A noncholinergic action of acetylcholinesterase (AChE) in the brain: From neuronal secretion to the generation of movement

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

The biology of cholinesterases

1974 • 897 citations

Adenosine 5'-Triphosphate-Sensitive Potassium Channels

1988 • 888 citations

Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry

1988 • 663 citations

Dopamine acts on D2 receptors to increase potassium conductance in neurones of the rat substantia nigra zona compacta.

1987 • 611 citations

Turning behaviour in animals

1980 • 609 citations

Comparison of butyrylcholinesterase and acetylcholinesterase

1989 • 536 citations

The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cells.

1987 • 452 citations

Acetylcholine Mediates a Slow Synaptic Potential in Hippocampal Pyramidal Cells

1983 • 378 citations

Co-localization of acetylcholinesterase and choline acetyltransferase in the rat cerebrum

1983 • 359 citations

Release of dopamine in vivo from cat substantia nigra

1977 • 318 citations

Acetylcholinesterase hydrolyzes substance P

1980 • 306 citations

The substantia nigra of the rat: A golgi study

1977 • 258 citations

A Critique of the Methods Available for the Measurement of Spontaneous Motor Activity

1977 • 254 citations

Antidiabetic sulfonylureas: localization of binding sites in the brain and effects on the hyperpolarization induced by anoxia in hippocampal slices

1989 • 237 citations

Electrophysiology of pars compacta cells in the in vitro substantia nigra—a possible mechanism for dendritic release

1984 • 226 citations

Acetylcholinesterase neurons in dopamine-containing regions of the brain

1975 • 222 citations

Acetylcholinesterase may have novel functions in the brain

1984 • 216 citations

The anatomy of the CNS cholinergic neurons

1984 • 207 citations

Dopaminergic dendrites in the pars reticulata of the rat substantia nigra and their striatal input. combined immunocytochemical localization of tyrosine hydroxylase and anterograde degeneration

1981 • 192 citations

Observations on the fine structure of the substantia nigra in the cat

1970 • 185 citations

Acetylcholinesterase from bovine caudate nucleus is attached to membranes by a novel subunit distinct from those of acetylcholinesterases in other tissues.

1987 • 184 citations

Cholinergic projections to the substantia nigra from the pedunculopontine and laterodorsal tegmental nuclei

1989 • 171 citations

A cholinergic projection to the rat substantia nigra from the pedunculopontine tegmental nucleus

1987 • 168 citations

The nucleus raphe dorsalis of the rat and its projection upon the caudatoputamen. A combined cytoarchitectonic, immunohistochemical and retrograde transport study.

1981 • 166 citations

Facilitation of a dendritic calcium conductance by 5-hydroxytryptamine in the substantia nigra

1988 • 165 citations

Is acetylcholinesterase secreted from central neurons into the cerebrospinal fluid?

1976 • 156 citations

Chemiluminescent determination of acetylcholine, and continuous detection of its release from torpedo electric organ synapses and synaptosomes

1981 • 152 citations

In vivo release of acetylcholinesterase in cat substantia nigra and caudate nucleus

1980 • 127 citations

Dissociable effects of 6-OHDA-induced lesions of neostriatum on anorexia, locomotor activity and stereotypy: The role of behavioural competition

1984 • 108 citations

Isoenzymes of soluble and membrane-bound acetylcholinesterase in bovine splanchnic nerve and adrenal medulla

1975 • 105 citations

ACETYLCHOLINESTERASE IN THE SUBSTANTIA NIGRA AND CAUDATE‐PUTAMEN OF THE RAT: PROPERTIES AND LOCALIZATION IN DOPAMINERGIC NEURONS

1978 • 104 citations

The cholinergic innervation of the rat substantia nigra: a light and electron microscopic immunohistochemical study

1988 • 97 citations

Neurotransmitters in action

1985 • 92 citations

EFFECTS OF SUBSTANCE P INJECTED INTO THE SUBSTANTIA NIGRA

1979 • 92 citations

The cytology of dopaminergic and nondopaminergic neurons in the substantia nigra and ventral tegmental area of the rat: A light- and electron-microscopic study

1983 • 88 citations

The significance of dendritic release of transmitter and protein in the substantia nigra

1985 • 88 citations

Rotatory behavior in rats by intranigral application of substance P and an eledoisin fragment

1977 • 77 citations

Acetylcholinesterase as a marker for dendritic transport and dendritic secretion.

1975 • 75 citations

Conversion of human erythrocyte acetylcholinesterase from an amphiphilic to a hydrophilic form by phosphatidylinositol‐specific phospholipase C and serum phospholipase D

1989 • 74 citations

Release of acetylcholinesterase into the perfusate from the ox adrenal gland

1975 • 73 citations

The influence of electrical stimulation of certain brain regions on the concentration of acetylcholinesterase in rabbit cerebrospinal fluid

1979 • 64 citations

Cholinergic somata and terminals in the rat substantia nigra: An immunocytochemical study with optical and electron microscopic techniques

1989 • 63 citations

The smooth endoplasmic reticulum as a possible storage site for dendritic dopamine in substantia nigra neurones

1979 • 62 citations

Origin of various enzymes released from the substantia nigra and caudate nucleus: Effects of 6‐hydroxydopamine lesions of the nigro‐striatal pathway

1983 • 59 citations

A non-cholinergic function for acetylcholinesterase in the substantia nigra: Behavioural evidence

1984 • 59 citations

Release of acetylcholinesterase and aminopeptidase In vivo following infusion of amphetamine into the substantia nigra

1982 • 57 citations

Determination of acetylcholinesterase activity by a new chemiluminescence assay with the natural substrate

1985 • 53 citations

Ultrastructural localization of acetylcholinesterase in substantia nigra: A comparison between rat and guinea pig

1984 • 51 citations

Acetylcholinesterases: Zymogens of neuropeptide processing enzymes?

1989 • 50 citations

Depression of nigral pars compacta cell discharge by exogenous acetylcholinesterase

1981 • 47 citations

On-line visualization of dendritic release of acetylcholinesterase from mammalian substantia nigra neurons.

1987 • 47 citations

Does the substantia nigra have a cholinergic innervation?

1987 • 41 citations

Electron microscopic localization of cholinergic terminals in the rat substantia nigra: An immunocytochemical study

1989 • 40 citations

Release of acetylcholinesterase from the guinea-pig cerebellum in vivo

1988 • 40 citations

Release of acetylcholinesterase in the rat nigrostriatal pathway: Relation to receptor activation and firing rate

1986 • 39 citations

Cellular biology of ectoenzymes

1987 • 38 citations

Evoked Release of Proteins from Central Neurons In Vivo

1983 • 37 citations

Do nigro-striatal neurones possess a discrete dendritic modulatory mechanism? Electrophysiological evidence from the actions of amphetamine in brain slices

1988 • 36 citations

An electrophysiological action of acetylcholinesterase independent of its catalytic site

1988 • 36 citations

Possible role of acetylcholinesterase in regulation of postsynaptic receptor efficacy at a central inhibitory synapse of Aplysia

1983 • 35 citations

Is the central cholinergic nervous system overexploited?

1969 • 34 citations

Intracellular localization of acetylcholinesterase in nerve terminals and capillaries of the rat superior cervical ganglion

1978 • 31 citations

Properties of Bovine Erythrocyte Acetylcholinesterase Solubilized by Phosphatidylinositol-Specific Phospholipase C1

1987 • 29 citations

Pressure ejection of acetylcholinesterase within the guinea-pig substantia nigra has non-classical actions on the pars compacta cells independent of selective receptor and ion channel blockade

1989 • 28 citations

The induction of ion channels through excitable membranes by acetylcholinesterase

1980 • 26 citations

Acetylcholinesterase has a non-cholinergic neuromodulatory action in the guinea-pig substantia nigra

1987 • 23 citations

Electrophysiological evidence for the dendritic localization of a calcium conductance in guinea-pig substantia nigra neurones in vitro

1989 • 22 citations

Release of acetylcholinesterase from the caudate nucleus of the rat

1987 • 20 citations

Exogenous acetylcholinesterase as tracer for extracellular pathways in the brain

1974 • 20 citations

Measurement of cholinesterase activity released from the brain “on-line” and in vivo

1989 • 20 citations

Spontaneous and carbachol-evoked in vivo secretion of acetylcholinesterase from the hippocampus of the rat

1987 • 19 citations

Application of acetylcholinesterase to the substantia nigra induces stereotypy in rats

1985 • 19 citations

A possible ionic basis for dendritic release of dopamine in the guinea‐pig substantia nigra

1989 • 18 citations

6-Hydroxydopamine-induced turning behaviour in the rat: The significance of acetylcholinesterase in cerebrospinal fluid

1986 • 16 citations

SYNTHESIS, ASSEMBLY, AND PROCESSING OF AChE IN TISSUE CULTURED MUSCLE

1984 • 15 citations

Release of acetylcholinesterase within the guinea-pig substantia nigra: Efects of 5-hydroxytryptamine and amphetamine

1988 • 14 citations

Ultrastructural localization of acetylcholinesterase activity in primary cultures of rat substantia nigra

1980 • 13 citations

Acetylcholinesterase activity rises in rat cerebrospinal fluid post‐ictally; effect of a substantia nigra lesion on this rise and on seizure threshold

1987 • 12 citations

Release of acetylcholinesterase from the guinea-pig substantia nigra during peripheral nerve stimulation

1989 • 10 citations

Pulsatile release of acetylcholinesterase from the substantia nigra following electrical stimulation of the striatum

1989 • 8 citations

A NOVEL FUNCTION FOR ACETYLCHOLINESTERASE IN NIGRO-STRIATAL NEURONS

1984 • 6 citations

Can Enzymes Released from the Nigro-Striatal Pathway Act as Neuromodulators?

1984 • 2 citations