Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine

Endogenous opioid peptides: multiple agonists and receptors

1977 • 2,494 citations

Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.

1973 • 1,272 citations

Catecholamine innervation of the basal forebrain IV. Topography of the dopamine projection to the basal forebrain and neostriatum

1978 • 1,160 citations

Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

1982 • 1,160 citations

The immunocytochemical localization of enkephalin in the central nervous system of the rat

1981 • 553 citations

Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity

1978 • 550 citations

Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography.

1980 • 463 citations

Catecholamines: Basic and clinical frontiers

1981 • 458 citations

Time‐dose relationships for locomotor activity effects of morphine after acute or repeated treatment

1972 • 439 citations

Comparison of Effects of L-Dopa, Amphetamine and Apomorphine on Firing Rate of Rat Dopaminergic Neurones

1973 • 436 citations

Immunohistochemical mapping of enkephalin containing cell bodies, fibers and nerve terminals in the brain stem of the rat

1979 • 382 citations

Immunocytochemical Localization of β-Endorphin-Containing Neurons in the Rat Brain

1981 • 380 citations

The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat

1979 • 354 citations

Heroin reward is dependent on a dopaminergic substrate

1981 • 333 citations

Attenuation of heroin reward in rats by disruption of the mesolimbic dopamine system

1983 • 309 citations

Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study.

1977 • 299 citations

Comparison of the Distribution of Dynorphin Systems and Enkephalin Systems in Brain

1982 • 278 citations

Immunohistochemical localization of enkephalin in rat forebrain

1980 • 267 citations

Nigral Dopamine Neurons: Intracellular Recording and Identification with L-Dopa Injection and Histofluorescence

1980 • 239 citations

The role of dopamine in maintaining intracranial self-stimulation in the ventral tegmentum, nucleus accumbens, and medial prefrontal cortex.

1978 • 211 citations

Stimulant effects of enkephalin microinjection into the dopaminergic A10 area

1979 • 178 citations

Morphine Lowering of Self-Stimulation Thresholds: Lack of Tolerance with Long-Term Administration

1977 • 171 citations

Immunohistochemical distribution of alpha-neo-endorphin/dynorphin neuronal systems in rat brain: evidence for colocalization.

1982 • 166 citations

Effects of morphine and haloperidol on the electrical activity of rat nigrostriatal neurons.

1977 • 149 citations

Evidence that dynorphin-(1–13) acts as an agonist on opioid κ-receptors

1982 • 131 citations

Centrally acting peptides

1979 • 127 citations

A topographic localization of enkephalin on the dopamine neurons of the rat substantia nigra and ventral tegmental area demonstrated by combined histofluorescence-immunocytochemistry

1980 • 121 citations

On the significance of regional dopamine metabolism in the rat brain for the classification of centrally acting drugs

1977 • 117 citations

Operant analysis of human heroin self-administration and the effects of naltrexone.

1981 • 106 citations

Brain substrates for reinforcement and drug self-administration

1981 • 105 citations

Electrophysiological examination of the ventral tegmental (A10) area in the rat

1980 • 100 citations

Dopaminergic neurons: Effect of acute and chronic morphine administration on single cell activity and transmitter metabolism

1978 • 95 citations

Localization of opiate receptors in substantia nigra evidence by lesion studies

1979 • 87 citations

Morphine differentially alters synthesis and turnover of dopamine in central neuronal systems

1980 • 82 citations

Morphine differentially affects ventral tegmental and substantia nigra brain reward thresholds

1981 • 78 citations

cellular responses to electrophoretically applied dynorphin in the rat hippocampus

1982 • 49 citations

Actions of substance P and opiates in the rat substantia nigra

1982 • 47 citations

Immunohistochemical localization of peptides in the nervous system

1978 • 44 citations

Electrophysiological effects of opiates and opioid peptides

1978 • 29 citations

Differential effect of morphine on dopaminergic neurons in frontal cortex and striatum of the rat

1976 • 25 citations

The participation of substantia nigra zona compacta and zona reticulata neurons in morphine suppression of caudate spontaneous neuronal activities in the rat

1981 • 17 citations

OPIOID AGONISTS AND ANTAGONISTS: ACTION ON MULTIPLE OPIATE RECEPTORS

1980 • 13 citations

EFFECTS OF OPIATES ON NIGROSTRIATAL DOPAMINERGIC ACTIVITY: ELECTROPHYSIOLOGICAL AND BEHAVIORAL ANALYSES

1979 • 12 citations