Mechanism of All-TransRetinoic Acid Effect on Tumor-Associated Myeloid-Derived Suppressor Cells

Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers

1999 • 1,593 citations

Increased Production of Immature Myeloid Cells in Cancer Patients: A Mechanism of Immunosuppression in Cancer

2001 • 1,309 citations

Antigen-Specific Inhibition of CD8+ T Cell Response by Immature Myeloid Cells in Cancer Is Mediated by Reactive Oxygen Species

2004 • 825 citations

Arginase-Producing Myeloid Suppressor Cells in Renal Cell Carcinoma Patients: A Mechanism of Tumor Evasion

2005 • 811 citations

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

2006 • 798 citations

The promise of retinoids to fight against cancer

2001 • 763 citations

Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression

2005 • 752 citations

Nuclear retinoid receptors and the transcription of retinoid-target genes

2004 • 739 citations

Mechanism of Immune Dysfunction in Cancer Mediated by Immature Gr-1+ Myeloid Cells

2001 • 536 citations

All-trans-Retinoic Acid Improves Differentiation of Myeloid Cells and Immune Response in Cancer Patients

2006 • 529 citations

Reduction of Myeloid-Derived Suppressor Cells and Induction of M1 Macrophages Facilitate the Rejection of Established Metastatic Disease

2005 • 462 citations

Hyperactivation of STAT3 Is Involved in Abnormal Differentiation of Dendritic Cells in Cancer

2004 • 458 citations

All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination.

2003 • 457 citations

Map kinase signaling pathways and hematologic malignancies

2003 • 433 citations

Role Of Immature Myeloid Cells in Mechanisms of Immune Evasion In Cancer

2005 • 352 citations

Regulation of Dendritic Cell Differentiation and Antitumor Immune Response in Cancer by Pharmacologic-Selective Inhibition of the Janus-Activated Kinase 2/Signal Transducers and Activators of Transcription 3 Pathway

2005 • 308 citations

Tumor-Associated CD8+ T Cell Tolerance Induced by Bone Marrow-Derived Immature Myeloid Cells

2005 • 302 citations

Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species

2003 • 289 citations

Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest.

1998 • 254 citations

Up-Regulation of the Human γ-Glutamylcysteine Synthetase Regulatory Subunit Gene Involves Binding of Nrf-2 to an Electrophile Responsive Element

1999 • 238 citations

T cell surface redox levels determine T cell reactivity and arthritis susceptibility

2006 • 235 citations

Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage

2002 • 179 citations

Rapid Effects of Retinoic Acid on CREB and ERK Phosphorylation in Neuronal Cells

2004 • 176 citations

Evidence for the role of an altered redox state in hyporesponsiveness of synovial T cells in rheumatoid arthritis.

1997 • 170 citations

Reactive Oxygen Species and 12/15-Lipoxygenase Contribute to the Antiproliferative Capacity of Alternatively Activated Myeloid Cells Elicited during Helminth Infection

2005 • 144 citations

Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage

2002 • 128 citations

Combined Deficiency of p50 and cRel in CD4+ T Cells Reveals an Essential Requirement for Nuclear Factor κB in Regulating Mature T Cell Survival and In Vivo Function

2003 • 127 citations

Cloning and characterization of the human glutathione synthetase 5′-flanking region

2005 • 77 citations

Tumour necrosis factor α induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor κB and activator protein-1

2005 • 76 citations

All‐trans retinoic acid skews monocyte differentiationinto interleukin‐12‐secreting dendritic‐like cells

2003 • 65 citations

Retinoic acid selectively activates the ERK2 but not JNK/SAPK or P38 map kinases when inducing myeloid differentiation

1999 • 55 citations

Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency

2005 • 49 citations

Role of the nrf-2 gene in protection and repair of gastric mucosa against oxidative stress

2005 • 44 citations

Retinoic acid modulation of glutathione and cysteine metabolism in chondrocytes

1996 • 39 citations

Intracellular glutathione levels determine cell sensitivity to apoptosis induced by the antineoplasic agent N-(4-hydroxyphenyl) retinamide.

2005 • 38 citations

Cellular redox state and its relationship to the inhibition of clonal cell growth and the induction of apoptosis during all-trans retinoic acid exposure in acute myeloblastic leukemia cells.

2000 • 27 citations

Tretinoin prevents age-related renal changes and stimulates antioxidant defenses in cultured renal mesangial cells.

1999 • 21 citations