Neurotransmitter release — four years of SNARE complexes

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

Mechanisms of intracellular protein transport

1994 • 2,280 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1993 • 1,893 citations

Definition of the Readily Releasable Pool of Vesicles at Hippocampal Synapses

1996 • 1,088 citations

Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects

1995 • 921 citations

Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.

1994 • 798 citations

Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin

1993 • 716 citations

The molecular machinery for secretion is conserved from yeast to neurons.

1993 • 658 citations

Vesicle fusion from yeast to man

1994 • 635 citations

Specificity and regulation of a synaptic vesicle docking complex

1994 • 601 citations

Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins

1995 • 597 citations

Sec18p (NSF)-Driven Release of Sec17p (α-SNAP) Can Precede Docking and Fusion of Yeast Vacuoles

1996 • 580 citations

A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

1994 • 501 citations

Complexins: Cytosolic proteins that regulate SNAP receptor function

1995 • 494 citations

Structure and function of tetanus and botulinum neurotoxins

1995 • 470 citations

Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.

1995 • 455 citations

Protein-Protein Interactions Contributing to the Specificity of Intracellular Vesicular Trafficking

1994 • 401 citations

Syntaxin and synaptobrevin function downstream of vesicle docking in drosophila

1995 • 389 citations

Ca2+ Regulates the Interaction between Synaptotagmin and Syntaxin 1

1995 • 372 citations

Calcium-dependent interaction of N-type calcium channels with the synaptic core complex

1996 • 350 citations

Synaptic vesicle biogenesis, docking, and fusion: a molecular description

1996 • 349 citations

The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling.

1995 • 338 citations

Clostridial neurotoxins: new tools for dissecting exocytosis

1994 • 323 citations

Genetic and electrophysiological studies of drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission

1995 • 321 citations

Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses

1997 • 309 citations

A conserved domain is present in different families of vesicular fusion proteins: A new superfamily

1997 • 308 citations

Direct Interaction of the Rat unc-13 Homologue Munc13-1 with the N Terminus of Syntaxin

1997 • 306 citations

SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

1994 • 288 citations

Calcium-regulated exocytosis is required for cell membrane resealing.

1995 • 278 citations

Assembly and disassembly of a ternary complex of synaptobrevin, syntaxin, and SNAP-25 in the membrane of synaptic vesicles

1997 • 275 citations

Dissection of a single round of vesicular transport: Sequential intermediates for intercisternal movement in the Golgi stack

1989 • 269 citations

rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin.

1995 • 269 citations

The Mammalian Brain rsec6/8 Complex

1996 • 263 citations

Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.

1995 • 262 citations

A post-docking role for synaptobrevin in synaptic vesicle fusion

1994 • 255 citations

Docking of Yeast Vacuoles Is Catalyzed by the Ras-like GTPase Ypt7p after Symmetric Priming by Sec18p (NSF)

1997 • 239 citations

Membrane trafficking in the presynaptic nerve terminal

1995 • 217 citations

A Structural Change Occurs upon Binding of Syntaxin to SNAP-25

1997 • 214 citations

The N-Ethylmaleimide-sensitive Fusion Protein and α-SNAP Induce a Conformational Change in Syntaxin

1995 • 210 citations

Assembly of the ER to Golgi SNARE complex requires Uso1p.

1996 • 203 citations

Distinct domains of syntaxin are required for synaptic vesicle fusion complex formation and dissociation

1995 • 202 citations

Distinct cellular locations of the syntaxin family of proteins in rat pancreatic acinar cells.

1996 • 189 citations

Piccolo, a novel 420 kDa protein associated with the presynaptic cytomatrix.

1996 • 181 citations

Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytoplasmic domains.

1994 • 162 citations

Clostridial neurotoxins compromise the stability of a low energy SNARE complex mediating NSF activation of synaptic vesicle fusion.

1995 • 150 citations

SNAP-25 Is Required for a Late Postdocking Step in Ca2+-dependent Exocytosis

1996 • 148 citations

Exocytosis: Proteins and Perturbations

1996 • 123 citations

Transcytosis-associated protein (TAP)/p115 is a general fusion factor required for binding of vesicles to acceptor membranes.

1995 • 114 citations

Is NSF a fusion protein?

1995 • 96 citations

Biochemical requirements for the targeting and fusion of ER-derived transport vesicles with purified yeast Golgi membranes.

1996 • 92 citations

v- and t-SNAREs in neuronal exocytosis: A need for additional components to define sites of release

1995 • 66 citations

Adrenal chromaffin cells contain functionally different SNAP‐25 monomers and SNAP‐25/syntaxin heterodimers

1996 • 66 citations

Effect of Mutations in Vesicle-Associated Membrane Protein (VAMP) on the Assembly of Multimeric Protein Complexes

1997 • 58 citations

A Possible Predocking Attachment Site for N-Ethylmaleimide-sensitive Fusion Protein

1996 • 55 citations

Inhibition of transmitter release correlates with the proteolytic activity of tetanus toxin and botulinus toxin A in individual cultured synapses of Hirudo medicinalis.

1997 • 52 citations

Inhibition of Transmitter Release Correlates with the Proteolytic Activity of Tetanus Toxin and Botulinus Toxin A in Individual Cultured Synapses ofHirudo medicinalis

1997 • 39 citations