Molecular architecture of native HIV-1 gp120 trimers

Computer Visualization of Three-Dimensional Image Data Using IMOD

1996 • 5,410 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1998 • 2,929 citations

HIV Entry and Its Inhibition

1998 • 1,270 citations

The antigenic structure of the HIV gp120 envelope glycoprotein

1998 • 1,206 citations

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

2002 • 894 citations

Visualizing density maps with UCSF Chimera

2006 • 889 citations

HIV vaccine design and the neutralizing antibody problem

2004 • 778 citations

Structural definition of a conserved neutralization epitope on HIV-1 gp120

2007 • 768 citations

Distribution and three-dimensional structure of AIDS virus envelope spikes

2006 • 735 citations

Structure of a V3-Containing HIV-1 gp120 Core

2005 • 732 citations

Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding.

1991 • 598 citations

Structure of an unliganded simian immunodeficiency virus gp120 core

2005 • 513 citations

Energetics of the HIV gp120-CD4 binding reaction

2000 • 422 citations

Inactivation of Human Immunodeficiency Virus Type 1 Infectivity with Preservation of Conformational and Functional Integrity of Virion Surface Proteins

1998 • 422 citations

Oligomeric Modeling and Electrostatic Analysis of the gp120 Envelope Glycoprotein of Human Immunodeficiency Virus

2000 • 263 citations

Cryo-Electron Tomographic Structure of an Immunodeficiency Virus Envelope Complex In Situ

2006 • 231 citations

Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein

1997 • 221 citations

Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding.

1990 • 214 citations

Electron Tomography of the Contact between T Cells and SIV/HIV-1: Implications for Viral Entry

2007 • 181 citations

Classification and 3D averaging with missing wedge correction in biological electron tomography

2008 • 172 citations

3D reconstruction and processing of volumetric data in cryo-electron tomography

2006 • 160 citations

Identification of a New Quaternary Neutralizing Epitope on Human Immunodeficiency Virus Type 1 Virus Particles

2005 • 149 citations

The V1, V2, and V3 Regions of the Human Immunodeficiency Virus Type 1 Envelope Differentially Affect the Viral Phenotype in an Isolate-Dependent Manner

2005 • 118 citations

Antibody-Based HIV-1 Vaccines: Recent Developments and Future Directions

2007 • 87 citations

A Replication-Competent, Neutralization-Sensitive Variant of Simian Immunodeficiency Virus Lacking 100 Amino Acids of Envelope

2002 • 82 citations

Bridging the imaging gap: visualizing subcellular architecture with electron tomography

2005 • 70 citations

HIV-1 Neutralization: Mechanisms and Relevance to Vaccine Design

2007 • 54 citations

Cryoelectron Tomographic Analysis of an HIV-neutralizing Protein and Its Complex with Native Viral gp120

2007 • 40 citations

Conformational Rearrangement within the Soluble Domains of the CD4 Receptor Is Ligand-specific

2007 • 31 citations