Is Assembly of the SNARE Complex Enough to Fuel Membrane Fusion?

Intrinsically unstructured proteins and their functions

2005 • 3,690 citations

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1998 • 2,929 citations

SNAREs — engines for membrane fusion

2006 • 2,509 citations

SNAREpins: Minimal Machinery for Membrane Fusion

1998 • 2,456 citations

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

1998 • 2,377 citations

Molecular Anatomy of a Trafficking Organelle

2006 • 2,278 citations

Atomic structure of the ectodomain from HIV-1 gp41

1997 • 1,610 citations

Mechanisms of Viral Membrane Fusion and Its Inhibition

2001 • 1,281 citations

Viral membrane fusion

2008 • 1,129 citations

Mechanics of membrane fusion

2008 • 942 citations

Membranes are more mosaic than fluid

2005 • 873 citations

Molecular architecture of native HIV-1 gp120 trimers

2008 • 805 citations

A trimeric structural domain of the HIV-1 transmembrane glycoprotein

1995 • 699 citations

Natively unfolded proteins

2005 • 698 citations

Mechanisms of membrane fusion: disparate players and common principles

2008 • 675 citations

How Synaptotagmin Promotes Membrane Fusion

2007 • 536 citations

Synaptic vesicle fusion

2008 • 516 citations

Energetics of the HIV gp120-CD4 binding reaction

2000 • 422 citations

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

2007 • 406 citations

Neurotransmitter release — four years of SNARE complexes

1997 • 400 citations

N- to C-Terminal SNARE Complex Assembly Promotes Rapid Membrane Fusion

2006 • 399 citations

Structural Changes Are Associated with Soluble N-Ethylmaleimide-sensitive Fusion Protein Attachment Protein Receptor Complex Formation

1997 • 369 citations

Mixed and Non-cognate SNARE Complexes

1999 • 319 citations

Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide

2008 • 286 citations

Energetics and dynamics of SNAREpin folding across lipid bilayers

2007 • 263 citations

Rapid and efficient fusion of phospholipid vesicles by the α-helical core of a SNARE complex in the absence of an N-terminal regulatory domain

1999 • 259 citations

Hemifusion in SNARE-mediated membrane fusion

2005 • 231 citations

Multiple intermediates in SNARE-induced membrane fusion

2006 • 222 citations

Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins

2002 • 217 citations

A Transient N-terminal Interaction of SNAP-25 and Syntaxin Nucleates SNARE Assembly

2004 • 216 citations

A Structural Change Occurs upon Binding of Syntaxin to SNAP-25

1997 • 214 citations

Virus membrane fusion

2007 • 202 citations

Regulation of Membrane Fusion in Synaptic Excitation-Secretion Coupling: Speed and Accuracy Matter

2007 • 196 citations

Membrane traffic in the secretory pathway

2008 • 196 citations

SNARE assembly and disassembly exhibit a pronounced hysteresis

2002 • 193 citations

Membrane fusion

2002 • 175 citations

Homo- and Heterooligomeric SNARE Complexes Studied by Site-directed Spin Labeling

2001 • 143 citations

SNARE-Mediated Lipid Mixing Depends on the Physical State of the Vesicles

2005 • 141 citations

Neuronal SNAREs Do Not Trigger Fusion between Synthetic Membranes but Do Promote PEG-Mediated Membrane Fusion

2005 • 140 citations

Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion

2006 • 131 citations

Complexin and Ca2+ stimulate SNARE-mediated membrane fusion

2008 • 127 citations

Membrane Fusion Induced by Neuronal SNAREs Transits through Hemifusion

2005 • 126 citations

The neuronal t-SNARE complex is a parallel four-helix bundle.

2001 • 109 citations

HIV-1 gp41: mediator of fusion and target for inhibition.

2004 • 89 citations

Interactions between synaptic vesicle fusion proteins explored by atomic force microscopy

2003 • 88 citations

Distinct Domains of Complexins Bind SNARE Complexes and Clamp Fusion in Vitro

2008 • 60 citations

Membrane Topologies of Neuronal SNARE Folding Intermediates

2002 • 59 citations

Single Molecule Mechanical Probing of the SNARE Protein Interactions

2006 • 49 citations

Regulated exocytosis: merging ideas on fusing membranes

2007 • 46 citations

The Four-helix Bundle of the Neuronal Target Membrane SNARE Complex Is Neither Disordered in the Middle nor Uncoiled at the C-terminal Region

2002 • 43 citations

Interactions of HIV-1 Proteins gp120 and Nef with Cellular Partners Define a Novel Allosteric Paradigm

2004 • 38 citations

Molecular form follows function: (un)snaring the SNAREs

2008 • 34 citations

Interactions between Neuronal Fusion Proteins Explored by Molecular Dynamics

2008 • 29 citations

Comparative Energy Measurements in Single Molecule Interactions

2008 • 23 citations

Experimentelle Übertragungsversuche von Darmausscheidungen leberdystrophie- und hepatitis-epidemica-kranker Menschen auf Wellensittiche(Melopsittacus undulatus)

1947 • 2 citations