SNAREpins: Minimal Machinery for Membrane Fusion

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

A rapid, sensitive, and specific method for the determination of protein in dilute solution

1973 • 2,518 citations

Mechanisms of intracellular protein transport

1994 • 2,280 citations

Core Structure of gp41 from the HIV Envelope Glycoprotein

1997 • 1,904 citations

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1993 • 1,893 citations

Atomic structure of the ectodomain from HIV-1 gp41

1997 • 1,610 citations

Intracellular protein topogenesis

1980 • 1,378 citations

Use of resonance energy transfer to monitor membrane fusion

1981 • 1,274 citations

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

1992 • 1,274 citations

Protein Sorting by Transport Vesicles

1996 • 1,168 citations

Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface

1992 • 968 citations

The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.

1996 • 839 citations

The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations.

1989 • 819 citations

Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.

1994 • 798 citations

Structure and Conformational Changes in NSF and Its Membrane Receptor Complexes Visualized by Quick-Freeze/Deep-Etch Electron Microscopy

1997 • 788 citations

Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin

1993 • 716 citations

A trimeric structural domain of the HIV-1 transmembrane glycoprotein

1995 • 699 citations

The syntaxin family of vesicular transport receptors

1993 • 656 citations

Specificity and regulation of a synaptic vesicle docking complex

1994 • 601 citations

Sec18p (NSF)-Driven Release of Sec17p (α-SNAP) Can Precede Docking and Fusion of Yeast Vacuoles

1996 • 580 citations

SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast

1990 • 578 citations

VAMP-1: a synaptic vesicle-associated integral membrane protein.

1988 • 574 citations

Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport.

1988 • 519 citations

Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain.

1989 • 513 citations

A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

1994 • 501 citations

Lipid-anchored influenza hemagglutinin promotes hemifusion, not complete fusion

1994 • 485 citations

Fluorescence assay for phospholipid membrane asymmetry

1991 • 484 citations

Homotypic vacuolar fusion mediated by t- and v-SNAREs

1997 • 457 citations

Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.

1995 • 455 citations

The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral cell surface domains of MDCK cells.

1986 • 446 citations

p47 is a cofactor for p97-mediated membrane fusion

1997 • 436 citations

The Vesicle Docking Protein p115 Binds GM130, a cis-Golgi Matrix Protein, in a Mitotically Regulated Manner

1997 • 408 citations

Real-time measurement of transmitter release from single synaptic vesicles

1995 • 404 citations

Protein-Protein Interactions Contributing to the Specificity of Intracellular Vesicular Trafficking

1994 • 401 citations

Synaptic Vesicles and Exocytosis

1994 • 371 citations

Structural Changes Are Associated with Soluble N-Ethylmaleimide-sensitive Fusion Protein Attachment Protein Receptor Complex Formation

1997 • 369 citations

An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic golgi fragments

1995 • 354 citations

Structural Organization of the Synaptic Exocytosis Core Complex

1997 • 352 citations

Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

1991 • 347 citations

The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling.

1995 • 338 citations

Docked granules, the exocytic burst, and the need for ATP hydrolysis in endocrine cells

1995 • 337 citations

Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae

1993 • 316 citations

Rab GTPases: master regulators of membrane trafficking

1994 • 315 citations

Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses

1997 • 309 citations

SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

1994 • 288 citations

Syntaxin 6 functions in trans-Golgi network vesicle trafficking.

1997 • 286 citations

Dissection of a single round of vesicular transport: Sequential intermediates for intercisternal movement in the Golgi stack

1989 • 269 citations

Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.

1995 • 262 citations

A Vacuolar v–t-SNARE Complex, the Predominant Form In Vivo and on Isolated Vacuoles, Is Disassembled and Activated for Docking and Fusion

1998 • 255 citations

Syntaxin 5 Is a Common Component of the NSF- and p97-Mediated Reassembly Pathways of Golgi Cisternae from Mitotic Golgi Fragments In Vitro

1998 • 254 citations

Structure and function of fusion pores in exocytosis and ectoplasmic membrane fusion

1995 • 249 citations

A rat brain Sec1 homologue related to Rop and UNC18 interacts with syntaxin.

1994 • 247 citations

A Structural Change Occurs upon Binding of Syntaxin to SNAP-25

1997 • 214 citations

TRANSPORT VESICLE DOCKING: SNAREs and Associates

1996 • 207 citations

N-Ethylmaleimide-sensitive Factor Acts at a Prefusion ATP-dependent Step in Ca2+-activated Exocytosis

1996 • 206 citations

Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4

1993 • 190 citations

Subunit structure of the mammalian exocyst complex

1997 • 186 citations

The HA2 subunit of influenza hemagglutinin inserts into the target membrane prior to fusion.

1991 • 186 citations

SNAP-25 Is Required for a Late Postdocking Step in Ca2+-dependent Exocytosis

1996 • 148 citations

Organelle Membrane Fusion: A Novel Function for the Syntaxin Homolog Ufe1p in ER Membrane Fusion

1998 • 146 citations

A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum

1997 • 141 citations

Lipid interactions of the hemagglutinin HA2 NH2-terminal segment during influenza virus-induced membrane fusion.

1992 • 139 citations

THE USE OF EXOGENOUS FLUORESCENT PROBES FOR TEMPERATURE MEASUREMENTS IN SINGLE LIVING CELLS

1995 • 137 citations

Vesicles on strings: Morphological evidence for processive transport within the Golgi stack

1998 • 128 citations

SNAREs and the specificity of transport vesicle targeting

1995 • 123 citations

The fusion pore and mechanisms of biological membrane fusion

1996 • 120 citations

How Do Viruses Enter Cells? The HIV Coreceptors Teach Us a Lesson of Complexity

1997 • 110 citations

Throttles and Dampers: Controlling the Engine of Membrane Fusion

1997 • 107 citations

Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4

1993 • 105 citations

SNARE Proteins‐Why So Many, Why So Few?

1997 • 88 citations

Dithionite penetration through phospholipid bilayers as a measure of defects in lipid molecular packing

1993 • 83 citations

Truncation of the COOH-terminal region of the paramyxovirus SV5 fusion protein leads to hemifusion but not complete fusion.

1996 • 73 citations

HIV-1 gp41 Tertiary Structure Studied by EPR Spectroscopy

1996 • 35 citations

Botulinum neurotoxin light chains inhibit both Ca²⁺‐induced and GTP analogue‐induced catecholamine release from permeabilised adrenal chromaffin cells

1996 • 34 citations

Transbilayer Lipid Redistribution Accompanies Poly(ethylene glycol) Treatment of Model Membranes but Is Not Induced by Fusion

1997 • 31 citations

SNAREs Involved in Traffic through the Golgi Complex

1995 • 22 citations

In Vivo Labeling of Over-Expressed Recombinant Proteins in E. coli

1997 • 7 citations