Arginase-Producing Myeloid Suppressor Cells in Renal Cell Carcinoma Patients: A Mechanism of Tumor Evasion

Arginase I Production in the Tumor Microenvironment by Mature Myeloid Cells Inhibits T-Cell Receptor Expression and Antigen-Specific T-Cell Responses

2004 • 1,136 citations

Mechanisms and functional significance of tumour-induced dendritic-cell defects

2004 • 995 citations

Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients.

2001 • 860 citations

Randomized Phase III Trial of High-Dose Interleukin-2 Versus Subcutaneous Interleukin-2 and Interferon in Patients With Metastatic Renal Cell Carcinoma

2004 • 801 citations

L-arginine metabolism in myeloid cells controls T-lymphocyte functions

2003 • 580 citations

IL-4-Induced Arginase 1 Suppresses Alloreactive T Cells in Tumor-Bearing Mice

2003 • 499 citations

<scp>l</scp>-Arginine Consumption by Macrophages Modulates the Expression of CD3ζ Chain in T Lymphocytes

2003 • 458 citations

Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

2002 • 408 citations

Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity

2004 • 319 citations

Immunoregulatory T cells in tumor immunity

2004 • 257 citations

Lymphocyte apoptosis induced by Fas ligand- expressing ovarian carcinoma cells. Implications for altered expression of T cell receptor in tumor-associated lymphocytes.

1998 • 238 citations

Arginase activity in human breast cancer cell lines: N(omega)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells.

2000 • 181 citations

Immortalized Myeloid Suppressor Cells Trigger Apoptosis in Antigen-Activated T Lymphocytes

2000 • 155 citations

Analysis of amino acids in human serum by isocratic reversed-phase high-performance liquid chromatography with electrochemical detection

2001 • 149 citations

L-Arginine regulates the expression of the T-cell receptor zeta chain (CD3zeta) in Jurkat cells.

2001 • 113 citations

Stimulation of human breast cancers by dietary <scp>l</scp>-arginine

1992 • 69 citations

ALTERATIONS IN ARGININE METABOLIC ENZYMES IN TRAUMA

2001 • 65 citations

Surgical Stress Induces Decreased Expression of Signal-Transducing Zeta Molecules in T Cells

1999 • 28 citations