Selective dopamine antagonists reduce nicotine self-administration

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats

1986 • 693 citations

The pharmacology of cocaine related to its abuse.

1989 • 685 citations

Nicotine maintains robust self-administration in rats on a limited-access schedule

1989 • 586 citations

Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems

1982 • 560 citations

Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons

1985 • 527 citations

Nicotinic effects on the firing pattern of midbrain dopamine neurons

1986 • 399 citations

Evidence that mesolimbic dopaminergic activation underlies the locomotor stimulant action of nicotine in rats.

1988 • 313 citations

Nicotinic excitation of rat ventral tegmental neurones in vitro studied by intracellular recording

1989 • 291 citations

The D1 dopamine receptor antagonist SCH 23390 increases cocaine self-administration in the rat

1987 • 281 citations

Preferential stimulation of ventral tegmental area dopaminergic neurons by nicotine

1987 • 275 citations

Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis

1989 • 193 citations

Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by Rhesus monkeys

1986 • 177 citations

Locomotor activity in rats after administration of nicotinic agonists intracerebrally

1990 • 158 citations

The effects of a D1 and a D2 dopamine antagonist on behavior maintained by cocaine or food

1989 • 131 citations

Control of sensorimotor function by dopaminergic nigrostriatal neurons: Influence on eating and drinking

1986 • 82 citations

Effects of dopaminergic nucleus accumbens lesions on the acquisition of schedule induced self injection of nicotine in the rat

1982 • 78 citations

Locomotion induced by ventral tegmental microinjections of a nicotinic agonist

1990 • 64 citations

Action of nicotine on accumbens dopamine and attenuation with repeated administration

1989 • 60 citations

Interaction of nicotine with dopaminergic mechanisms assessed through drug discrimination and rotational behaviour in rats

1987 • 45 citations

A Rodent Model for Nicotine Self-Administration

2003 • 41 citations

Effect of dopamine agents on schedule- and deprivation-induced drinking in rats

1987 • 31 citations

Effects of 6-OHDA lesions in the nucleus accumbens on the acquisition of self injection of heroin under schedule and non schedule conditions in rats

1984 • 21 citations

Effects of opiate antagonist treatment into either the periaqueductal grey or nucleus accumbens on heroin-induced locomotor activation

1987 • 19 citations

Effect of (-) and (+) nicotine of [3H]DA uptake and release in rat striatum.

1990 • 3 citations