Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

On the Regulation of DNA Replication in Bacteria

1963 • 1,441 citations

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1992 • 1,279 citations

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast.

1997 • 673 citations

A Yeast Chromosomal Origin of DNA Replication Defined by Multiple Functional Elements

1992 • 634 citations

Two steps in the assembly of complexes at yeast replication origins in vivo

1994 • 566 citations

Spreading of transcriptional represser SIR3 from telomeric heterochromatin

1996 • 523 citations

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

1997 • 496 citations

Repression and activation by multiprotein complexes that alter chromatin structure.

1996 • 444 citations

Yeast Origin Recognition Complex Functions in Transcription Silencing and DNA Replication

1993 • 435 citations

MUTANTS OF S. CEREVISIAE DEFECTIVE IN THE MAINTENANCE OF MINICHROMOSOMES

1984 • 419 citations

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a ‘reductional’ anaphase in the budding yeast Saccharomyces cerevisiae.

1995 • 402 citations

A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication

1993 • 400 citations

INITIATION OF DNA REPLICATION IN EUKARYOTIC CELLS

1997 • 399 citations

The Xenopus Cdc6 Protein Is Essential for the Initiation of a Single Round of DNA Replication in Cell-Free Extracts

1996 • 387 citations

Protein-DNA interactions at a yeast replication origin

1992 • 380 citations

COLD-SENSITIVE CELL-DIVISION-CYCLE MUTANTS OF YEAST: ISOLATION, PROPERTIES, AND PSEUDOREVERSION STUDIES

1982 • 372 citations

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state

1995 • 366 citations

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

1996 • 362 citations

ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome

1995 • 357 citations

A group of interacting yeast DNA replication genes.

1991 • 325 citations

Identification of the yeast MCM3-related protein as a component of xenopus DNA replication licensing factor

1995 • 280 citations

Interaction between the Origin Recognition Complex and the Replication Licensing Systemin Xenopus

1996 • 255 citations

The structure and function of yeast ARS elements

1993 • 244 citations

Coordinate Binding of ATP and Origin DNA Regulates the ATPase Activity of the Origin Recognition Complex

1997 • 243 citations

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication.

1995 • 234 citations

Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.

1993 • 233 citations

The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin

1996 • 213 citations

The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators.

1995 • 204 citations

Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function.

1991 • 196 citations

The origin recognition complex has essential functions in transcriptional silencing and chromosomal replication.

1995 • 187 citations

Initiation complex assembly at budding yeast replication origins begins with the recognition of a bipartite sequence by limiting amounts of the initiator, ORC.

1995 • 179 citations

The role of MCM/P1 proteins in the licensing of DNA replication.

1996 • 176 citations

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

1994 • 173 citations

CDC45, a Novel Yeast Gene That Functions with the Origin Recognition Complex and Mcm Proteins in Initiation of DNA Replication

1997 • 171 citations

ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae.

1996 • 166 citations

ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae.

1996 • 141 citations

The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.

1990 • 138 citations

Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein

1992 • 137 citations

3′ → 5′ Exonucleases of DNA Polymerases ϵ and δ Correct Base Analog Induced DNA Replication Errors on Opposite DNA Strands in Saccharomyces cerevisiae

1996 • 131 citations

The role of MCM/P1 proteins in the licensing of DNA replication

1996 • 131 citations

The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts

1995 • 119 citations

Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication.

1996 • 118 citations

DNA polymerase epsilon may be dispensable for SV40- but not cellular-DNA replication.

1996 • 116 citations

Analysis of a circular derivative of Saccharomyces cerevisiae chromosome III: a physical map and identification and location of ARS elements.

1991 • 111 citations

Yeast DNA polymerases and their role at the replication fork

1995 • 110 citations

Replicator dominance in a eukaryotic chromosome.

1994 • 94 citations

XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication.

1996 • 84 citations

Localization of a DNA Replication Origin and Termination Zone on Chromosome III of Saccharomyces cerevisiae

1992 • 79 citations

Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication

1996 • 56 citations

Eukaryotic replicators and associated protein complexes

1995 • 46 citations

Localization of a DNA replication origin and termination zone on chromosome III of Saccharomyces cerevisiae.

1992 • 42 citations

DNA replication, second edition

1992 • 24 citations