by RGD-Containing Peptides Accompanied by Intracellular Ca 2+ Release

1996 • 90 citations

Membrane Interaction and Conformational Properties of the Putative Fusion Peptide of PH-30, a Protein Active in Sperm-Egg Fusion

1994 • 89 citations

Towards molecular mechanisms for gamete adhesion and fusion during mammalian fertilization

1995 • 87 citations

Receptor-induced conformational changes in the subgroup A avian leukosis and sarcoma virus envelope glycoprotein

1995 • 85 citations

Delayed Translation and Posttranslational Processing of Cyritestin, an Integral Transmembrane Protein of the Mouse Acrosome

1995 • 65 citations

The Physiology of Reproduction

1942 • 51 citations

Monoclonal antibodies which recognize equatorial segment epitopes presented de novo following the a23187-induced acrosome reaction of guinea pig sperm

1995 • 46 citations

ADM-1, a protein with metalloprotease- and disintegrin-like domains, is expressed in syncytial organs, sperm, and sheath cells of sensory organs in Caenorhabditis elegans.

1996 • 44 citations

Echovirus 1 interaction with the isolated VLA-2 I domain

1995 • 35 citations

Molecular structure and function of CD4 on murine egg plasma membrane

1995 • 14 citations