Structure and Diversity of the Human T-Cell Receptor β-Chain Variable Region Genes

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Prediction of protein antigenic determinants from amino acid sequences.

1981 • 3,715 citations

Somatic generation of antibody diversity

1983 • 3,275 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system

1974 • 2,058 citations

AN ANALYSIS OF THE SEQUENCES OF THE VARIABLE REGIONS OF BENCE JONES PROTEINS AND MYELOMA LIGHT CHAINS AND THEIR IMPLICATIONS FOR ANTIBODY COMPLEMENTARITY

1970 • 1,308 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution

1975 • 1,188 citations

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

1981 • 910 citations

Three-Dimensional Structure of Immunoglobulins

1979 • 692 citations

Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes

1974 • 572 citations

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

1984 • 528 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

THE ORGANIZATION, EXPRESSION, AND EVOLUTION OF ANTIBODY GENES AND OTHER MULTIGENE FAMILIES

1975 • 446 citations

Organization and sequences of the diversity, joining, and constant region genes of the human T-cell receptor beta chain.

1985 • 416 citations

Structural Basis of Antibody Function

1983 • 371 citations

The human t cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene

1984 • 306 citations

Murine T-cell receptor mutants with deletions of beta-chain variable region genes.

1986 • 304 citations

The murine T-cell receptor uses a limited repertoire of expressed Vβ gene segments

1985 • 283 citations

The human T cell receptor: Appearance in ontogeny and biochemical relationship of α and β subunits on IL-2 dependent clones and T cell tumors

1983 • 264 citations

Structure, expression and divergence of T-cell receptor β-chain variable regions

1984 • 237 citations

The mouse T cell receptor: Comparison of MHC-restricted receptors on two T cell hybridomas

1983 • 218 citations

The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum

1983 • 217 citations

T-Cell Receptor β-Chain Expression: Dependence on Relatively Few Variable Region Genes

1985 • 197 citations

Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains.

1986 • 143 citations

Sequences and diversity of human T cell receptor beta chain variable region genes.

1986 • 140 citations

Variability and repertoire size of T-cell receptor Vα gene segments

1985 • 131 citations

Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors.

1985 • 122 citations

Genetic Control of Antibody Variable Regions

1977 • 112 citations

Sequence and evolution of the human T-cell antigen receptor beta-chain genes.

1985 • 99 citations

Structural invariants of antigen binding: comparison of immunoglobulin VL-VH and VL-VL domain dimers.

1985 • 79 citations

Partial Primary Structure of the Alpha and Beta Chains of Human Tumor T-Cell Receptors

1985 • 57 citations

Genetic markers of the antigen-specific T cell receptor locus.

1985 • 35 citations