Mechanics of membrane fusion

SNAREs — engines for membrane fusion

2006 • 2,509 citations

Membrane Fusion

1990 • 2,458 citations

Coarse Grained Model for Semiquantitative Lipid Simulations

2003 • 2,179 citations

Membrane curvature and mechanisms of dynamic cell membrane remodelling

2005 • 2,031 citations

Membrane Fusion

2003 • 1,265 citations

Viral membrane fusion

2008 • 1,129 citations

Curvature of clathrin-coated pits driven by epsin

2002 • 1,008 citations

The Machines that Divide and Fuse Mitochondria

2007 • 743 citations

Protein-Lipid Interplay in Fusion and Fission of Biological Membranes

2003 • 741 citations

Mechanisms of membrane fusion: disparate players and common principles

2008 • 675 citations

Mesoscopic Undulations and Thickness Fluctuations in Lipid Bilayers from Molecular Dynamics Simulations

2000 • 615 citations

Virus membrane-fusion proteins: more than one way to make a hairpin

2005 • 542 citations

How Synaptotagmin Promotes Membrane Fusion

2007 • 536 citations

Synaptic vesicle fusion

2008 • 516 citations

Lipid-anchored influenza hemagglutinin promotes hemifusion, not complete fusion

1994 • 485 citations

Plasma Membrane Disruption: Repair, Prevention, Adaptation

2003 • 468 citations

Stalk Model of Membrane Fusion: Solution of Energy Crisis

2002 • 425 citations

Crystal Structure of the Low-pH Form of the Vesicular Stomatitis Virus Glycoprotein G

2006 • 416 citations

Membrane fusion

2008 • 401 citations

Tension-induced fusion of bilayer membranes and vesicles

2005 • 390 citations

Energetics of intermediates in membrane fusion: comparison of stalk and inverted micellar intermediate mechanisms

1993 • 388 citations

Separation and Characterization of Late Endosomal Membrane Domains

2002 • 386 citations

The Many Mechanisms of Viral Membrane Fusion Proteins

2004 • 384 citations

The Hydrophobic Insertion Mechanism of Membrane Curvature Generation by Proteins

2008 • 382 citations

The Pathway of Membrane Fusion Catalyzed by Influenza Hemagglutinin: Restriction of Lipids, Hemifusion, and Lipidic Fusion Pore Formation

1998 • 359 citations

The Mechanism of Vesicle Fusion as Revealed by Molecular Dynamics Simulations

2003 • 333 citations

A quantitative model for membrane fusion based on low-energy intermediates

2001 • 318 citations

The Energetics of Membrane Fusion from Binding, through Hemifusion, Pore Formation, and Pore Enlargement

2004 • 308 citations

Observation of a Membrane Fusion Intermediate Structure

2002 • 298 citations

Biomembrane fusion: a new concept derived from model studies using two interacting planar lipid bilayers

1987 • 295 citations

Close Is Not Enough

2000 • 294 citations

Lipid Intermediates in Membrane Fusion: Formation, Structure, and Decay of Hemifusion Diaphragm

2002 • 279 citations

Cell–cell fusion

2007 • 262 citations

Direct Interaction of a Ca2+-binding Loop of Synaptotagmin with Lipid Bilayers

1998 • 259 citations

Structure and function of fusion pores in exocytosis and ectoplasmic membrane fusion

1995 • 249 citations

Elastic energy of tilt and bending of fluid membranes

2000 • 233 citations

Hemifusion in SNARE-mediated membrane fusion

2005 • 231 citations

Direct observation of Bin/amphiphysin/Rvs (BAR) domain-induced membrane curvature by means of molecular dynamics simulations

2006 • 228 citations

The shape of lipid molecules and monolayer membrane fusion

1985 • 226 citations

Fusion of phospholipid vesicles with planar phospholipid bilayer membranes. II. Incorporation of a vesicular membrane marker into the planar membrane.

1980 • 225 citations

The Gaussian Curvature Elastic Modulus of N-Monomethylated Dioleoylphosphatidylethanolamine: Relevance to Membrane Fusion and Lipid Phase Behavior

2004 • 223 citations

Hemifusion arrest by complexin is relieved by Ca2+–synaptotagmin I

2006 • 222 citations

Multiple intermediates in SNARE-induced membrane fusion

2006 • 222 citations

Membrane Fusion

2002 • 215 citations

Self-assembly of amphiphiles into vesicles: A Brownian dynamics simulation

2001 • 212 citations

Non-bilayer lipids and biological fusion intermediates

1996 • 211 citations

An Early Stage of Membrane Fusion Mediated by the Low pH Conformation of Influenza Hemagglutinin Depends upon Membrane Lipids

1997 • 210 citations

Molecular Mechanisms of Membrane Fusion

1988 • 209 citations

Flickering fusion pores comparable with initial exocytotic pores occur in protein-free phospholipid bilayers

1997 • 204 citations

Membranes of the world unite!

2006 • 204 citations

Virus membrane fusion

2007 • 202 citations

Cell-to-cell fusion as a link between viruses and cancer

2007 • 198 citations

Pathway of Membrane Fusion with Two Tension-Dependent Energy Barriers

2007 • 195 citations

Membrane Fusion: Stalk Model Revisited

2002 • 193 citations

Lysolipids reversibly inhibit Ca²⁺‐, GTP‐ and pH‐dependent fusion of biological membranes

1993 • 189 citations

Equivalent Effects of Snake PLA2 Neurotoxins and Lysophospholipid-Fatty Acid Mixtures

2005 • 188 citations

Fusion pathways of vesicles: A Brownian dynamics simulation

2001 • 179 citations

FUSION PORES AND FUSION MACHINES IN CA²⁺-TRIGGERED EXOCYTOSIS

2006 • 178 citations

A new class of fusion-associated small transmembrane (FAST) proteins encoded by the non-enveloped fusogenic reoviruses

2000 • 170 citations

[Possible mechanism of membrane fusion].

1983 • 168 citations

Stoichiometry of Envelope Glycoprotein Trimers in the Entry of Human Immunodeficiency Virus Type 1

2005 • 165 citations

A Mechanism of Protein-Mediated Fusion: Coupling between Refolding of the Influenza Hemagglutinin and Lipid Rearrangements

1998 • 162 citations

Stalk mechanism of vesicle fusion

1989 • 159 citations

Field Theoretic Study of Bilayer Membrane Fusion. I. Hemifusion Mechanism

2004 • 158 citations

Specific Lipids Supply Critical Negative Spontaneous Curvature—An Essential Component of Native Ca2+-Triggered Membrane Fusion

2008 • 157 citations

Membrane deformation by protein coats

2006 • 149 citations

Restricted movement of lipid and aqueous dyes through pores formed by influenza hemagglutinin during cell fusion.

1994 • 149 citations

Molecular Dynamics Simulations of Lipid Vesicle Fusion in Atomic Detail

2007 • 149 citations

A New Mechanism of Model Membrane Fusion Determined from Monte Carlo Simulation

2003 • 147 citations

Protein machines and lipid assemblies: current views of cell membrane fusion

2000 • 144 citations

Tilt model of inverted amphiphilic mesophases

1998 • 141 citations

The transmembrane domain in viral fusion: Essential role for a conserved glycine residue in vesicular stomatitis virus G protein

1998 • 139 citations

Trans-SNARE pairing can precede a hemifusion intermediate in intracellular membrane fusion

2005 • 138 citations

The C. elegans Developmental Fusogen EFF-1 Mediates Homotypic Fusion in Heterologous Cells and In Vivo

2006 • 133 citations

SNAREs can promote complete fusion and hemifusion as alternative outcomes

2005 • 133 citations

Control of Membrane Fusion Mechanism by Lipid Composition: Predictions from Ensemble Molecular Dynamics

2007 • 132 citations

Fusion Peptide of Influenza Hemagglutinin Requires a Fixed Angle Boomerang Structure for Activity

2005 • 124 citations

The fusion pores of Ca2+-triggered exocytosis

2008 • 122 citations

Geranylgeranylated Snares Are Dominant Inhibitors of Membrane Fusion

2000 • 120 citations

Amino Acid Sequence Requirements of the Transmembrane and Cytoplasmic Domains of Influenza Virus Hemagglutinin for Viable Membrane Fusion

1999 • 117 citations

Viral and Developmental Cell Fusion Mechanisms: Conservation and Divergence

2008 • 114 citations

Rabies Virus-Induced Membrane Fusion Pathway

2000 • 109 citations

Field Theoretic Study of Bilayer Membrane Fusion: II. Mechanism of a Stalk-Hole Complex

2005 • 103 citations

Lysophosphatidylcholine reversibly arrests exocytosis and viral fusion at a stage between triggering and membrane merger.

1993 • 97 citations

The Lipid-anchored Ectodomain of Influenza Virus Hemagglutinin (GPI-HA) Is Capable of Inducing Nonenlarging Fusion Pores

2000 • 96 citations

A Rhombohedral Phase of Lipid Containing a Membrane Fusion Intermediate Structure

2003 • 95 citations

Imaging individual retroviral fusion events: From hemifusion to pore formation and growth

2005 • 95 citations

Membrane Remodeling from N-BAR Domain Interactions: Insights from Multi-Scale Simulation

2007 • 94 citations

Stalk Phase Formation: Effects of Dehydration and Saddle Splay Modulus

2004 • 89 citations

Conical Electron Tomography of a Chemical Synapse: Vesicles Docked to the Active Zone are Hemi-Fused

2006 • 86 citations

Osmotic and Curvature Stress Affect PEG-Induced Fusion of Lipid Vesicles but Not Mixing of Their Lipids

2002 • 85 citations

The role of transmembrane domains in membrane fusion

2007 • 84 citations

Assays of vacuole fusion resolve the stages of docking, lipid mixing, and content mixing

2007 • 83 citations

Regulation of Exocytosis in Chromaffin Cells by Trans‐Insertion of Lysophosphatidylcholine and Arachidonic Acid into the Outer Leaflet of the Cell Membrane

2006 • 81 citations

Tilt modulus of a lipid monolayer

2004 • 80 citations

Membrane Permeability Changes at Early Stages of Influenza Hemagglutinin-Mediated Fusion

2003 • 78 citations

Molecular Dynamics Simulation of Spontaneous Membrane Fusion during a Cubic-Hexagonal Phase Transition

2002 • 77 citations

Class II fusion protein of alphaviruses drives membrane fusion through the same pathway as class I proteins

2005 • 72 citations

Reversible Merger of Membranes at the Early Stage of Influenza Hemagglutinin-mediated Fusion

2000 • 70 citations

Effects of Spontaneous Bilayer Curvature on Influenza Virus–mediated Fusion Pores

1998 • 69 citations

Mechanical Coupling via the Membrane Fusion SNARE Protein Syntaxin 1A: A Molecular Dynamics Study

2003 • 69 citations

Membrane Hemifusion Is a Stable Intermediate of Exocytosis

2007 • 68 citations

The Protein Coat in Membrane Fusion: Lessons from Fission

2002 • 66 citations

Time-resolved Imaging of HIV-1 Env-mediated Lipid and Content Mixing between a Single Virion and Cell Membrane

2005 • 66 citations

Multiple Local Contact Sites are Induced by GPI‐Linked Influenza Hemagglutinin During Hemifusion and Flickering Pore Formation

2000 • 58 citations

The lower limit to the size of small sonicated phospholipid vesicles

1982 • 56 citations

Productive Hemifusion Intermediates in Fast Vesicle Fusion Driven by Neuronal SNAREs

2007 • 52 citations

Structure and Energy of Fusion Stalks: The Role of Membrane Edges

2002 • 45 citations

Influenza Hemagglutinins Outside of the Contact Zone Are Necessary for Fusion Pore Expansion

2004 • 44 citations

Calculation of Free Energy Barriers to the Fusion of Small Vesicles

2007 • 42 citations

PLCγ is enriched on poly-phosphoinositide-rich vesicles to control nuclear envelope assembly

2006 • 39 citations

Sec18p and Vam7p remodel trans-SNARE complexes to permit a lipid-anchored R-SNARE to support yeast vacuole fusion

2007 • 36 citations

Influenza virus hemagglutinin-induced cell-planar bilayer fusion: quantitative dissection of fusion pore kinetics into stages.

1993 • 35 citations

A Study of Low pH-Induced Refolding of Env of Avian Sarcoma and Leukosis Virus into a Six-Helix Bundle

2004 • 34 citations

Kinetically Differentiating Influenza Hemagglutinin Fusion and Hemifusion Machines

2003 • 31 citations

Surface Tension, Hydration Energy and Membrane Fusion

1988 • 27 citations

In search of the fusion pore of exocytosis

2006 • 23 citations

Field Theoretic Study of Bilayer Membrane Fusion III: Membranes with Leaves of Different Composition

2007 • 22 citations

Initiation and Dynamics of Hemifusion in Lipid Bilayers

2003 • 21 citations

Dependence of the energies of fusion on the intermembrane separation: Optimal and constrained

2007 • 16 citations

Transmembrane proteins are not required for early stages of nuclear envelope assembly

2006 • 9 citations