In Vivo Evidence That the Stromelysin-3 Metalloproteinase Contributes in a Paracrine Manner to Epithelial Cell Malignancy

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance

1997 • 1,705 citations

Proteoglycans as modulators of growth factor activities

1991 • 1,338 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

Proteolytic remodeling of extracellular matrix

1995 • 1,086 citations

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line

1982 • 727 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

Growth factors in development, transformation, and tumorigenesis

1991 • 695 citations

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

1995 • 620 citations

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

1997 • 612 citations

Matrix metal loproteinases and the development of cancer

1996 • 569 citations

Transgenesis by means of blastocyst-derived embryonic stem cell lines.

1986 • 432 citations

Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis

1995 • 429 citations

Patterns of matrix metalloproteinase expression in cycling endometrium imply differential functions and regulation by steroid hormones.

1994 • 391 citations

Unaltered Secretion of β-Amyloid Precursor Protein in Gelatinase A (Matrix Metalloproteinase 2)-deficient Mice

1997 • 352 citations

Matrix metalloproteinases and tumor invasion: from correlation and causality to the clinic

1996 • 337 citations

Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate

1994 • 323 citations

Thyroid hormone-induced gene expression program for amphibian tail resorption

1993 • 271 citations

Epidermal growth factor or transforming growth factor alpha is required for kidney tubulogenesis in matrigel cultures in serum-free medium.

1990 • 243 citations

Increased stromelysin 3 gene expression is associated with increased local invasiveness in head and neck squamous cell carcinomas.

1993 • 222 citations

Fibroblast cell interactions with human melanoma cells affect tumor cell growth as a function of tumor progression.

1991 • 217 citations

Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3.

1994 • 217 citations

Matrix metalloproteinases as stromal effectors of human carcinoma progression: Therapeutic implications

1997 • 207 citations

Cell Growth and Division

1967 • 187 citations

Neoplastic progression of human colorectal cancer is associated with overexpression of the stromelysin‐3 and BM‐40/SPARC genes

1995 • 174 citations

The breast cancer-associated stromelysin-3 gene is expressed during mouse mammary gland apoptosis.

1992 • 173 citations

Transcriptional Activation of the Matrix Metalloproteinase Gene stromelysin-3 Coincides with Thyroid Hormone-Induced Cell Death during Frog Metamorphosis

1995 • 165 citations

Enhancement of tumorigenicity of human breast adenocarcinoma cells in nude mice by matrigel and fibroblasts

1993 • 146 citations

Breast-Cancer-Associated Stromelysin-3 Gene Is Expressed in Basal Cell Carcinoma and During Cutaneous Wound Healing

1992 • 127 citations

The role of fibroblasts in tumor behavior

1995 • 125 citations

In vivo and in vitro invasiveness of a rat colon‐cancer cell line maintaining E‐cadherin expression: An enhancing role of tumor‐associated myofibroblasts

1994 • 115 citations

High levels of stromelysin-3 correlate with poor prognosis in patients with breast carcinoma

1996 • 107 citations

Stromelysin-3 gene expression in human cancer: an overview.

1994 • 104 citations

Developmental expression of mouse stromelysin-3 mRNA

1995 • 98 citations

Stromelysin-3 expression promotes tumor take in nude mice.

1996 • 92 citations

Correlation between stromelysin‐3 mRNA level and outcome of human breast cancer

1994 • 76 citations

Stromelysin-3: a paradigm for stroma-derived factors implicated in carcinoma progression

1997 • 72 citations

Identification of Structural Determinants Controlling Human and Mouse Stromelysin-3 Proteolytic Activities

1995 • 72 citations

Structure and Promoter Characterization of the Human Stromelysin-3 Gene

1995 • 66 citations

Remodeling MMPIs

1995 • 49 citations

An experimental analysis of cancer: role of ras oncogenes in multistep carcinogenesis.

1990 • 48 citations

Expression of stromelysin-3 in the human placenta and placental bed

1997 • 42 citations

Patent Update Oncologic, Endocrine & Metabolic: Oncologic, Endocrine & Metabolic: Recent advances in the field of matrix metalloproteinase inhibitors

1996 • 37 citations

Mammary tumorigenesis and chemoprevention studies in carcinogen-treated rats

1996 • 35 citations

Characterization of monoclonal antibodies against stromelysin‐3 and their use to evaluate stromelysin‐3 levels in breast carcinoma by semi‐quantitative immunohistochemistry

1995 • 31 citations

Rapid induction of ovarian granulosa cell tumors by 7,12-dimethylbenz(a)anthracene in neonatally estrogenized mice.

1988 • 27 citations

Stromelysin-3 in the biology of the normal and neoplastic mammary gland

1996 • 24 citations

Rat stromelysin 3: cDNA cloning from healing skin wound, activation by furin and expression in rat tissues

1997 • 21 citations