Antidepressant-induced hepatotoxicity

Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study

1997 • 7,096 citations

Drug-Induced Hepatotoxicity

2003 • 1,591 citations

Criteria of drug-induced liver disorders

1990 • 1,071 citations

Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability

2000 • 937 citations

Pharmacokinetic-Pharmacodynamic Consequences and Clinical Relevance of Cytochrome P450 3A4 Inhibition

2000 • 877 citations

Potential Role of Pharmacogenomics in Reducing Adverse Drug Reactions

2001 • 689 citations

Screening for Depression: Recommendations and Rationale

2002 • 522 citations

Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: Analysis of instances of therapeutic misadventure

1995 • 436 citations

Ischemic hepatitis: clinical presentation and pathogenesis

2000 • 347 citations

Selective Serotonin Reuptake Inhibitors and Cytochrome P-450 Mediated Drug-Drug Interactions: An Update

2002 • 344 citations

Selective serotonin reuptake inhibitors: a review of efficacy and tolerability in depression

2000 • 318 citations

Drug-Induced Hepatotoxicity

1995 • 291 citations

Clinical pharmacology of imipramine and related antidepressant compounds.

1967 • 274 citations

Comparison of two clinical scales for causality assessment in hepatotoxicity

2001 • 262 citations

Biochemical and Cellular Mechanisms of Toxic Liver Injury

2002 • 241 citations

The Safety of Fluoxetine - An Update

1988 • 230 citations

Isoniazid and Iproniazid: Activation of Metabolites to Toxic Intermediates in Man and Rat

1976 • 228 citations

Drug-induced liver disease

2000 • 223 citations

Pharmacology of antidepressants

2001 • 188 citations

A review of the common properties of drugs with idiosyncratic hepatotoxicity and the “multiple determinant hypothesis” for the manifestation of idiosyncratic drug toxicity

2002 • 178 citations

A Comparison of Paroxetine, Imipramine and Placebo in Depressed Out-patients

1991 • 175 citations

Metabolism of the Newer Antidepressants

1998 • 174 citations

Adolescent Depression

2002 • 144 citations

Depressive illness

1999 • 135 citations

Incidence of parenchymal liver diseases in Denmark, 1981 to 1985: analysis of hospitalization registry data. The Danish Association for the Study of the Liver.

1991 • 132 citations

Fluoxetine treatment of depression caused by interferon-alpha.

1993 • 129 citations

Plasma membrane cytochromes P450 as neoantigens and autoimmune targets in drug-induced hepatitis

1997 • 129 citations

Mechanisms of Hepatic Transport of Drugs: Implications for Cholestatic Drug Reactions

2002 • 114 citations

Hepatotoxicity of psychotropic drugs

1999 • 113 citations

Hepatotoxicity Associated With the New Antidepressants

2002 • 104 citations

Nefazodone-Induced Liver Failure: Report of Three Cases

1999 • 101 citations

Antecedent liver disease and drug toxicity

1999 • 92 citations

Role of reactive metabolites in drug-induced hepatitis

1995 • 89 citations

An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.

1988 • 81 citations

Moclobemide

1996 • 81 citations

Possible role of HLA in hepatotoxicity

1994 • 80 citations

Risks and Benefits of Selective Serotonin Reuptake Inhibitors in the Treatment of Depression

1998 • 79 citations

The rational use of potentially hepatotoxic medications in patients with underlying liver disease

2002 • 72 citations

Drug hepatotoxicity

2002 • 70 citations

Fluoxetine disposition and elimination in cirrhosis

1988 • 67 citations

Changes in the pattern of antidepressant use upon the introduction of the new antidepressants: a prescription database study

1997 • 65 citations

Tolerance after liver transplantation: does it exist and can immunosuppression be withdrawn?

1999 • 64 citations

Hepatocellular Jaundice as a Complication of Iproniazid Therapy

1960 • 63 citations

Tianeptine, a new tricyclic antidepressant metabolized by β-oxidation of its heptanoic side chain, inhibits the mitochondrial oxidation of medium and short chain fatty acids in mice

1989 • 62 citations

Effect of bolus injection and continuous infusion of somatostatin on gastric perfusion in cirrhotic patients with portal-hypertensive gastropathy

1994 • 59 citations

Acute liver injury associated with the use of ebrotidine, a new H 2 -receptor antagonist

1999 • 55 citations

A new antimitochondria antibody (anti-M6) in iproniazid-induced hepatitis.

1982 • 54 citations

Inhibition of Trazodone Metabolism by Thioridazine in Humans

1995 • 54 citations

Prolonged cholestasis and progressive hepatic fibrosis following imipramine therapy

1980 • 53 citations

Trazodone-Induced Hepatotoxicity: A Case Report With Comments on Drug-Induced Hepatotoxicity

2000 • 53 citations

Toxicity of tricyclic antidepressants to isolated rat hepatocytes

1975 • 53 citations

Drug points: Paroxetine and hepatotoxicity

1997 • 52 citations

Acute Hepatitis Due to Fluoxetine Therapy

1999 • 51 citations

Genetic predisposition to drug hepatotoxicity: Role in hepatitis caused by amineptine, a tricyclic antidepressant

1989 • 48 citations

Preclinical toxicology of bupropion: an overview.

1983 • 43 citations

Lethal Hepatic Necrosis After Therapy With Imipramine and Desipramine

1968 • 43 citations

Acute liver failure after treatment with nefazodone.

1999 • 41 citations

[Evolution of antidepressive drug consumption in Spain. The impact of selective serotonin re-uptake inhibitors].

1997 • 39 citations

Acute Hepatic Necrosis Following Treatment with Amitriptyline and Diazepam

1965 • 38 citations

Chronic hepatitis related to use of fluoxetine.

1997 • 37 citations

Chronic liver injury related to use of bentazepam: an unusual instance of benzodiazepine hepatotoxicity.

2000 • 36 citations

New antidepressants: use in high-risk patients.

1993 • 36 citations

Drug Points

1994 • 35 citations

Hepatitis Caused by Amitriptyline Therapy

1975 • 34 citations

Tianeptine — an instance of drug-induced hepatotoxicity predicted by prospective experimental studies

1994 • 32 citations

Cross hepatotoxicity between tricyclic antidepressants.

1986 • 32 citations

Symptomatic liver injury probably related to sertraline.

1998 • 32 citations

Acute hepatitis induced by bupropion.

2000 • 32 citations

Fluoxetine-induced hepatitis: why is postmarketing surveillance needed?

1999 • 30 citations

Hepatic injury caused by mianserin.

1989 • 29 citations

Reversible nefazodone-induced liver failure.

2000 • 29 citations

Acute cholestatic hepatitis induced by bupropion prescribed as pharmacological support to stop smoking. A case report

2001 • 27 citations

Metabolic activation of the new tricyclic antidepressant tianeptine by human liver cytochrome P450

1990 • 27 citations

Chronic Active Hepatitis Associated with Trazodone Therapy

1993 • 26 citations

Severe hepatotoxicity with jaundice associated with paroxetine

2001 • 25 citations

Severe liver injury due to phenelzine with unique hepatic deposition of extracellular material

1986 • 24 citations

Cross hepatotoxicity between tricyclic antidepressants and phenothiazines.

1995 • 23 citations

Amitriptyline-Induced Fulminant Hepatitis

1984 • 23 citations

Jaundice Associated with Amitriptyline

1969 • 23 citations

Reversible Hepatotoxicity of Paroxetine in a Patient with Major Depression

1996 • 23 citations

Hepatotoxicity in patients with cirrhosis, an often unrecognized problem: lessons from a fatal case related to amoxicillin/clavulanic acid.

2001 • 21 citations

HEPATOTOXICITY OF ANESTHETICS AND OTHER CENTRAL NERVOUS SYSTEM DRUGS

1995 • 21 citations

Liver Injury Associated With Tranylcypromine Therapy

1964 • 21 citations

Hepatic Failure Associated with Imipramine Therapy

1990 • 20 citations

Acute Liver Failure with Concurrent Bupropion and Carbimazole Therapy

2003 • 19 citations

Acute cholestasis by fluoxetine.

1996 • 17 citations

Hepatotoxicity of Citalopram in Rats and First-Pass Metabolism

1978 • 17 citations

Amineptine induced liver injury. Report of two cases and brief review of the literature.

1996 • 16 citations

Jaundice and eosinophilia associated with amitriptyline.

1978 • 16 citations

Nortriptyline-Induced Hepatic Failure

1996 • 15 citations

A Study of Blood Count and Serum Transaminase in Prolonged Treatment with Amitriptyline

1962 • 14 citations

Clotiazepam-induced acute hepatitis

1989 • 13 citations

Desipramine-associated hepatitis.

1983 • 13 citations

Concurrent Agranulocytosis and Hepatitis Secondary to Clomipramine Therapy

1993 • 13 citations

[Acute hepatitis during treatment with fluoxetine].

1991 • 12 citations

Hepatitis aguda por ticlopidina. Presentación de 12 casos y revisión de la literatura

2001 • 11 citations

MORPHOLOGICAL AND BIOCHEMICAL ALTERATION IN THE RAT LIVER INDUCED BY MAPROTILINE

1975 • 11 citations

Case Report of Hepatotoxicity Associated with Maprotiline

1988 • 10 citations

[Acute hepatitis during treatment with fluoxetine].

1993 • 10 citations

Hepatitis Caused by Antidepressive Therapy with Maprotiline and Opipramol

1998 • 9 citations

Hepatic Failure Associated with Imipramine Therapy

1996 • 9 citations

[Severe hepatitis attributed to paroxetine (Seroxat)].

1997 • 9 citations

A prospective evaluation of the hepatotoxicity of lofepramine in the elderly

1993 • 9 citations

[Behavioral disorders after treatment with isoniazid].

2001 • 8 citations

[Hepatitis probably secondary to the massive ingestion of fluvoxamine].

1988 • 8 citations

Hepatotoxicity associated with maprotiline therapy: case report.

1984 • 7 citations

Hépatotoxicité de la miansérine: un cas avec réintroduction positive.

1992 • 7 citations

Acute Liver Failure with Concurrent Bupropion and Carbimazole Therapy

2003 • 7 citations

[Acute mixed hepatitis caused by tianeptine].

1996 • 6 citations

[Hepatitis due to amineptin. 4 cases].

1982 • 6 citations

[Hepatitis and amineptin].

1981 • 5 citations

Hepatic injury associated with amineptine therapy.

1990 • 4 citations

[Acute cytolytic hepatitis caused by amoxapine].

1993 • 4 citations

[Fever and liver function disorders caused by nomifensine (Alival)].

1980 • 4 citations

[Acute liver necrosis after treatment with opipramol].

1977 • 4 citations

Amoxapine Associated with Hepatotoxicity

1987 • 3 citations

[Acute benign hepatitis probably due to maprotiline].

1988 • 3 citations

[Auxiliary hepatic transplantation in iproniazid-induced subfulminant hepatitis. Should iproniazid still be sold in France?].

1999 • 3 citations

[Chronic cirrhogenic hepatitis caused by amineptin (Survector)?].

1985 • 1 citations

[Immediate acute hepatic cytolysis after the administration of a single amineptin tablet].

1992 • 1 citations

Deleted Work

1955 • 0 citations