MT1‐MMP: A tethered collagenase

New functions for the matrix metalloproteinases in cancer progression

2002 • 5,937 citations

Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations

2002 • 2,711 citations

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

2000 • 2,700 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover

1999 • 1,280 citations

COLLAGENOLYTIC ACTIVITY IN AMPHIBIAN TISSUES: A TISSUE CULTURE ASSAY

1962 • 1,275 citations

Matrix metalloproteinases: a tail of a frog that became a prince

2002 • 1,082 citations

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.

1998 • 887 citations

Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

2000 • 792 citations

Matrilysin Shedding of Syndecan-1 Regulates Chemokine Mobilization and Transepithelial Efflux of Neutrophils in Acute Lung Injury

2002 • 734 citations

The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis

2001 • 699 citations

Membrane Type I Matrix Metalloproteinase Usurps Tumor Growth Control Imposed by the Three-Dimensional Extracellular Matrix

2003 • 659 citations

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

1995 • 620 citations

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

1997 • 612 citations

Matrix Metalloproteinase 9 and Vascular Endothelial Growth Factor Are Essential for Osteoclast Recruitment into Developing Long Bones

2000 • 589 citations

Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice.

1996 • 496 citations

Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK

1998 • 496 citations

Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion

2003 • 402 citations

Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity

1996 • 392 citations

TIMP-2 Is Required for Efficient Activation of proMMP-2 in Vivo

2000 • 383 citations

Matrix metalloproteinases in repair

1999 • 375 citations

Unaltered Secretion of β-Amyloid Precursor Protein in Gelatinase A (Matrix Metalloproteinase 2)-deficient Mice

1997 • 352 citations

Matrix metalloproteinases in arthritic disease.

2002 • 300 citations

In Vivo Evidence That the Stromelysin-3 Metalloproteinase Contributes in a Paracrine Manner to Epithelial Cell Malignancy

1998 • 290 citations

Enamelysin (Matrix Metalloproteinase 20)-deficient Mice Display an Amelogenesis Imperfecta Phenotype

2002 • 267 citations

Identification and Characterization of the Fifth Membrane-type Matrix Metalloproteinase MT5-MMP

1999 • 261 citations

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)

2001 • 243 citations

Impaired Wound Contraction in Stromelysin-1–Deficient Mice

1999 • 232 citations

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)

2001 • 225 citations

Proteolytic Events of Wound-Healing — Coordinated Interactions Among Matrix Metalloproteinases (MMPs), Integrins, and Extracellular Matrix Molecules

2001 • 205 citations

Susceptibility of stromelysin 1-deficient mice to collagen-induced arthritis and cartilage destruction

1998 • 203 citations

Cellular Activation of MMP-2 (Gelatinase A) by MT2-MMP Occurs via a TIMP-2-independent Pathway

2001 • 178 citations

Accelerated apoptosis in the Timp-3–deficient mammary gland

2001 • 164 citations

Identification of Cysteine 354 of β-Tubulin as Part of the Binding Site for the A Ring of Colchicine

1996 • 160 citations

Inactivating Mutation of the Mouse Tissue Inhibitor of Metalloproteinases-2(Timp-2) Gene Alters ProMMP-2 Activation

2000 • 147 citations

Accelerated apoptosis in the Timp-3–deficient mammary gland

2001 • 144 citations

Overexpression of membrane-type matrix metalloproteinase-1 gene induces mammary gland abnormalities and adenocarcinoma in transgenic mice.

2001 • 137 citations

Modulation of matrix metalloproteinase activities in periodontitis as a treatment strategy

2000 • 135 citations

Matrix metalloproteinase deficiencies affect contact hypersensitivity: Stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response

1999 • 131 citations

Mode of growth, fate and functions of cartilage canals.

1970 • 122 citations

On the role of MT1‐MMP, a matrix metalloproteinase essential to collagen remodeling, in murine molar eruption and root growth

2002 • 56 citations

Functional characterization of MT3‐MMP in transfected MDCK cells: progelatinase A activation and tubulogenesis in 3‐D collagen lattice

2000 • 54 citations

Activation of Progelatinase A and Progelatinase A/TIMP-2 Complex by Membrane Type 2-Matrix Metalloproteinase

1997 • 52 citations