Human T-cell receptor variable gene segment families

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Sequences of proteins of immunological interest

1984 • 3,427 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1988 • 940 citations

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

1984 • 719 citations

Human T-cell receptor variable gene segment families

1995 • 663 citations

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

1984 • 652 citations

Polymerase Chain Reaction with Single-Sided Specificity: Analysis of T Cell Receptor δ Chain

1989 • 640 citations

The outline structure of the T-cell alpha beta receptor.

1988 • 625 citations

Transfer of specificity by murine α and β T-cell receptor genes

1986 • 568 citations

Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy

1988 • 555 citations

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

1984 • 528 citations

Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells

1988 • 522 citations

Antibody framework residues affecting the conformation of the hypervariable loops

1992 • 507 citations

CDR3 length in antigen-specific immune receptors.

1994 • 503 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

1987 • 483 citations

The Structure, Function, and Molecular Genetics of the gamma/delta T Cell Receptor

1989 • 476 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

Somatic recombination in a murine T-cell receptor gene

1984 • 468 citations

Structure, Organization and Polymorphism of Murine and Human T‐Cell Receptor a and β Chain Gene Families

1988 • 448 citations

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

1986 • 423 citations

A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product

1987 • 408 citations

Diversity, rearrangement, and expression of murine T cell gamma genes

1986 • 405 citations

Structure, organization, and somatic rearrangement of T cell gamma genes

1985 • 395 citations

Sequence and expression of transcripts of the human T-cell receptor β- chain genes

1984 • 380 citations

Correlations between T-cell specificity and the structure of the antigen receptor

1986 • 375 citations

In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes

1988 • 374 citations

Diversity and rearrangement of the human T cell rearranging γ genes: Nine germ-line variable genes belonging to two subgroups

1986 • 329 citations

T-cell receptor δ gene rearrangements in early thymocytes

1987 • 324 citations

Genes of the T-Cell Antigen Receptor in Normal and Malignant T Cells

1987 • 321 citations

The adult T-cell receptor 5-chain is diverse and distinct from that of fetal thymocytes

1988 • 320 citations

The EMBL data library.

1988 • 314 citations

The human t cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene

1984 • 306 citations

Murine T-cell receptor mutants with deletions of beta-chain variable region genes.

1986 • 304 citations

Gene for α-Chain of Human T-Cell Receptor: Location on Chromosome 14 Region Involved in T-Cell Neoplasms

1985 • 300 citations

Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin new at 2.0 A resolution.

1978 • 293 citations

Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus.

1994 • 289 citations

The murine T-cell receptor uses a limited repertoire of expressed Vβ gene segments

1985 • 283 citations

Diversity and structure of human T-cell receptor alpha-chain variable region genes.

1987 • 274 citations

Primary structure of human T-cell receptor α-chain

1984 • 245 citations

Structure, expression and divergence of T-cell receptor β-chain variable regions

1984 • 237 citations

Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire.

1994 • 232 citations

Diversity and structure of genes of the α family of mouse T-cell antigen receptor

1985 • 228 citations

Structure and specificity of T cell receptor gamma/delta on major histocompatibility complex antigen-specific CD3+, CD4-, CD8- T lymphocytes.

1988 • 227 citations

Sequences and repertoire of the human T cell receptor α and β chain variable region genes in thymocytes

1987 • 226 citations

Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line.

1985 • 225 citations

Complexity of human T-cell antigen receptor β-chain constant- and variable-region genes

1984 • 213 citations

Unusual organization and diversity of T-cell receptor a-chain genes

1985 • 212 citations

Predominant use of a Vα gene segment in mouse T-cell receptors for cytochrome c

1986 • 206 citations

The T cell receptor β chain genes are located on chromosome 6 in mice and chromosome 7 in humans

1984 • 204 citations

Selection of Amino Acid Sequences in the Beta Chain of the T Cell Antigen Receptor

1988 • 203 citations

Genomic organization of the genes encoding mouse T-cell receptor α-chain

1985 • 202 citations

Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor α-chain

1985 • 201 citations

A T cell clone expresses two T cell receptor α genes but uses one αβ heterodimer for allorecognition and self MHC-restricted antigen recognition

1988 • 200 citations

T-Cell Receptor β-Chain Expression: Dependence on Relatively Few Variable Region Genes

1985 • 197 citations

Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α‐mRNA of BW5147 origin

1989 • 188 citations

Identification of Putative Human T Cell Receptor δ Complementary DNA Clones

1987 • 187 citations

Limited diversity of the rearranged T-cell γ gene

1985 • 185 citations

Rearrangement of two distinct T-cell γ-chain variable-region genes in human DNA

1986 • 174 citations

New subgroups in the human T cell rearranging V gamma gene locus.

1987 • 170 citations

The Human T-Cell Receptor TCRAC/TCRDC (Cα/Cdelta;) Region: Organization, Sequence, and Evolution of 97.6 kb of DNA

1994 • 169 citations

Fusion of an immunoglobulin variable gene and a T cell receptor constant gene in the chromosome 14 inversion associated with T cell tumors

1985 • 166 citations

The extent of the human germline T-cell receptor V beta gene segment repertoire

1994 • 164 citations

Excision products of the T cell receptor gene support a progressive rearrangement model of the alpha/delta locus.

1989 • 162 citations

Identification and sequence of a fourth human T cell antigen receptor chain

1987 • 157 citations

T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes.

1986 • 154 citations

Direct evidence for chromosomal inversion during T-cell receptor β-gene rearrangements

1986 • 151 citations

Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility complex recognition.

1992 • 150 citations

Studies on the human T cell receptor α/β variable region genes. II. Identification of four additional V_β subfamilies

1991 • 148 citations

Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor.

1992 • 140 citations

Sequences and diversity of human T cell receptor beta chain variable region genes.

1986 • 140 citations

Limited receptor repertoire in a mycobacteria-reactive subset of γδ T lymphocytes

1989 • 138 citations

Diversity and structure of human T cell receptor delta chain genes in peripheral blood gamma/delta-bearing T lymphocytes.

1989 • 137 citations

Analysis of DNA surrounding the breakpoints of chromosomal translocations involving the β T cell receptor gene in human lymphoblastic neoplasms

1987 • 136 citations

Human T-cell-receptor delta chain: genomic organization, diversity, and expression in populations of cells.

1988 • 136 citations

A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci

1986 • 136 citations

Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor CαCδ region

1992 • 134 citations

Athymic mice express a high level of functional γ-chain but greatly reduced levels of α- and β-chain T-cell receptor messages

1986 • 133 citations

Sequences and repertoire of human T cell receptor alpha chain variable region genes in mature T lymphocytes.

1986 • 132 citations

Variability and repertoire size of T-cell receptor Vα gene segments

1985 • 131 citations

Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors.

1985 • 122 citations

The EMBL Network File Server

1989 • 122 citations

Vβ17 gene polymorphism in wild-derived mouse strains: Two amino acid substitutions in the Vβ17 region greatly alter T cell receptor specificity

1990 • 122 citations

Studies on the human T cell receptor α/β variable region genes. I. Identification of 7 additional V_α subfamilies and 14 J_α gene segments

1991 • 121 citations

Rearranged β t cell receptor genes in a helper t cell clone specific for lysozyme: No correlation between Vβ and MHC restriction

1985 • 120 citations

Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes.

1988 • 117 citations

Genomic organization of the human T-cell antigen-receptor alpha/delta locus.

1988 • 113 citations

T cell receptor-gamma and -delta genes preferentially utilized by adult thymocytes for the surface expression.

1989 • 110 citations

The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia.

1985 • 107 citations

Diversity and organization of human T cell receptor delta variable gene segments.

1989 • 107 citations

Complex rearrangements within the human J delta-C delta/J alpha-C alpha locus and aberrant recombination between J alpha segments.

1988 • 105 citations

Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes.

1987 • 105 citations

The human T cell receptor beta-chain gene complex contains at least 57 variable gene segments. Identification of six V beta genes in four new gene families.

1991 • 105 citations

Characterization of an expressed CDS-associated Ti γ-chain reveals Cγ domain polymorphism

1987 • 101 citations

Sequence and evolution of the human T-cell antigen receptor beta-chain genes.

1985 • 99 citations

Dominance of one T-cell receptor in the H–2Kb/TNP response

1987 • 98 citations

In vivo clonal dominance and limited T-cell receptor usage in human CD4+ T-cell recognition of house dust mite allergens.

1993 • 98 citations

A soluble, single-chain T-cell receptor fragment endowed with antigen-combining properties.

1991 • 97 citations

Molecular analysis of a t(14;14) translocation in leukemic T-cells of an ataxia telangiectasia patient.

1989 • 96 citations

Clonal diversity and T-cell receptor beta-chain variable gene expression in enlarged lymph nodes of MRL-lpr/lpr lupus mice.

1986 • 96 citations

Variability in T cell receptor V beta gene usage in human peripheral blood lymphocytes. Studies of identical twins, siblings, and insulin-dependent diabetes mellitus patients.

1992 • 95 citations

Repertoire of the human T cell gamma genes: high frequency of nonfunctional transcripts in thymus and mature T cells

1987 • 92 citations

Human T-cell γ genes contain N segments and have marked junctional variability

1986 • 87 citations

Molecular analysis of the antigen receptor of virus‐specific cytotoxic T cells and identification of a new V_α family

1987 • 87 citations

The joining of germ-line Vα to Jα genes replaces the preexisting Vα-Jα complexes in a T cell receptor α,β positive T cell line

1988 • 87 citations

Allelic variations in the human T cell receptor V beta 6.7 gene products.

1990 • 85 citations

Structurally Divergent Human T Cell Receptor γ Proteins Encoded by Distinct Cγ Genes

1987 • 84 citations

Characterization of the human T cell receptor α‐chain repertoire and demonstration of a genetic influence on Vα usage

1993 • 84 citations

Characterization of a third form of the human T cell receptor gamma/delta.

1988 • 83 citations

Physical Maps of the Mouse and Human Immunoglobulin-like Loci

1989 • 83 citations

Biased T cell receptor V_α region repertoire in the synovial fluid of rheumatoid arthritis patients

1991 • 82 citations

T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments.

1986 • 82 citations

Comparison of human and mouse T-cell receptor variable gene segment subfamilies

1995 • 81 citations

Identical Vβ T-cell receptor genes used in alloreactive cytotoxic and antigen plus I–A specific helper T cells

1985 • 79 citations

Nomenclature for T-cell receptor (TCR) gene segments of the immune system

1995 • 78 citations

T cell receptor alpha chain genes are located on chromosome 14 at 14q11-14q12 in humans.

1985 • 77 citations

The T cell receptor V?3 gene segment is associated with reactivity to p-azobenzenearsonate

1988 • 76 citations

Human T-cell tumours containing chromosome 14 inversion or translocation with breakpoints proximal to immunoglobulin joining regions at 14q32.

1987 • 75 citations

Structure and Diversity of the Human T-Cell Receptor β-Chain Variable Region Genes

1986 • 74 citations

Further analysis of the T cell receptor gamma/delta+ peripheral lymphocyte subset. The V delta 1 gene segment is expressed with either C alpha or C delta.

1990 • 74 citations

Genomically imposed and somatically modified human thymocyte V beta gene repertoires.

1991 • 74 citations

Human T cell clones reactive against U-small nuclear ribonucleoprotein autoantigens from connective tissue disease patients and healthy individuals.

1993 • 74 citations

The breakpoint of an inversion of chromosome 14 in a T-cell leukemia: sequences downstream of the immunoglobulin heavy chain locus are implicated in tumorigenesis.

1987 • 72 citations

Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain.

1986 • 71 citations

The mechanism of chromosome 14 inversion in a human T cell lymphoma

1987 • 70 citations

Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice.

1990 • 69 citations

The human T-cell receptor γ (TRG) genes

1989 • 68 citations

T cell receptor variable gene usage in a specific cytotoxic T cell response. Primary structure of the antigen-MHC receptor of four hapten-specific cytotoxic T cell clones.

1987 • 68 citations

Allelic sequence variations in the hypervariable region of a T-cell receptor beta chain: correlation with restriction fragment length polymorphism in human families and populations.

1989 • 67 citations

Molecular basis for the nonexpression of V beta 17 in some strains of mice.

1988 • 64 citations

Generation of diversity of the beta chain of the human T-lymphocyte receptor for antigen.

1986 • 64 citations

Restricted V-segment usage in T-cell receptors from cytotoxic T lymphocytes specific for a major epitope of lymphocytic choriomeningitis virus

1990 • 63 citations

New human V beta genes and polymorphic variants.

1991 • 63 citations

Analysis of a human V beta gene subfamily.

1986 • 63 citations

The T cell receptor V alpha 11 gene family. Analysis of allelic sequence polymorphism and demonstration of J alpha region-dependent recognition by allele-specific antibodies.

1991 • 62 citations

Predominant use of a particular α-chain in suppressor T cell hybridomas specific for keyhole limpet hemocyanin

1989 • 62 citations

Structure-function relationships among highly diverse T cells that recognize a determinant from influenza virus hemagglutinin.

1990 • 61 citations

Normal T cell development is possible without ‘functional’ gamma chain genes.

1986 • 60 citations

GenBank

1991 • 60 citations

Thymocyte circular DNA excised from T cell receptor alpha-delta gene complex.

1988 • 59 citations

Each of the two productive T cell receptor α-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an α chain which can contribute to the constitution of a surface-expressed αβ dimer

1991 • 59 citations

No functional γ-chain transcripts detected in an alloreactive cytotoxic T-cell clone

1986 • 57 citations

Predominant variable region gene usage by gamma/delta T cell receptor-bearing cells in the adult thymus.

1988 • 57 citations

Partial Primary Structure of the Alpha and Beta Chains of Human Tumor T-Cell Receptors

1985 • 57 citations

A new mouse TCR V gamma gene that shows remarkable evolutionary conservation.

1987 • 57 citations

Identification and physical mapping of a polymorphic human T cell receptor V beta gene with a frequent null allele.

1993 • 57 citations

T cell receptor gene usage in the response to lambda repressor cI protein. An apparent bias in the usage of a V alpha gene element.

1988 • 54 citations

Measuring the Human T Cell Receptor γ-Chain Locus

1987 • 52 citations

Thymic ontogeny and selection of αβ and γδ T cells

1989 • 52 citations

The genomic structure of human V beta 6 T cell antigen receptor genes.

1991 • 51 citations

Promoter and enhancer elements in the rearranged alpha chain gene of the human T cell receptor.

1987 • 50 citations

Receptor diversity of insulin-specific T cell lines from C57BL (H-2b) mice.

1987 • 50 citations

A novel type of aberrant T cell receptor alpha-chain gene rearrangement. Implications for allelic exclusion and the V-J recombination process.

1990 • 50 citations

Functional α and β T cell chain receptor messages can be detected in old but not in young athymic mice

1987 • 49 citations

Restriction fragment length polymorphisms of the mouse T-cell receptor gene families

1989 • 48 citations

T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas.

1989 • 48 citations

Subgroups of variable region genes of beta chains of T-cell receptors for antigen.

1986 • 47 citations

Systematic study of human αβ T cell receptor V segments shows allelic variations resulting in a large number of distinct T cell receptor haplotypes

1993 • 45 citations

Organization of human T-cell receptor beta-chain genes: clusters of V beta genes are present on chromosomes 7 and 9.

1993 • 45 citations

T-cell antigen receptors with identical variable regions but different diversity and joining region gene segments have distinct specificities but cross-reactive idiotypes.

1987 • 44 citations

Transcription of Germ Line Vα Segments Correlates with Ongoing T-Cell Receptor α-Chain Rearrangement

1992 • 44 citations

Use of a variable alpha region to create a functional T-cell receptor delta chain.

1988 • 44 citations

Alternative splicing of murine T-cell receptor β-chain transcripts

1986 • 44 citations

Variable region (V delta) gene segment most frequently utilized in adult thymocytes is 3' of the constant (C delta) region.

1988 • 44 citations

Reduced expression of a human V beta 6.1 T-cell receptor allele.

1993 • 43 citations

Molecular analysis of antigen recognition by insulin-specific T-cell hybridomas from B6 wild-type and bm12 mutant mice.

1987 • 42 citations

Structure of extrachromosomal circular DNAs excised from T-cell antigen receptor alpha and delta-chain loci

1988 • 42 citations

Delta-chains of dendritic epidermal T cell receptors are diverse but pair with gamma-chains in a restricted manner.

1989 • 42 citations

Identification and characterization of new murine T cell receptor beta chain variable region (V beta) genes.

1989 • 41 citations

The structure of Vα and Jα segments in the mouse

1988 • 41 citations

T cell receptor beta-chain genes in BW5147 and other AKR tumors. Deletion order of murine V beta gene segments and possible 5' regulatory regions.

1988 • 40 citations

Detection of human T cell receptor cDNAs (α, β, γ and δ) by ligation of a universal adaptor to variable region

1993 • 39 citations

The V gamma locus of the human T cell receptor gamma gene. Repertoire polymorphism of the first variable gene segment subgroup.

1988 • 39 citations

Abnormal recombination products result from aberrant DNA rearrangement of the human T-cell antigen receptor beta-chain gene.

1986 • 39 citations

Nucleotide Sequence Analysis of 77.7 kb of the Human Vβ T-Cell Receptor Gene Locus: Direct Primer-Walking Using Cosmid Template DNAs

1994 • 38 citations

T cell receptor γ cDNA in human fetal liver and thymus: Variable regions of γ chains are restricted to VγI or V9, due to the absence of splicing of the V10 and V11 leader intron

1994 • 38 citations

Unusual forms of T cell γ mRNA in a human T cell leukemia cell line: Implications for γ gene expression

1987 • 36 citations

Two distinct mechanisms account for the immune response (Ir) gene control of the T cell response to pigeon cytochrome c.

1988 • 36 citations

Transcription of germ line V alpha segments correlates with ongoing T-cell receptor alpha-chain rearrangement.

1992 • 35 citations

Coding sequence polymorphisms among V beta T cell receptor genes.

1990 • 34 citations

Novel members and germline polymorphisms in the human T-cell receptor Vb6 family

1993 • 34 citations

Rearrangement by inversion of a T-cell receptor delta variable region gene located 3' of the delta constant region gene.

1989 • 34 citations

Few V gene segments dominate the T cell receptor beta-chain repertoire of the human thymus.

1993 • 33 citations

A nomenclature to fit the organization of the human T-cell receptor γ and δ genes

1990 • 33 citations

Asymmetric selection of T cell antigen receptor alpha- and beta-chains in HLA-B27 alloreactivity.

1992 • 31 citations

On the mechanism of non-allelically excluded V alpha-J alpha T cell receptor secondary rearrangements in a murine T cell lymphoma.

1990 • 31 citations

Profound alteration in an alpha beta T-cell antigen receptor repertoire due to polymorphism in the first complementarity-determining region of the beta chain.

1991 • 30 citations

Beta-chain gene rearrangements and V beta gene usage in DPw2-specific T cells.

1987 • 29 citations

Post-transcriptional allelic exclusion of two functionally rearranged T cell receptor α genes

1989 • 29 citations

Evidence for expression of two distinct T cell receptor beta-chain transcripts in a human diphtheria toxoid-specific T cell clone.

1988 • 29 citations

Preferential association of α and β chains of the T cell antigen receptor

1992 • 29 citations

Nonrandom T cell receptor usage in the allorecognition of HLA-DR1 microvariation.

1993 • 28 citations

Rearrangement and Expression of T-Cell Antigen Receptor Genes in Human T-Lymphocyte Tumor Lines and Normal Human T-Cell Clones: Evidence for Allelic Exclusion of Tiβ Gene Expression and Preferential Use of a Jβ2 Gene Segment

1986 • 28 citations

Novel excision products of T cell receptor γ gene rearrangements and developmental stage specificity implied by the frequency of nucleotide insertions at signal joints

1992 • 27 citations

Identification of a T cell receptor beta chain variable region, V beta 20, that is differentially expressed in various strains of mice.

1991 • 25 citations

Generation of monoclonal antibodies against soluble human T cell receptor polypeptides

1991 • 25 citations

Secretion of disulfide-linked human T-cell receptor gamma delta heterodimers

1993 • 24 citations

Organization and orientation of a human T cell receptor δ chain V gene segment that suggests an inversion mechanism is utilized in its rearrangement

1989 • 24 citations

Coding Region Polymorphisms of Human T‐Cell Receptor Vβ6.9 and Vβ21.4

1992 • 24 citations

First genomic sequence of the human T-cell receptor δ2 gene (TRDV2)

1989 • 24 citations

Human T-cell receptor Vα gene polymorphism

1991 • 24 citations

T-cell receptor beta-chain gene usage in the T-cell recognition of Mycobacterium leprae antigens in one tuberculoid leprosy patient.

1992 • 23 citations

Oligoclonal T Cells in Rheumatoid Arthritis: Identification Strategy and Molecular Characterization of a Clonal T‐Cell Receptor

1992 • 23 citations

The complete primary structure of the T -Cell receptor genes from an alloreactive cytotoxic human T-lymphocyte clone

1986 • 22 citations

Restriction of the T-cell receptor V delta gene repertoire is due to preferential rearrangement and is independent of antigen selection

1995 • 21 citations

The T cell receptor from an influenza-A specific murine CTL clone

1989 • 21 citations

Silent allelic variants of a T-cell receptor Vβ12 gene are present in diverse human populations

1992 • 21 citations

The antigen receptor of an autoreactive T-cell clone from human rheumatic synovia

1989 • 20 citations

Sequence and expression of a novel human T-cell receptor ?-chain variable gene segment subfamily

1990 • 20 citations

MALIGNED: a multiple sequence alignment editor

1992 • 20 citations

A T-cell receptor ??-specific monoclonal antibody detects a V?5 region polymorphism

1992 • 20 citations

Further evidence for a gamma/delta T cell receptor-mediated TCT.1/CD48 recognition.

1991 • 20 citations

Thymocyte development: an analysis of T cell receptor gene expression in 519 newborn thymocyte hybridomas

1989 • 20 citations

Conserved V(D)J junctional sequence of cross‐reactive cytotoxic T cell receptor idiotype and the effect of a single amino acid substitution

1991 • 19 citations

Change in antigen specificity of cytotoxic T lymphocytes is associated with the rearrangement and expression of a T-cell receptor beta-chain gene.

1986 • 19 citations

Allelic polymorphism of human T-cell receptor V alpha gene segments

1993 • 19 citations

Frequent recombination in the human T-cell receptor beta gene complex

1994 • 18 citations

TCR gene segments from at least one third of Va subfamilies rearrange at the δ locus

1994 • 17 citations

Reciprocal hybrid joints demonstrate successive V - J rearrangements on the same chromosome in the human TCR gamma locus

1991 • 17 citations

Molecular Analysis of Antigen Recognition by Insulin-Specific T-Cell Hybridomas from B6 Wild-Type and bm12 Mutant Mice

1987 • 16 citations

A highly homologous T-cell receptor ?-chain variable region is expressed in mouse and human T cells

1985 • 13 citations

Two autologous melanoma-specific and MHC-restricted human T cell clones with identical intra-tumour reactivity do not share the same TCR Vα and Vβ gene families

1991 • 13 citations

Molecular analysis of T-cell receptor transcripts in a human T-cell leukemia bearing a t(1;14) and an inv(7); cell surface expression of a TCR-beta chain in the absence of alpha chain.

1993 • 12 citations

Polymorphisms in the Tcrb-V2 gene segments localize the Tcrb orphon genes to human chromosome 9p21

1993 • 12 citations

Identification of novel human T-cell receptor V? gene segments by the anchored-polymerase chain reaction

1992 • 11 citations

Allelic differences in TCR gamma-chains alter gamma delta T cell antigen reactivity.

1994 • 11 citations

Human T-cell receptor TCRAV, TCRBV, and TCRAJ sequences newly found in T-cell clones reactive with allogeneic HLA class II antigens

1993 • 10 citations

Structure of the gamma/delta T cell receptor of a human thymocyte clone.

1988 • 10 citations

Polymorphism detection and sequence analysis of human T-cell receptor V?-chain-encoding gene segments

1994 • 10 citations

Expression of T cell receptor genes in an antigen-specific hybridoma and radiation-induced variants.

1986 • 10 citations

Sequences of four previously undescribed human T‐cell receptor β chain variable genes

1991 • 10 citations

Isolation of cDNA clones encoding a T-cell receptor beta-chain from a beef insulin-specific hybridoma.

1985 • 10 citations

Organization, Sequence, and Function of 34.5 kb of Genomic DNA Encompassing Several Murine T-Cell Receptor α/δ Variable Gene Segments

1994 • 10 citations

A new mouse T-cell receptorα chain variable region family

1991 • 9 citations

Characterization of a novel human T cell receptor β chain variable region family by transspecies DNA hybridization

1994 • 9 citations

Subgroups of Tcr ? chains and correlation with T-cell function

1992 • 9 citations

Nucleotide sequence of a cDNA corresponding to a new human variable region of a functionally rearranged T cell receptor gamma chain

1987 • 9 citations

Non-germ-line elements (NGE) are present in the T cell receptor beta-chain genes isolated from the mutant mouse, motheaten (me/me).

1986 • 9 citations

Amino acid sequences of seven V?, eight V?, and thirteen J? novel human TCR genes

1993 • 8 citations

Analysis of human T-cell receptor α-chain cDNAs isolated from peripheral blood mononuclear cells

1992 • 8 citations

T cell receptor alpha and beta gene expression in a murine antigen-specific T suppressor lymphocyte clone with cytolytic potential.

1991 • 8 citations

Unexpected consistent involvement of V beta gene segments in inappropriate T-cell receptor beta gene rearrangements occurring in B- lineage acute lymphoblastic leukemias

1992 • 8 citations

A joining–diversity–joining complex generated by inversion mechanism and a variable–diversity complex in the β–chain gene of the human Tcell receptor

1986 • 7 citations

Polymorphism of the Tcrg-V1-V2 region in mice: identification of a new Vg1 allele in DBA/2

1992 • 7 citations

Sequence of theV β13 gene used by an influenza-specific T cell

1989 • 6 citations

Differentiation in mature T lymphoid leukemia cells is unstable and reversible to myeloid cells, without the involvement of a common stem cell.

1991 • 6 citations

Heterogeneity of T cells specific for a particular peptide/HLA-DQ complex

1994 • 4 citations

Germline sequence of two human T-cell receptor Vβ genes: Vβ8.1 is transcribed from a TATA-box promoter

1987 • 4 citations

Human Tcrb-V6.10 is a pseudogene with Alu repetitive sequences in the promoter region

1993 • 3 citations

The human T-cell receptor 7 (TRG) genes

1989 • 3 citations

A mouse T lymphoma that lacks T-cell receptor surface expression exhibits allelic exclusion of its ? chain genes

1988 • 3 citations

Coding sequence polymorphism of Tcrg-V1, -V2, and -V4 genes in mice bearing Tcr-gA and -gC haplotypes

1994 • 2 citations

Sequence of the TCR β chain gene used by a T cell clone specific for the synthetic polymer, GAT

1990 • 2 citations

Conservation of Tcrg-V5 and limited allelic sequence polymorphism of the other Tcrg-V genes used by mouse tissue-specific gd-T lymphocytes

1996 • 1 citations

Deleted Work

1955 • 0 citations