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The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

2003 • 1,266 citations

Forkhead Transcription Factor FKHR-L1 Modulates Cytokine-Dependent Transcriptional Regulation of p27^KIP1

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The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2.

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Forkhead Transcription Factors Are Critical Effectors of Cell Death and Cell Cycle Arrest Downstream of PTEN

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Chemistry and Significance of Condensed Tannins

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The Flavonoids

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Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene.

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A DNA Damage–Induced p53 Serine 392 Kinase Complex Contains CK2, hSpt16, and SSRP1

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Cdc2 Phosphorylation of BAD Links the Cell Cycle to the Cell Death Machinery

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Glutamine and Cancer

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Cancer Chemoprevention and Apoptosis Mechanisms Induced by Dietary Polyphenolics

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A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth

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Basis for the selective cytotoxicity of rhodamine 123.

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Glucose turnover, gluconeogenesis from glycerol, and estimation of net glucose cycling in cancer patients

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Retinoic acid–induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27Kip1

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Phosphorylation on Tyrosine-15 of p34Cdc2 by ErbB2 Inhibits p34Cdc2 Activation and Is Involved in Resistance to Taxol-Induced Apoptosis

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Oncogenes in tumor metabolism, tumorigenesis, and apoptosis.

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Studies in Polyphenol Chemistry and Bioactivity. 4.¹ Synthesis of Trimeric, Tetrameric, Pentameric, and Higher Oligomeric Epicatechin-Derived Procyanidins Having All-4β,8-Interflavan Connectivity and Their Inhibition of Cancer Cell Growth through Cell Cycle Arrest¹

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Distinct pattern of p53 phosphorylation in human tumors

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Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells

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Inhibition of aberrant proliferation and induction of apoptosis in pre-neoplastic human mammary epithelial cells by natural phytochemicals.

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Suppression of the p53- or pRB-mediated G1 checkpoint is required for E2F-induced S-phase entry

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Mitochondria and disease

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F16, a Mitochondriotoxic Compound, Triggers Apoptosis or Necrosis Depending on the Genetic Background of the Target Carcinoma Cell

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Overexpression of c-Myc Alters G₁/S Arrest following Ionizing Radiation

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Additive effects of c‐erbB‐2, c‐Ha‐ras, and transforming growth factor‐α genes on in vitro transformation of human mammary epithelial cells

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Layered expression scanning: rapid molecular profiling of tumor samples.

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Structural Variations in Proanthocyanidins and Their Derivatives

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The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities.

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Antioxidants and cancer prevention

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Correlation of TP53 Mutations and p53 Expression in Ovarian Tumors

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Effects of monensin liposomes on the cytotoxicity, apoptosis and expression of multidrug resistance genes in doxorubicin-resistant human breast tumour (MCF-7/dox) cell-line

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Phosphoinositide 3-kinase and Forkhead, a switch for cell division

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Ion transport in epithelial spheroids derived from human airway cells

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pRb and Cdk regulation by N-(4-hydroxyphenyl)retinamide

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Frequent phosphorylation at serine 392 in overexpressed p53 protein due to missense mutation in carcinoma of the urinary tract

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Review: significance of, and optimal screening for, HER-2 gene amplification and protein overexpression in breast carcinoma.

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Transforming Growth Factor β Inhibits the Phosphorylation of pRB at Multiple Serine/Threonine Sites and Differentially Regulates the Formation of pRB Family–E2F Complexes in Human Myeloid Leukemia Cells

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Multimembrane dot-blotting: a cost-effective tool for proteome analysis

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Distinct pattern of p53 phosphorylation in human cancers

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Profiling the expression of mitogen-induced T-cell proteins by using multi-membrane dot-blotting

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