S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

Genetic Control of the Cell Division Cycle in Yeast

1974 • 1,588 citations

[10] 5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1987 • 1,375 citations

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1992 • 1,279 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1994 • 902 citations

Cyclin-Dependent Regulation of G ₁ in Mammalian Fibroblasts

1993 • 767 citations

Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast

1981 • 740 citations

A p53-Dependent Mouse Spindle Checkpoint

1995 • 668 citations

A Yeast Chromosomal Origin of DNA Replication Defined by Multiple Functional Elements

1992 • 634 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

An essential G1 function for cyclin-like proteins in yeast

1989 • 574 citations

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor

1993 • 569 citations

Two steps in the assembly of complexes at yeast replication origins in vivo

1994 • 566 citations

The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog.

1988 • 563 citations

Genes involved in sister chromatid separation are needed for b-type cyclin proteolysis in budding yeast

1995 • 561 citations

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation

1994 • 543 citations

CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

1993 • 521 citations

Control of the yeast cell cycle by the Cdc28 protein kinase

1993 • 502 citations

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast.

1993 • 483 citations

Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle

1994 • 478 citations

The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae

1991 • 463 citations

The fission yeast cdc18+ gene product couples S phase to START and mitosis

1993 • 446 citations

DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae.

1988 • 445 citations

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a ‘reductional’ anaphase in the budding yeast Saccharomyces cerevisiae.

1995 • 402 citations

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

1994 • 393 citations

CLB5: a novel B cyclin from budding yeast with a role in S phase.

1992 • 391 citations

Protein-DNA interactions at a yeast replication origin

1992 • 380 citations

Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers

1990 • 376 citations

Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins

1993 • 376 citations

Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene

1994 • 356 citations

A potential positive feedback loop controlling CLN1 and CLN2 gene expression at the start of the yeast cell cycle

1991 • 341 citations

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

1991 • 340 citations

Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae.

1992 • 310 citations

A cyclin B homolog in S. cerevisiae: Chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis

1991 • 310 citations

Sequential function of gene products relative to DNA synthesis in the yeast cell cycle

1976 • 302 citations

A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein.

1989 • 296 citations

Cell cycle regulted transcription in yeast

1994 • 283 citations

Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2.

1992 • 281 citations

An Inhibitor of p34 ^CDC28 Protein Kinase Activity from Saccharomyces cerevisiae

1993 • 236 citations

Suppression of DNA replication via Mos function during meiotic divisions in Xenopus oocytes.

1994 • 227 citations

Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis.

1995 • 220 citations

A question of time: Replication origins of eukaryotic chromosomes

1992 • 153 citations

Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division.

1992 • 143 citations

NUCLEO‐CYTOPLASMIC INTERACTIONS IN THE ACHIEVEMENT OF NUCLEAR SYNCHRONY IN DNA SYNTHESIS AND MITOSIS IN MULTINUCLEATE CELLS

1971 • 133 citations

Disruption of regulatory gene GAL80 in Saccharomyces cerevisiae: effects on carbon-controlled regulation of the galactose/melibiose pathway genes.

1984 • 129 citations

Uncoupled cell cycle without mitosis induced by a protein kinase inhibitor, K-252a.

1991 • 121 citations

Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex.

1994 • 99 citations

A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle.

1993 • 95 citations

The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1

1992 • 90 citations

A general approach to the isolation of cell cycle-regulated genes in the budding yeast, Saccharomyces cerevisiae

1991 • 87 citations

Specialization of B-type cyclins for mitosis or meiosis in S. cerevisiae.

1995 • 84 citations

Initiation of chromosomal DNA replication in eukaryotes. Lessons from lambda.

1994 • 76 citations

The initiation of chromosomal DNA replication in eukaryotes

1990 • 65 citations

NCA3, a nuclear gene involved in the mitochondrial expression of subunits 6 and 8 of the Fo-F1 ATP synthase of S. cerevisiae

1995 • 62 citations

De novo synthesis of budding yeast DNA polymerase alpha and POL1 transcription at the G1/S boundary are not required for entrance into S phase.

1993 • 52 citations