Silent allelic variants of a T-cell receptor Vβ12 gene are present in diverse human populations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1987 • 5,745 citations

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1989 • 3,557 citations

Sequences of proteins of immunological interest

1984 • 3,427 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Superantigens: Mechanism of T-Cell Stimulation and Role in Immune Responses

1991 • 783 citations

The T Cell Receptor

1987 • 554 citations

Structure, Organization and Polymorphism of Murine and Human T‐Cell Receptor a and β Chain Gene Families

1988 • 448 citations

Multiple mutations in highly conserved residues are found in mildly affected cystic fibrosis patients

1990 • 353 citations

Genes of the T-Cell Antigen Receptor in Normal and Malignant T Cells

1987 • 321 citations

Diversity and structure of human T-cell receptor alpha-chain variable region genes.

1987 • 274 citations

Identification of the region of T cell receptor β chain that interacts with the self-superantigen MIs-1a

1990 • 242 citations

A susceptibility locus for multiple sclerosis is linked to the T cell receptor β chain complex

1989 • 219 citations

Site-directed mutations in the VDJ junctional region of a T cell receptor β chain cause changes in antigenic peptide recognition

1988 • 180 citations

Sequences and diversity of human T cell receptor beta chain variable region genes.

1986 • 140 citations

Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors.

1985 • 122 citations

Vβ17 gene polymorphism in wild-derived mouse strains: Two amino acid substitutions in the Vβ17 region greatly alter T cell receptor specificity

1990 • 122 citations

DNA sequence polymorphisms in Alu repeats

1990 • 111 citations

Segregation of polymorphic T-cell receptor genes in human families.

1985 • 94 citations

Allelic variations in the human T cell receptor V beta 6.7 gene products.

1990 • 85 citations

Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice.

1990 • 69 citations

Allelic sequence variations in the hypervariable region of a T-cell receptor beta chain: correlation with restriction fragment length polymorphism in human families and populations.

1989 • 67 citations

New human V beta genes and polymorphic variants.

1991 • 63 citations

Analysis of a human V beta gene subfamily.

1986 • 63 citations

Insertion/deletion-related polymorphisms in the human T cell receptor beta gene complex.

1989 • 47 citations

Haplotyping the human T-cell receptor beta-chain gene complex by use of restriction fragment length polymorphisms.

1990 • 47 citations

T cell antigen receptors in autoimmunity.

1988 • 46 citations

T-cell receptor genes and insulin-dependent diabetes mellitus (IDDM): no evidence for linkage from affected sib pairs.

1990 • 38 citations

Allelic T-cell receptor α complexes have little or no influence on susceptibility to type 1 diabetes

1989 • 25 citations

Molecular genotyping of human T-cell antigen receptor variable gene segments

1986 • 22 citations

Sequence and expression of a novel human T-cell receptor ?-chain variable gene segment subfamily

1990 • 20 citations

Low frequency of somatic mutation in β-chain variable region genes of human T-cell receptors

1987 • 2 citations