Tag-based approaches for transcriptome research and genome annotation

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

2002 • 12,185 citations

Serial Analysis of Gene Expression

1995 • 3,659 citations

Transcriptional Regulatory Networks in Saccharomyces cerevisiae

2002 • 2,967 citations

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

2001 • 2,948 citations

Mechanisms of Alternative Pre-Messenger RNA Splicing

2003 • 2,547 citations

Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome

1998 • 2,163 citations

Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network

2001 • 2,058 citations

A N<scp>EW</scp>A<scp>PPROACH TO</scp>D<scp>ECODING</scp>L<scp>IFE</scp>: Systems Biology

2001 • 1,648 citations

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

2002 • 1,612 citations

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays

2000 • 1,356 citations

Transcriptional Maps of 10 Human Chromosomes at 5-Nucleotide Resolution

2005 • 1,152 citations

Global Identification of Human Transcribed Sequences with Genome Tiling Arrays

2004 • 1,020 citations

Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usage

2003 • 721 citations

Evaluation of gene expression measurements from commercial microarray platforms

2003 • 716 citations

Using the transcriptome to annotate the genome

2002 • 637 citations

Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides

1994 • 584 citations

Global Analysis of the Genetic Network Controlling a Bacterial Cell Cycle

2000 • 562 citations

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

2004 • 554 citations

Novel RNAs Identified From an In-Depth Analysis of the Transcriptome of Human Chromosomes 21 and 22

2004 • 529 citations

Alternative splicing in disease and therapy

2004 • 521 citations

SAGEmap: A Public Gene Expression Resource

2000 • 420 citations

Complex controls: the role of alternative promoters in mammalian genomes

2003 • 316 citations

Getting the Noise Out of Gene Arrays

2004 • 304 citations

High-Efficiency Full-Length cDNA Cloning by Biotinylated CAP Trapper

1996 • 303 citations

Gene expression analysis of plant host–pathogen interactions by SuperSAGE

2003 • 285 citations

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

2000 • 283 citations

Gene identification signature (GIS) analysis for transcriptome characterization and genome annotation

2005 • 243 citations

Cloning of the human cDNA for the U1 RNA-associated 70K protein.

1986 • 235 citations

Digital karyotyping

2002 • 219 citations

[2] High-efficiency full-length cDNA cloning

1999 • 189 citations

Targeting a Complex Transcriptome: The Construction of the Mouse Full-Length cDNA Encyclopedia

2003 • 175 citations

POWER_SAGE: comparing statistical tests for SAGE experiments

2000 • 170 citations

A systems view of mRNP biology

2004 • 161 citations

Discovery of functional noncoding elements by digital analysis of chromatin structure

2004 • 135 citations

5′ Long serial analysis of gene expression (LongSAGE) and 3′ LongSAGE for transcriptome characterization and genome annotation

2004 • 107 citations

Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment

2004 • 104 citations

Characterization of the synthetic compatible solute homoectoine as a potent PCR enhancer

2004 • 97 citations

SuperSAGE

2004 • 81 citations

An Efficient Strategy To Isolate Full-Length cDNAs Based on an mRNA Cap Retention Procedure (CAPture)

1995 • 79 citations

ORFeome Cloning and Systems Biology: Standardized Mass Production of the Parts From the Parts-List

2004 • 76 citations

Assessment of SAGE in Transcript Identification

2003 • 76 citations

Interrogating the transcriptome

2003 • 63 citations

Large heterogeneous nuclear ribonucleic acid has three times as many 5' caps as polyadenylic acid segments, and most caps do not enter polyribosomes.

1981 • 63 citations

Full-length cDNAs: more than just reaching the ends

2001 • 62 citations

DDBJ in collaboration with mass-sequencing teams on annotation

2004 • 41 citations

Comparative evaluation of 5′-end-sequence quality of clones in CAP trapper and other full-length-cDNA libraries

2001 • 41 citations

The impact of SNPs on the interpretation of SAGE and MPSS experimental data

2004 • 40 citations

Genome annotation by high-throughput 5′ RNA end determination

2004 • 28 citations

High-Throughput Gene Discovery in the Rat

2004 • 26 citations

Absolute expression values for mouse transcripts: re‐annotation of the READ expression database by the use of CAGE and EST sequence tags

2004 • 23 citations

SAGE: The Serial Analysis of Gene Expression

2003 • 20 citations

Sage: Current Technologies and Applications

2005 • 16 citations

Removal of PolyA Tails from Full-Length cDNA Libraries for High-Efficiency Sequencing

2001 • 13 citations

5'SAGE: 5'-end Serial Analysis of Gene Expression database

2004 • 10 citations

SAGE: Current Technologies and Applications

2006 • 10 citations