Inhibition of Mcm4,6,7 Helicase Activity by Phosphorylation with Cyclin A/Cdk2

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1994 • 902 citations

Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase

1997 • 743 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

A DNA Helicase Activity Is Associated with an MCM4, -6, and -7 Protein Complex

1997 • 539 citations

Loading of an Mcm Protein onto DNA Replication Origins Is Regulated by Cdc6p and CDKs

1997 • 503 citations

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

1997 • 496 citations

Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

1991 • 493 citations

Phosphorylation of mammalian CDC6 by Cyclin A/CDK2 regulates its subcellular localization

1999 • 416 citations

A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication

1993 • 400 citations

INITIATION OF DNA REPLICATION IN EUKARYOTIC CELLS

1997 • 399 citations

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

1994 • 393 citations

CLB5: a novel B cyclin from budding yeast with a role in S phase.

1992 • 391 citations

The Xenopus Cdc6 Protein Is Essential for the Initiation of a Single Round of DNA Replication in Cell-Free Extracts

1996 • 387 citations

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state

1995 • 366 citations

Purification of an MCM-containing complex as a component of the DNA replication licensing system

1995 • 361 citations

Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene

1994 • 356 citations

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

1991 • 340 citations

Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin

1998 • 326 citations

Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System

1997 • 311 citations

Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast.

1996 • 293 citations

A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S-phase and mitosis in the absence of G1 cyclins.

1996 • 285 citations

Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2.

1992 • 281 citations

Identification of the yeast MCM3-related protein as a component of xenopus DNA replication licensing factor

1995 • 280 citations

MCM proteins: evolution, properties, and role in DNA replication

1998 • 275 citations

A quantitative model for the cdc2 control of S phase and mitosis in fission yeast

1996 • 267 citations

p65cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast

1995 • 259 citations

Interaction between the Origin Recognition Complex and the Replication Licensing Systemin Xenopus

1996 • 255 citations

Human CDC6/Cdc18 Associates with Orc1 and Cyclin-cdk and Is Selectively Eliminated from the Nucleus at the Onset of S Phase

1998 • 251 citations

Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase cdk

1998 • 235 citations

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication.

1995 • 234 citations

Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.

1993 • 233 citations

MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells

1995 • 220 citations

Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis.

1995 • 220 citations

A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts

1990 • 209 citations

Biochemical Analysis of the Intrinsic Mcm4-Mcm6-Mcm7 DNA Helicase Activity

1999 • 205 citations

DNA replication in eukaryotic cells

1997 • 194 citations

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

1994 • 173 citations

Regulation of the replication initiator protein p65^cdc18 by CDK phosphorylation

1997 • 165 citations

Biochemical Function of Mouse Minichromosome Maintenance 2 Protein

1998 • 139 citations

Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex.

1996 • 126 citations

The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts

1995 • 119 citations

Chromatin binding, nuclear localization and phosphorylation of Xenopus cdc21 are cell-cycle dependent and associated with the control of initiation of DNA replication.

1996 • 112 citations

A Human Homologue of the Yeast Replication Protein Cdc21. Interactions with Other Mcm Proteins

1995 • 87 citations

Chromotin binding, nuclear localization and phosphorylation of Xenopus cdc21 are cell-cycle dependent and associated with the control of initiation of DNA replication.

1996 • 86 citations

Cell Cycle-Dependent Regulation of Human DNA Polymerase α-Primase Activity by Phosphorylation

1999 • 85 citations

In Vivo Interaction of Human MCM Heterohexameric Complexes with Chromatin

1997 • 84 citations

Cell Cycle- and Chromatin Binding State-dependent Phosphorylation of Human MCM Heterohexameric Complexes

1998 • 84 citations

Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase α

1998 • 69 citations

A Human Homologue of the Yeast Replication Protein Cdc21

1995 • 63 citations

Cyclin-dependent kinase and initiation at eukaryotic origins: a replication switch?

1997 • 47 citations

Ectopic induction of Clb2 in early G ₁ phase is sufficient to block prereplicative complex formation in Saccharomyces cerevisiae

1998 • 43 citations

The DNA replication licensing system.

1997 • 20 citations