Ultrastructural single‐ and double‐label immunohistochemical studies of substance P‐containing terminals and dopaminergic neurons in the substantia nigra in pigeons

The functional anatomy of basal ganglia disorders

1989 • 5,166 citations

Primate models of movement disorders of basal ganglia origin

1990 • 3,722 citations

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system

1970 • 1,980 citations

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1975 • 1,741 citations

Efferent connections and nigral afferents of the nucleus accumbens septi in the rat

1978 • 868 citations

Tyrosine hydroxylase-immunoreactive boutons in synaptic contact with identified striatonigral neurons, with particular reference to dendritic spines

1984 • 866 citations

The neostriatal mosaic: compartmentalization of corticostriatal input and striatonigral output systems

1984 • 815 citations

Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain.

1986 • 744 citations

Progress in Brain Research.

1965 • 738 citations

Dendritic release of dopamine in the substantia nigra

1981 • 732 citations

Distribution of striatonigral and striatopallidal peptidergic neurons in both patch and matrix compartments: an in situ hybridization histochemistry and fluorescent retrograde tracing study

1988 • 649 citations

Self-inhibition by Dopaminergic Neurons

1975 • 645 citations

Release of dopamine from dendrites in rat substantia nigra

1976 • 644 citations

Detection of substance P in the central nervous system by a monoclonal antibody.

1979 • 594 citations

Efferent projections of the subthalamic nucleus in the rat: Light and electron microscopic analysis with the PHA‐L method

1987 • 580 citations

An Autoradiographic Analysis of the Efferent Connections from Premotor and Adjacent Prefrontal Regions (Areas 6 and 9) in <i>Macaca fascicularis</i>; pp. 185–209

1978 • 556 citations

The neostriatal mosaic. I. compartmental organization of projections from the striatum to the substantia nigra in the rat

1985 • 549 citations

Organization of the efferent projections of the nucleus accumbens to pallidal, hypothalamic, and mesencephalic structures: A tracing and immunohistochemical study in the cat

1984 • 453 citations

Optimization of differential immunogold-silver and peroxidase labeling with maintenance of ultrastructure in brain sections before plastic embedding

1990 • 450 citations

Comparison of Effects of L-Dopa, Amphetamine and Apomorphine on Firing Rate of Rat Dopaminergic Neurones

1973 • 436 citations

Two cell types in rat substantia nigra zona compacta distinguished by membrane properties and the actions of dopamine and opioids

1989 • 426 citations

Altered Tonic Activity of Neurons in the Globus Pallidus and Subthalamic Nucleus in the Primate MPTP Model of Parkinsonism

1987 • 420 citations

Immunohistochemical studies on the localization and distribution of monoamine neuron systems in the rat brain. I. Tyrosine hydroxylase in the mes- and diencephalon.

1976 • 394 citations

The afferent and efferent connections of the feline nucleus tegmenti pedunculopontinus, pars compacta

1983 • 380 citations

Glutamate decarboxylase immunoreactive neurons in rat neostriatum: their morphological types and populations

1988 • 365 citations

Comparison of fixation and penetration enhancement techniques for use in ultrastructural immunocytochemistry.

1983 • 349 citations

Evidence for the existence of substance P-containing fibres in striato-nigral and pallido-nigral pathways in rat brain

1977 • 334 citations

Ultrastructural immunocytochemical localization of tyrosine hydroxylase in the neostriatum

1981 • 332 citations

Direct chemical stimulation of dopaminergic mechanisms in the neostriatum of the rat

1969 • 331 citations

An approach to tracing neuron networks in the cerebral cortex and basal ganglia. Combination of golgi staining, retrograde transport of horseradish peroxidase and anterograde degeneration of synaptic boutons in the same material

1979 • 329 citations

Neurons of the subthalamic nucleus in primates display glutamate but not GABA immunoreactivity

1988 • 326 citations

Comparative neurobiology of the basal ganglia

1986 • 312 citations

The identification of striatal and pallidal neurons projecting to substantia nigra

1975 • 309 citations

Efferent projections of the subthalamic nucleus in the squirrel monkey as studied by the PHA‐L anterograde tracing method

1990 • 288 citations

Turning in circles: The neuropharmacology of rotation

1976 • 286 citations

The organization and projections of the paleostriatal complex in the pigeon (columba livia)

1973 • 285 citations

Opposing effects of striatonigral feedback pathways on midbrain dopamine cell activity

1985 • 279 citations

Topographic organization of the ventral striatal efferent projections in the rhesus monkey: An anterograde tracing study

1990 • 277 citations

Projections of the pedunculopontine tegmental nucleus in the rat: evidence for additional extrapyramidal circuitry

1982 • 277 citations

The patterns of neurotransmitter and neuropeptide co-occurrence among striatal projection neurons: conclusions based on recent findings

1990 • 276 citations

The glutamate decarboxylase-, leucine enkephalin-, methionine enkephalin-and substance P-immunoreactive neurons in the neostriatum of the rat and cat: Evidence for partial population overlap

1986 • 276 citations

Comparative distribution of dopamine D‐1 and D‐2 receptors in the basal ganglia of turtles, pigeons, rats, cats, and monkeys

1987 • 265 citations

Topographic projections of substance P and GABA pathways in the striato- and pallido-nigral system: A biochemical and immunohistochemical study

1978 • 264 citations

Evolution of the amniote basal ganglia

1984 • 259 citations

The GABA and substance P input to dopaminergic neurones in the substantia nigra of the rat

1990 • 254 citations

Projections of substance P containing neurons from neostriatum to substantia nigra

1977 • 249 citations

Dopamine release in substantia nigra?

1976 • 249 citations

First demonstration of highly specific and sensitive antibodies against dopamine

1984 • 248 citations

A hypothesis on the pathophysiological mechanisms that underlie levodopa‐ or dopamine agonist‐induced dyskinesia in Parkinson's disease: Implications for future strategies in treatment

1990 • 244 citations

A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride.

1986 • 234 citations

Dorsal raphe cells with collateral projections to the caudate-putamen and substantia nigra: A fluorescent retrograde double labeling study in the rat

1980 • 231 citations

Dopamine selectively increases 3H-GABA release from slices of rat substantia nigra in vitro

1977 • 218 citations

Synaptic mechanisms in the substantia nigra

1976 • 217 citations

The output neurones and the dopaminergic neurones of the substantia nigra receive a GABA‐Containing input from the globus pallidus in the rat

1990 • 215 citations

Demonstration of a pallido‐nigral projection innervating dopaminergic neurons

1975 • 207 citations

Anatomy and Physiology of the Subthalamic Nucleus: A Driving Force of the Basal Ganglia

1987 • 206 citations

Monosynaptic input from the nucleus accumbens-ventral striatum region to retrogradely labelled nigrostriatal neurones

1981 • 204 citations

Evidence that L-dopa-induced rotational behavior is dependent on both striatal and nigral mechanisms

1989 • 197 citations

Evidence for the coexistence of glutamate decar☐ylase and Met-enkephalin immunoreactivities in axon terminals of rat ventral pallidum

1985 • 196 citations

Electrophysiological analysis of reciprocal caudato-nigral relations

1967 • 194 citations

Innervation of substantia nigra neurons by cholinergic afferents from pedunculopontine nucleus in the rat: neuroanatomical and electrophysiological evidence

1987 • 194 citations

Dopaminergic dendrites in the pars reticulata of the rat substantia nigra and their striatal input. combined immunocytochemical localization of tyrosine hydroxylase and anterograde degeneration

1981 • 192 citations

Extensive co‐occurrence of substance P and dynorphin in striatal projection neurons: An evolutionarily conserved feature of basal ganglia organization

1990 • 187 citations

Amygdalonigral pathway: An anterograde study in the rat with Phaseolus vulgaris leucoagglutinin (PHA‐L)

1990 • 174 citations

Striato-nigral dynorphin and substance P pathways in the rat

1986 • 171 citations

Cholinergic projections to the substantia nigra from the pedunculopontine and laterodorsal tegmental nuclei

1989 • 171 citations

A cholinergic projection to the rat substantia nigra from the pedunculopontine tegmental nucleus

1987 • 168 citations

Localization of immunoreactive enkephalins in GABA synthesizing neurons of the rat neostriatum

1984 • 167 citations

Cellular localization of monoamines in the upper brain stem of the pigeon

1965 • 166 citations

Dopaminergic neurons of the substantia nigra modulate preproenkephalin A gene expression in rat striatal neurons

1988 • 159 citations

Dopamine Modulation of the Effects of γ-Aminobutyric Acid on Substantia Nigra Pars Reticulata Neurons

1983 • 158 citations

Substance P: Localization within paleostriatal-tegmental pathways in the pigeon

1983 • 153 citations

Effects of intranigral application of dopamine and substance P on the in vivo release of newly synthesized [3H]-dopamine in the ipsilateral caudate nucleus of the cat

1977 • 152 citations

Two-color immunohistochemistry for dopamine and GABA neurons in rat substantia nigra and zona incerta

1982 • 149 citations

Interactions between neuropeptides and dopamine neurons in the ventromedial mesencephalon

1985 • 148 citations

Electrophysiologically identified nigral dopaminergic neurons intracellularly labeled with HRP: light-microscopic analysis

1987 • 140 citations

Differential modulation of striatal dopamine release by intranigral injection of γ-aminobutyric acid (GABA), dynorphin A and substance P

1988 • 133 citations

Prosencephalic pathways related to the paleostriatum of the pigeon (Columba livia)

1978 • 130 citations

Projections of the paleostriatum upon the midbrain tegmentum in the pigeon

1981 • 126 citations

Topography of substantia nigra innervation by D1 receptor-containing striatal neurons

1987 • 124 citations

Comparative neurobiology of the basal ganglia

1987 • 123 citations

The fine structure of the neurons in the rat surstantia nigra

1971 • 123 citations

Rotational behavior induced in rats by intranigral application of GABA-related drugs and GABA antagonists

1977 • 121 citations

Local cerebral glucose utilization in monkeys with hemiparkinsonism induced by intracarotid infusion of the neurotoxin MPTP

1990 • 121 citations

Distribution of mu, delta, and kappa opiate receptor types in the forebrain and midbrain of pigeons

1989 • 118 citations

Evidence for substance P in the striato-nigral tract

1977 • 115 citations

Striato-nigral dynorphin and substance P pathways in the rat

1986 • 113 citations

Basal ganglia pathways to the tectum: The afferent and efferent connections of the lateral spiriform nucleus of pigeon

1982 • 113 citations

The monoamine‐containing neurons in avian brain: I. A study of the brain stem of the chicken (Gallus domesticus) by means of fluorescence and acetylcholinesterase histochemistry

1981 • 112 citations

Feline subthalamic nucleus neurons contain glutamate-like but not GABA-like or glycine-like immunoreactivity

1989 • 109 citations

Opioid peptide-like immunoreactivity localized in GABAergic neurons of rat neostriatum and central amygdaloid nucleus

1983 • 107 citations

The influence of striatal stimulation and putative neurotransmitters on identified neurones in the rat substantia nigra

1981 • 104 citations

Autoradiographic localization of neuroleptic and dopamine receptors in the caudate-putamen and substantia nigra: Effects of lesions

1979 • 102 citations

Telencephalic projections from midbrain and isthmal cell groups in the pigeon. II. The nigral complex

1986 • 101 citations

Dissociation between the presynaptic dopamine-sensitive adenylate cyclase and [3H]spiperone binding sites in rat substantia nigra

1979 • 100 citations

Electron microscopic localization of neurotensin binding sites in the midbrain tegmentum of the rat. I. Ventral tegmental area and the interfascicular nucleus

1989 • 98 citations

Synaptic connections of substance P-immunoreactive nerve terminals in the substantia nigra of the rat

1982 • 97 citations

The cholinergic innervation of the rat substantia nigra: a light and electron microscopic immunohistochemical study

1988 • 97 citations

Substance P and neurokinin A regulate by different mechanisms dopamine release from dendrites and nerve terminals of the nigrostriatal dopaminergic neurons

1988 • 94 citations

Association of dopamine d, and d2 receptors with specific cellular elements in the basal ganglia of the cat: The uneven topography of dopamine receptors in the striatum is determined by intrinsic striatal cells, not nigrostriatal axons

1988 • 91 citations

Opposite effects of μ and κ opiates on the firing-rate of dopamine cells in the substantia nigra of the rat

1987 • 90 citations

The cytology of dopaminergic and nondopaminergic neurons in the substantia nigra and ventral tegmental area of the rat: A light- and electron-microscopic study

1983 • 88 citations

Distribution and relative abundance of neurons in the pigeon forebrain containing somatostatin, neuropeptide Y, or both

1990 • 87 citations

The striatonigral projection and nigrotectal neurons in the rat. A correlated light and electron microscopic study demonstrating a monosynaptic striatal input to identified nigrotectal neurons using a combined degeneration and horseradish peroxidase procedure

1985 • 84 citations

Substance K excites dopaminergic and non-dopaminergic neurons in rat substantia nigra

1985 • 84 citations

Striatonigral projection neurons: A retrograde labeling study of the percentages that contain substance P or enkephalin in pigeons

1991 • 81 citations

Immunohistochemical and biochemical studies on Lys⁸‐Asn⁹‐neurotensin^8–13(LANT6)‐related peptides in the basal ganglia of pigeons, turtles, and hamsters

1987 • 79 citations

Immunocytochemical demonstration of GABAergic synaptic connections in rat substantia nigra after different lesions of the striatonigral projection

1988 • 78 citations

Modulation of striatal enkephalinergic neurons by antipsychotic drugs.

1985 • 77 citations

Rotatory behavior in rats by intranigral application of substance P and an eledoisin fragment

1977 • 77 citations

Efferent connections of the dorsal tegmental region in the rat, studied by means of anterograde transport of the lectin Phaseolus vulgaris-leucoagglutinin (PHA-L)

1984 • 76 citations

Different neuronal location of [3H]SCH 23390 binding sites in pars reticulata and pars compacta of the substantia nigra in the rat

1986 • 75 citations

Behavioural and biochemical effects of substance P injected into the substantia nigra of the rat

1977 • 75 citations

GABA‐like immunoreactivity of neurons in the chicken diencephalon and mesencephalon

1989 • 74 citations

Demonstration of the existence of small local circuit neurons in the Golgi-stained primate substantia nigra

1979 • 71 citations

A morphological evidence for monosynaptic projections from the nucleus tegmenti pedunculopontinus pars compacta (TPC) to nigrostriatal projection neurons

1988 • 71 citations

The co-occurrence of substance P-like immunoreactivity and dynorphin-like immunoreactivity in striatopallidal and striatonigral projection neurons in birds and reptiles

1986 • 68 citations

Effect of intranigral injections of dynorphin, dynorphin fragments and α-neoendorphin on rotational behaviour in the rat

1984 • 63 citations

Immunocytochemical evidence for direct connections between neurotensin-containing axons and dopaminergic neurons in the rat ventral midbrain tegmentum

1989 • 63 citations

Anatomical study of enkephalin gene expression in the rat forebrain following haloperidol treatment

1987 • 58 citations

Immunoreactive substance P in the substantia nigra of the monkey: light and electron microscopic localization

1982 • 58 citations

Computer measurements of axis cylinder diameters of radial fibers and “comb” bundle fibers

1975 • 58 citations

Differential sensitivity of presumed dopaminergic and non-dopaminergic neurones in rat substantia nigra to electrophoretically applied substance P

1982 • 52 citations

The neurophysiologic basis of abnormal movements in basal ganglia disorders.

1983 • 52 citations

Substance P-dopamine relationship in the rat substantia nigra: a light and electron microscopy study of double immunocytochemically labeled materials

1988 • 51 citations

Localization of dopamine receptors in rat brain

1979 • 50 citations

Biphasic and Opposite Effects of Dopamine and Apomorphine on Endogenous GABA Release in the Rat Substantia Nigra

1980 • 49 citations

Distribution of substance P in the pigeon brain

1978 • 48 citations

Neurotransmitter receptors in the avian brain. III. GABA-benzodiazepine receptors

1988 • 48 citations

Actions of substance P and opiates in the rat substantia nigra

1982 • 47 citations

In vivo release of substance P in the cat substantia nigra

1979 • 46 citations

Benzidine dihydrochloride as a chromogen for single- and double-label light and electron microscopic immunocytochemical studies.

1986 • 45 citations

Electrophysiological changes in substantia nigra after dynorphin administration

1986 • 43 citations

Nigrostriatal dopamine neurons receive substance P-ergic inputs in the substantia nigra: application of the immunoelectron microscopic mirror technique to fluorescent double-staining for transmitter-specific projections

1987 • 40 citations

Ultrastructural basis for interactions between central opioids and catecholamines. II. Nuclei of the solitary tracts

1989 • 40 citations

A VIP-like peptide co-occurs with substance P and enkephalin in cholinergic preganglionic terminals of the avian ciliary ganglion

1987 • 40 citations

Apomorphine pecking in the pigeon.

1975 • 36 citations

Neuropeptides in striato-nigral pathways

1981 • 36 citations

Evidence that nigral substance P controls the activity of the nigrotectal GABAergic pathway

1984 • 33 citations

Direct demonstration of interactions between substance P immunoreactive terminals and tyrosine hydroxylase immunoreactive neurons in the substantia nigra of the rat: An ultrastructural study

1988 • 29 citations

Presence and Ontogeny of Enkephalin and Substance P in the Chick Ciliary Ganglion

1985 • 27 citations

The TPc, the avian substantia nigra: Pharmacology and behavior

1982 • 27 citations

Contralateral circling behavior induced by intranigral microinjections of taurine and GABA in rats

1985 • 26 citations

6-Hydroxydopamine lesions reduce specific [3H]sulpiride binding in the rat substantia nigra: direct evidence for the existence of nigral D-2 autoreceptors

1987 • 25 citations

Substance P synaptic interactions with GABAergic and dopaminergic neurons in rat substantia nigra: An ultrastructural doublelabeling immunocytochemical study

1992 • 21 citations

Differential Effects of Tachykinins Injected Intranigrally on Striatal Dopamine Metabolism

1988 • 19 citations

Substance K (NKA) increases tyrosine hydroxylase mRNA in cultured substantia nigra

1988 • 17 citations

Dopamine-independent motor behavior following microinjection of rimorphin in the substantia nigra

1988 • 16 citations

Chapter 3 Physiology of peptides in basal ganglia

1986 • 14 citations

Intranigral injection of dynorphin in combination with substance P on striatal dopamine metabolism in the rat

1988 • 14 citations

Dopamine D1 heteroreceptors on striatonigral axons are not stimulated by endogeneous dopamine either tonically or after amphetamine: evidence from terminal excitability

1989 • 13 citations

Tegmentonigral projection in the cat: electron microscopic observations.

1984 • 12 citations

Intraspinal substance p-containing projections to the sympathetic preganglionic neuropil in pigeon, Columba livia: High-performance liquid chromatography, radioimmunoassay and electron microscopic evidence

1988 • 11 citations

Dopaminergic terminals in the rat locus coeruleus: an immunocytochemical investigation

1988 • 9 citations

Immunohistochemical detection of GTP-binding regulatory protein (Go) in the autonomic nervous system including the enteric nervous system, superior cervical ganglion and adrenal medulla

1988 • 5 citations