Characterization of the synthetic compatible solute homoectoine as a potent PCR enhancer

Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature

1962 • 4,132 citations

Specific Enzymatic Amplification of DNA In Vitro: The Polymerase Chain Reaction

1986 • 3,400 citations

The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides

1978 • 2,873 citations

The osmophobic effect: natural selection of a thermodynamic force in protein folding 1 1Edited by D. Draper

2001 • 629 citations

Control of Protein Stability and Reactions by Weakly Interacting Cosolvents: The Simplicity of the Complicated

1998 • 613 citations

Betaine Improves the PCR Amplification of GC-Rich DNA Sequences

1997 • 485 citations

Osmoadaptation in Bacteria

1995 • 425 citations

Enzyme stabilization be ectoine-type compatible solutes: protection against heating, freezing and drying

1992 • 409 citations

Cation effects on the denaturation of DNA

1962 • 364 citations

Betaine can eliminate the base pair composition dependence of DNA melting

1993 • 282 citations

Role of water in some biological processes

1990 • 248 citations

Cellular responses to extreme water loss: The water-replacement hypothesis

1982 • 164 citations

Role of water in some biological processes.

1990 • 143 citations

Organic solvents as facilitators of polymerase chain reaction.

1991 • 135 citations

The enhancement of PCR amplification by low molecular-weight sulfones

2001 • 128 citations

Extrinsic protein stabilization by the naturally occurring osmolytes β-hydroxyectoine and betaine

1999 • 123 citations

The enhancement of PCR amplification by low molecular weight amides

2001 • 116 citations

Protection of a model enzyme (lactate dehydrogenase) against heat, urea and freeze-thaw treatment by compatible solute additives

1999 • 89 citations

Expression of the ATP-Binding Cassette Transporter Gene ABCG1 (ABC8) in Tangier Disease

2001 • 73 citations

Genomic Sequence and Structure of the Human ABCG1 (ABC8) Gene

2001 • 70 citations

Effect of Tetrahydropyrimidine Derivatives on Protein-Nucleic Acids Interaction

1999 • 47 citations

Novel Sulfoxides Facilitate GC-Rich Template Amplification

2002 • 45 citations

Conformation of nucleic acids and the analysis of the hypochromic effect

1970 • 28 citations

23Na NMR study of the effect of organic osmolytes on DNA counterion atmosphere

1996 • 25 citations

Low temperature cycled PCR protocol for Klenow fragment of DNA polymerase I in the presence of proline

1999 • 17 citations

Macrophage function and stability of the atherosclerotic plaque: progress report of a European project.

2002 • 10 citations