Antibody-induced generation of reactive oxygen radicals by brain macrophages in canine distemper encephalitis: a mechanism for bystander demyelination

Oxygen toxicity, oxygen radicals, transition metals and disease

1984 • 5,301 citations

Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

1988 • 1,371 citations

Oxygen radicals and the nervous system

1985 • 822 citations

Galactocerebroside is a specific cell-surface antigenic marker for oligodendrocytes in culture

1978 • 813 citations

Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells

1987 • 648 citations

Production of superoxide anions by a CNS macrophage, the microglia

1987 • 619 citations

[36] Phagocytic leukocyte oxygenation activities and chemiluminescence: A kinetic approach to analysis

1986 • 462 citations

Degradation of basic protein in myelin by neutral proteases secreted by stimulated macrophages: A possible mechanism of inflammatory demyelination

1978 • 276 citations

Antibody responses in chronic relapsing experimental allergic encephalomyelitis: correlation of serum demyelinating activity with antibody titre to the myelin/oligodendrocyte glycoprotein (MOG)

1987 • 217 citations

Transferrin gene expression visualized in oligodendrocytes of the rat brain by using in situ hybridization and immunohistochemistry.

1985 • 214 citations

Experimental allergic encephalomyelitis: the balance between encephalitogenic T lymphocytes and demyelinating antibodies determines size and structure of demyelinated lesions

1988 • 206 citations

Hypothesis: A role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis

1988 • 199 citations

Experimental models of virus‐induced demyelination of the central nervous system

1982 • 174 citations

Effect of Reactive Oxygen Species on Myelin Membrane Proteins

1985 • 153 citations

Observations on viral demyelinating encephalomyelitis. Canine distemper.

1972 • 125 citations

Methods of Isolation, Purification and Quantitation of Bovine Immunoglobulins

2010 • 105 citations

Lymphocyte-mediated immune cytotoxicity in dogs infected with virulent canine distemper virus

1982 • 101 citations

On the development of CNS lesions in natural canine distemper encephalomyelitis

1976 • 79 citations

Canine distemper virus clearance in chronic inflammatory demyelination

1986 • 78 citations

Serologic Response to Canine Distemper Viral Antigens in Gnotobiotic Dogs Infected with Canine Distemper Virus

1975 • 78 citations

Spread and distribution of viral antigen in nervous canine distemper

1985 • 76 citations

Demyelination in experimental canine distemper virus infection: Immunological, pathologic, and immunohistological studies

1982 • 74 citations

Opsonization with Antimyelin Antibody Increases the Uptake and Intracellular Metabolism of Myelin in Inflammatory Macrophages

1986 • 74 citations

Primary demyelination in experimental canine distemper virus induced encephalomyelitis in gnotobiotic dogs

1982 • 72 citations

Immunological and pathological findings in demyelinating encephalitis associated with canine distemper virus infection

1982 • 64 citations

Myelin-Specific Autoantibodies Associated with Central Nervous System Demyelination in Canine Distemper Virus Infection

1973 • 57 citations

Studies on the intrathecal humoral immune response in canine distemper encephalitis

1986 • 53 citations

Complement potentiates the degradation of myelin proteins by plasmin: Implications for a mechanism of inflammatory demyelination

1986 • 49 citations

Murine Glia Cells in Culture Can be Stimulated to Generate Reactive Oxygen

1987 • 38 citations

Secondary degeneration of oligodendrocytes in canine distemper virus infection in vitro.

1986 • 34 citations

Lymphocyte responsiveness to lectin and myelin antigens in canine distemper infection in relation to the development of demyelinating lesions☆

1983 • 33 citations

Antiviral antibodies stimulate production of reactive oxygen species in cultured canine brain cells infected with canine distemper virus

1989 • 32 citations

Change in the chemiluminescence reactivity pattern during in vitro differentiation of human monocytes to macrophages

1988 • 31 citations

Macrophage Fc receptors control infectivity and neutralization of canine distemper virus-antibody complexes

1984 • 30 citations

Oligodendroglial pathology in canine distemper virus infection in vitro

1987 • 30 citations

Morphological and immunocytochemical characterisation of mixed glial cell cultures derived from neonatal canine brain.

1984 • 30 citations

Production of immunoglobulin G and increased antiviral antibody in cerebrospinal fluid of dogs with delayed-onset canine distemper viral encephalitis

1988 • 27 citations

IDENTIFICATION OF MONONUCLEAR PHAGOCYTES BY INGESTION OF PARTICULATE MATERIALS, SUCH AS ERYTHROCYTES, CARBON, ZYMOSAN, OR LATEX

1981 • 26 citations

Demyelinating, non-demyelinating and attenuated canine distemper virus strains induce oligodendroglial cytolysis in vitro

1987 • 24 citations

Canine distemper and experimental allergic encephalomyelitis in the dog: Comparative patterns of demyelination

1984 • 21 citations

Morphological and immunocytochemical characterisation of mixed glial cell cultures derived from neonatal canine brain

1984 • 19 citations

Demyelinating canine distemper encephalomyelitis: measurement of myelin basic protein in cerebrospinal fluid

1987 • 19 citations

The chemiluminescence activity of peripheral blood mononuclear cells during acute experimental allergic encephalomyelitis

1987 • 6 citations

Immunological Studies in Demyelinating Encephalitis Associated with Vaccinia Virus and Canine Distemper Virus Infection

1983 • 3 citations