Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

Tumor Cell Interactions with the Extracellular Matrix During Invasion and Metastasis

1993 • 1,523 citations

The matrix‐degrading metalloproteinases

1992 • 1,383 citations

Matrix Metalloproteinase-2 Is an Interstitial Collagenase

1995 • 917 citations

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

1995 • 620 citations

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

1995 • 511 citations

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface.

1994 • 494 citations

Identification of the Second Membrane-type Matrix Metalloproteinase (MT-MMP-2) Gene from a Human Placenta cDNA Library

1995 • 474 citations

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: Divergent or shared functions

1994 • 401 citations

A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts.

1993 • 383 citations

Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2

1993 • 338 citations

cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment

1995 • 319 citations

Association Between Expression of Activated 72-Kilodalton Gelatinase and Tumor Spread in Non-Small-Cell Lung Carcinoma

1993 • 278 citations

The C-terminal Region of Membrane Type Matrix Metalloproteinase Is a Functional Transmembrane Domain Required for Pro-gelatinase A Activation

1995 • 269 citations

cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment

1995 • 244 citations

Intermolecular Autolytic Cleavage Can Contribute to the Activation of Progelatinase A by Cell Membranes

1995 • 242 citations

Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3.

1994 • 217 citations

Proprotein-processing endoproteases PC6 and furin both activate hemagglutinin of virulent avian influenza viruses

1994 • 215 citations

Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions.

1992 • 201 citations

Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease.

1992 • 176 citations

Acceptor Specificity of Different Length Constructs of Human Recombinant α1,3/4-Fucosyltransferases

1995 • 153 citations

Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation.

1994 • 151 citations

Accurate and efficient cleavage of the human insulin proreceptor by the human proprotein-processing protease furin. Characterization and kinetic parameters using the purified, secreted soluble protease expressed by a recombinant baculovirus.

1994 • 138 citations

Expression of activated gelatinase in human invasive breast carcinoma

1993 • 135 citations

Preferred sequence requirements for cleavage of pro-von Willebrand factor by propeptide-processing enzymes

1992 • 130 citations

PACE/furin can process the vitamin K-dependent pro-factor IX precursor within the secretory pathway.

1993 • 123 citations

Characterization of a Secreted Form of Human Furin Endoprotease

1993 • 91 citations

Cell surface-mediated activation of progelatinase A: demonstration of the involvement of the C-terminal domain of progelatinase A in cell surface binding and activation of progelatinase A by primary fibroblasts

1994 • 88 citations

Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway

1993 • 66 citations

Comparison of Properties of Membrane Bound Versus Soluble Forms of Human Leukocytic Elastase and Cathepsin G

1994 • 63 citations

A Plasma Membrane-associated Component of Ovarian Adenocarcinoma Cells Enhances the Catalytic Efficiency of Matrix Metalloproteinase-2

1995 • 39 citations

Expression of gelatinase A, a mediator of extracellular matrix remodeling, by tracheal gland serous cells in culture and in vivo.

1994 • 34 citations