T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

DNA cloning : a practical approach

1985 • 2,302 citations

Patterns of Amino Acids near Signal‐Sequence Cleavage Sites

1983 • 2,290 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

AN ANALYSIS OF THE SEQUENCES OF THE VARIABLE REGIONS OF BENCE JONES PROTEINS AND MYELOMA LIGHT CHAINS AND THEIR IMPLICATIONS FOR ANTIBODY COMPLEMENTARITY

1970 • 1,308 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 772 citations

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.

1982 • 755 citations

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region

1981 • 677 citations

Transfer of specificity by murine α and β T-cell receptor genes

1986 • 568 citations

Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells

1984 • 540 citations

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

1984 • 528 citations

Developmental regulation of T-cell receptor gene expression

1985 • 522 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

Somatic recombination in a murine T-cell receptor gene

1984 • 468 citations

T cell antigen receptors and the immunoglobulin supergene family

1985 • 453 citations

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

1981 • 319 citations

Murine T-cell receptor mutants with deletions of beta-chain variable region genes.

1986 • 304 citations

Expression of T-cell antigen receptor genes during fetal development in the thymus

1985 • 293 citations

The structure, rearrangement and expression of Dβ gene segments of the murine T-cell antigen receptor

1984 • 290 citations

The murine T-cell receptor uses a limited repertoire of expressed Vβ gene segments

1985 • 283 citations

Structure, expression and divergence of T-cell receptor β-chain variable regions

1984 • 237 citations

Diversity and structure of genes of the α family of mouse T-cell antigen receptor

1985 • 228 citations

The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum

1983 • 217 citations

Unusual organization and diversity of T-cell receptor a-chain genes

1985 • 212 citations

The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: Identification of constant and variable peptides

1983 • 209 citations

Somatic mutation of immunoglobulin light-chain variable-region genes

1981 • 184 citations

Rearrangement and transcription of the β-chain genes of the T-cell antigen receptor in different types of murine lymphocytes

1985 • 172 citations

Evolution of immunoglobulin V genes: Evidence indicating that recently duplicated human Vκ sequences have diverged by gene conversion

1983 • 165 citations

Direct evidence for chromosomal inversion during T-cell receptor β-gene rearrangements

1986 • 151 citations

Molecular basis of a mouse strain-specific anti-hapten response

1983 • 150 citations

Variability and repertoire size of T-cell receptor Vα gene segments

1985 • 131 citations

Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors.

1985 • 122 citations

Rearranged β t cell receptor genes in a helper t cell clone specific for lysozyme: No correlation between Vβ and MHC restriction

1985 • 120 citations

Gene conversion and polymorphism: Generation of mouse immunoglobulin γ2a chain alleles by differential gene conversion by γ2b chain gene

1983 • 119 citations

Expression of the T-cell-specific γ gene is unnecessary in T cells recognizing class II MHC determinants

1985 • 68 citations

Allelic exclusion and nonproductive immunoglobulin gene rearrangements

1981 • 68 citations

Rearrangements of DNA mediated by terminal transferase.

1986 • 64 citations

Diversity in the germline antibody repertoire. Molecular evolution of the T15 VN gene family.

1985 • 62 citations

The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype.

1985 • 49 citations

An unusual translocation of immunoglobulin gene segments in variants of the mouse myeloma MPC11

1980 • 40 citations

Alloimmune Cytotoxic T Cells: Evidence that They Recognize Serologically Defined Antigens and Bear Clonally Restricted Receptors

1975 • 39 citations

Isolation of alloreactive CTL clones with cyclical changes in lytic activity.

1983 • 17 citations