Studies on the human T cell receptor α/β variable region genes. I. Identification of 7 additional V_α subfamilies and 14 J_α gene segments

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Identification of a putative second T-cell receptor

1986 • 980 citations

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

1983 • 833 citations

Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

1988 • 814 citations

Polymerase Chain Reaction with Single-Sided Specificity: Analysis of T Cell Receptor δ Chain

1989 • 640 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

Structure, Organization and Polymorphism of Murine and Human T‐Cell Receptor a and β Chain Gene Families

1988 • 448 citations

A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes

1986 • 430 citations

Rapid cloning of HLA-A,B cDNA by using the polymerase chain reaction: frequency and nature of errors produced in amplification.

1990 • 306 citations

Diversity and structure of human T-cell receptor alpha-chain variable region genes.

1987 • 274 citations

Sequences and repertoire of the human T cell receptor α and β chain variable region genes in thymocytes

1987 • 226 citations

Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor α-chain

1985 • 201 citations

Studies on the human T cell receptor α/β variable region genes. II. Identification of four additional V_β subfamilies

1991 • 148 citations

Sequences and repertoire of human T cell receptor alpha chain variable region genes in mature T lymphocytes.

1986 • 132 citations

Variability and repertoire size of T-cell receptor Vα gene segments

1985 • 131 citations

A unique T-cell receptor complex expressed on human fetal lymphocytes displaying natural-killer-like activity

1986 • 120 citations

Sequence and expression of transcripts of the T-cell antigen receptor alpha-chain gene in a functional, antigen-specific suppressor-T-cell hybridoma.

1986 • 118 citations

Diversity and structure of human T-cell receptor beta-chain variable region genes.

1986 • 112 citations

Human T-cell tumours containing chromosome 14 inversion or translocation with breakpoints proximal to immunoglobulin joining regions at 14q32.

1987 • 75 citations

Deletional rearrangement in the human T-cell receptor alpha-chain locus.

1987 • 68 citations

The human t cell receptor α‐δ locus: a physical map of the variable, joining and constant region genes

1988 • 55 citations

Molecular mechanisms of a t(8;14)(q24;q11) translocation juxtaposing c-myc and TcR-alpha genes in a T-cell leukaemia: involvement of a V alpha internal heptamer.

1988 • 36 citations

Evidence for expression of two distinct T cell receptor beta-chain transcripts in a human diphtheria toxoid-specific T cell clone.

1988 • 29 citations

The antigen receptor of an autoreactive T-cell clone from human rheumatic synovia

1989 • 20 citations