The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

Mammalian Cell Fusion : Studies on the Regulation of DNA Synthesis and Mitosis

1970 • 759 citations

Isolation of a protein that is essential for the first step of nuclear protein import

1994 • 710 citations

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

1986 • 622 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

MUTANTS OF S. CEREVISIAE DEFECTIVE IN THE MAINTENANCE OF MINICHROMOSOMES

1984 • 419 citations

A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication

1993 • 400 citations

Purification of an MCM-containing complex as a component of the DNA replication licensing system

1995 • 361 citations

Identification of the yeast MCM3-related protein as a component of xenopus DNA replication licensing factor

1995 • 280 citations

Steps in the assembly of replication-competent nuclei in a cell-free system from Xenopus eggs.

1988 • 236 citations

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication.

1995 • 234 citations

Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.

1993 • 233 citations

Subcellular localization of yeast CDC46 varies with the cell cycle.

1990 • 226 citations

MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells

1995 • 220 citations

International Cell Biology 1980–1981.

1982 • 204 citations

Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor

1993 • 198 citations

Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function.

1991 • 196 citations

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro

1989 • 192 citations

p34cdc2: the S and M kinase?

1990 • 192 citations

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

1994 • 173 citations

The nuclear membrane prevents replication of human G2 nuclei but not G1 nuclei in Xenopus egg extract

1992 • 140 citations

Cell cycle-regulated nuclear import and export of Cdc47, a protein essential for initiation of DNA replication in budding yeast.

1995 • 140 citations

The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.

1990 • 138 citations

Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein

1992 • 137 citations

Identification of nuclear pre-replication centers poised for DNA synthesis in Xenopus egg extracts: immunolocalization study of replication protein A.

1992 • 134 citations

Fission yeastcdc21⁺belongs to a family of proteins involved in an early step of chromosome replication

1992 • 131 citations

Interactions of human nuclear proteins P1Mcm3 and P1Cdc46.

1995 • 130 citations

Periodic DNA synthesis in cell-free extracts of Xenopus eggs.

1987 • 127 citations

The MCM2-3-5 proteins: are they replication licensing factors?

1994 • 124 citations

Study of the cell cycle-dependent assembly of the DNA pre-replication centres in Xenopus egg extracts.

1994 • 124 citations

A human nuclear protein with sequence homology to a family of early s phase proteins is required for entry into s phase and for cell division

1994 • 120 citations

c-Jun is phosphorylated by the DNA-dependent protein kinasein vitro; definition of the minimal kinase recognition motif

1993 • 104 citations

Interactions of Human Nuclear Proteins P1Mcm3 and P1Cdc46

1995 • 103 citations

CDC46/MCM5, a yeast protein whose subcellular localization is cell cycle-regulated, is involved in DNA replication at autonomously replicating sequences.

1992 • 99 citations

Heat shock-induced changes in the structural stability of proteinaceous karyoskeletal elements in vitro and morphological effects in situ.

1987 • 88 citations

The P1 family: a new class of nuclear mammalian proteins related to the yeast Mem replication proteins

1993 • 87 citations

A Human Homologue of the Yeast Replication Protein Cdc21. Interactions with Other Mcm Proteins

1995 • 87 citations

Reversible effects of nuclear membrane permeabilization on DNA replication: evidence for a positive licensing factor

1993 • 83 citations

The fission yeast cdc19+ gene encodes a member of the MCM family of replication proteins

1994 • 78 citations

Determination of initiation of DNA replication before and after nuclear formation in Xenopus egg cell free extracts.

1993 • 78 citations

DNA replication occurs at discrete sites in pseudonuclei assembled from purified DNA in vitro

1991 • 76 citations

A Human Homologue of the Yeast Replication Protein Cdc21

1995 • 63 citations

Extracts from eggs and oocytes of Xenopus Laevis differ in their capacities for nuclear assembly and dna replication

1990 • 28 citations

Identification of an amphibian oocyte nuclear protein as a candidate for a role in embryonic DNA replication.

1993 • 15 citations

Technical wonders of the past

1995 • 1 citations