Chromatin binding, nuclear localization and phosphorylation of Xenopus cdc21 are cell-cycle dependent and associated with the control of initiation of DNA replication.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1992 • 1,279 citations

Chapter 30 Cell Cycle Extracts

1991 • 953 citations

Formation in Vitro of Sperm Pronuclei and Mitotic Chromosomes Induced by Amphibian Ooplasmic Components

1983 • 630 citations

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

1986 • 622 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

Two steps in the assembly of complexes at yeast replication origins in vivo

1994 • 566 citations

STRUCTURE AND FUNCTION OF SIMIAN VIRUS 40 LARGE TUMOR ANTIGEN

1992 • 506 citations

Identification and cloning of localized maternal RNAs from xenopus eggs

1985 • 464 citations

A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication

1993 • 400 citations

Protein-DNA interactions at a yeast replication origin

1992 • 380 citations

Purification of an MCM-containing complex as a component of the DNA replication licensing system

1995 • 361 citations

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

1991 • 340 citations

A group of interacting yeast DNA replication genes.

1991 • 325 citations

Cell cycle extracts.

1991 • 304 citations

Identification of the yeast MCM3-related protein as a component of xenopus DNA replication licensing factor

1995 • 280 citations

Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.

1993 • 233 citations

Subcellular localization of yeast CDC46 varies with the cell cycle.

1990 • 226 citations

Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor

1993 • 198 citations

Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function.

1991 • 196 citations

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro

1989 • 192 citations

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

1994 • 173 citations

DNA synthesis in a cell-free system from Xenopus eggs: Priming and elongation on single-stranded DNA in vitro

1982 • 147 citations

The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.

1990 • 138 citations

Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein

1992 • 137 citations

Distinct roles of cdk2 and cdc2 in RP-A phosphorylation during the cell cycle

1993 • 136 citations

Identification of nuclear pre-replication centers poised for DNA synthesis in Xenopus egg extracts: immunolocalization study of replication protein A.

1992 • 134 citations

Fission yeastcdc21⁺belongs to a family of proteins involved in an early step of chromosome replication

1992 • 131 citations

Study of the cell cycle-dependent assembly of the DNA pre-replication centres in Xenopus egg extracts.

1994 • 124 citations

Fission yeast cdc21, a member of the MCM protein family, is required for onset of S phase and is located in the nucleus throughout the cell cycle.

1996 • 98 citations

A general protocol for evaluating the specific effects of DNA replication inhibitors

1993 • 91 citations

A Human Homologue of the Yeast Replication Protein Cdc21. Interactions with Other Mcm Proteins

1995 • 87 citations

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mem replication proteins

1993 • 87 citations

Reversible effects of nuclear membrane permeabilization on DNA replication: evidence for a positive licensing factor

1993 • 83 citations

An analysis of the regulation of DNA synthesis by cdk2, Cip1, and licensing factor.

1995 • 79 citations

Determination of initiation of DNA replication before and after nuclear formation in Xenopus egg cell free extracts.

1993 • 78 citations

Expression, phosphorylation and nuclear localization of the human P1 protein, a homologue of the yeast Mcm 3 replication protein

1995 • 59 citations

Changes in the nuclear distribution of DNA polymerase alpha and PCNA/cyclin during the progress of the cell cycle, in a cell-free extract of Xenopus eggs

1989 • 51 citations

The Phenotype of the Minichromosome Maintenance Mutant mcm3 Is Characteristic of Mutants Defective in DNA Replication

1990 • 47 citations

A murine replication protein accumulates temporarily in the heterochromatic regions of nuclei prior to initiation of DNA replication

1995 • 36 citations