Members of a nicotinic acetylcholine receptor gene family are expressed in different regions of the mammalian central nervous system

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Patterns of Amino Acids near Signal‐Sequence Cleavage Sites

1983 • 2,290 citations

Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes

1984 • 1,638 citations

Rapid similarity searches of nucleic acid and protein data banks.

1983 • 1,577 citations

Use of Helical Wheels to Represent the Structures of Proteins and to Identify Segments with Helical Potential

1967 • 1,178 citations

A putative signal peptidase recognition site and sequence in eukaryotic and prokaryotic signal peptides

1983 • 1,143 citations

A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: Application to sequencing the corn mitochondrial 18 S rDNA

1985 • 1,051 citations

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin

1985 • 1,037 citations

Distribution of cholinergic neurons in rat brain: Demonstrated by the immunocytochemical localization of choline acetyltransferase

1983 • 964 citations

Efferent connections of the habenular nuclei in the rat

1979 • 824 citations

Afferent connections of the habenular nuclei in the rat. A horseradish peroxidase study, with a note on the fiber-of-passage problem

1977 • 769 citations

Organization and morphological characteristics of cholonergic neurons: an immunocytochemical study with a monoclonal antibody to choline acetyltransferase

1983 • 745 citations

Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor.

1984 • 513 citations

Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor α-subunit

1986 • 444 citations

Cloning and sequence analysis of calf cDNA and human genomic DNA encoding α-subunit precursor of muscle acetylcholine receptor

1983 • 433 citations

Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization

1986 • 414 citations

Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site.

1984 • 408 citations

Purification and characterization of a nicotinic acetylcholine receptor from rat brain.

1987 • 300 citations

A structural model of the acetylcholine receptor channel based on partition energy and helix packing calculations

1984 • 260 citations

Stimulation of nigrostriatal dopamine neurones by nicotine

1982 • 232 citations

Alpha-bungarotoxin binding and central nervous system nicotinic acetylcholine receptors

1981 • 219 citations

alpha-Bungarotoxin binding and cholinergic receptor function on a rat sympathetic nerve line

1977 • 210 citations

Immunological distinction between acetylcholine receptor and the alpha-bungarotoxin-binding component on sympathetic neurons.

1977 • 199 citations

Denervation supersensitivity in skeletal muscle: analysis with a cloned cDNA probe.

1984 • 191 citations

Organization of choline acetyltransferase-containing structures in the forebrain of the rat

1986 • 174 citations

Isolation of a clone coding for the alpha-subunit of a mouse acetylcholine receptor

1985 • 169 citations

Purification and characterization of a nicotinic acetylcholine receptor from chick brain

1986 • 167 citations

Brain and muscle nicotinic acetylcholine receptors are different but homologous proteins.

1985 • 154 citations

Determination of the primary amino acid sequence specifying the alpha-bungarotoxin binding site on the alpha subunit of the acetylcholine receptor from Torpedo californica.

1985 • 146 citations

Mapping of the alpha-bungarotoxin binding site within the alpha subunit of the acetylcholine receptor.

1986 • 139 citations

Primary structure of a developmentally regulated nicotinic acetylcholine receptor protein from Drosophila

1986 • 139 citations

Mapping of brain areas expressing RNA homologous to two different acetylcholine receptor alpha-subunit cDNAs.

1986 • 112 citations

Immunohistochemical localization of monoclonal antibodies to the nicotinic acetylcholine receptor in chick midbrain.

1983 • 105 citations

Channel properties of an insect neuronal acetylcholine receptor protein reconstituted in planar lipid bilayers

1986 • 99 citations

Muscle denervation increases the levels of two mRNAs coding for the acetylcholine receptor alpha-subunit

1985 • 93 citations

Characterization of a component in chick ciliary ganglia that cross- reacts with monoclonal antibodies to muscle and electric organ acetylcholine receptor

1985 • 88 citations

Enhancement of [3H]dopamine release and its [3H]metabolites in rat striatum by nicotinic drugs

1982 • 86 citations

Evolutionary links between apposition and superposition optics in crustacean eyes

1983 • 80 citations

Segment α 182‐198 of Torpedo californica acetylcholine receptor contains a second toxin‐binding region and binds anti‐receptor antibodies

1986 • 75 citations

Variation in the polyadenylylation site of bovine prolactin mRNA.

1982 • 63 citations

The action of cholinomimetic substances on impulse conduction in the habenulointerpeduncular pathway of the rat in vitro.

1984 • 62 citations

The cortical relationships of certain basal ganglia and the cholinergic basal forebrain nuclei

1983 • 54 citations

Spread of acetylcholine sensitivity in the neocortex following lesion of the nucleus basalis

1982 • 41 citations

Nicotinic acetylcholine receptor : structure and function

1986 • 39 citations

Neurochemical identification of cholinergic forebrain projection sites of the nucleus tegmentalis dorsalis lateralis

1981 • 35 citations

Characterization of putative nicotinic acetylcholine receptors solubilized from rat brains

1986 • 28 citations

Analysis of acetylcholine receptor phosphorylation sites using antibodies to synthetic peptides and monoclonal antibodies.

1986 • 25 citations

Nicotine Receptors in the Central Nervous System

1986 • 25 citations