Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast.

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1992 • 1,279 citations

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1994 • 902 citations

Two steps in the assembly of complexes at yeast replication origins in vivo

1994 • 566 citations

Genes involved in sister chromatid separation are needed for b-type cyclin proteolysis in budding yeast

1995 • 561 citations

CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

1993 • 521 citations

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast.

1993 • 483 citations

Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle

1994 • 478 citations

The cell cycle: an introduction

1994 • 466 citations

The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae

1991 • 463 citations

The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation.

1992 • 414 citations

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a ‘reductional’ anaphase in the budding yeast Saccharomyces cerevisiae.

1995 • 402 citations

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

1994 • 393 citations

CLB5: a novel B cyclin from budding yeast with a role in S phase.

1992 • 391 citations

Protein-DNA interactions at a yeast replication origin

1992 • 380 citations

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state

1995 • 366 citations

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

1996 • 362 citations

ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome

1995 • 357 citations

Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene

1994 • 356 citations

A potential positive feedback loop controlling CLN1 and CLN2 gene expression at the start of the yeast cell cycle

1991 • 341 citations

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

1991 • 340 citations

Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae.

1995 • 337 citations

Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae.

1992 • 310 citations

Sequential function of gene products relative to DNA synthesis in the yeast cell cycle

1976 • 302 citations

The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.

1994 • 299 citations

Mother Cell–Specific HO Expression in Budding Yeast Depends on the Unconventional Myosin Myo4p and Other Cytoplasmic Proteins

1996 • 299 citations

Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae

1992 • 296 citations

Cell cycle regulted transcription in yeast

1994 • 283 citations

p65cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast

1995 • 259 citations

Cell Cycle Regulation of the Yeast Cdc7 Protein Kinase by Association With the Dbf4 Protein†

1993 • 250 citations

An Inhibitor of p34 ^CDC28 Protein Kinase Activity from Saccharomyces cerevisiae

1993 • 236 citations

Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.

1993 • 233 citations

Yeast origin recognition complex is involved in DNA replication and transcriptional silencing

1993 • 231 citations

Subcellular localization of yeast CDC46 varies with the cell cycle.

1990 • 226 citations

The identification of a second cell cycle control on the HO promoter in yeast: Cell cycle regulation of SWI5 nuclear entry

1990 • 215 citations

The origin recognition complex has essential functions in transcriptional silencing and chromosomal replication.

1995 • 187 citations

Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae.

1992 • 145 citations

Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division.

1992 • 143 citations

Cell cycle-regulated nuclear import and export of Cdc47, a protein essential for initiation of DNA replication in budding yeast.

1995 • 140 citations

Mcm1 Is Required To Coordinate G₂-Specific Transcription in Saccharomyces cerevisiae

1995 • 131 citations

cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.

1996 • 129 citations

The Saccharomyces cerevisiae CDC6 gene is transcribed at late mitosis and encodes a ATP/GTPase controlling S phase initiation.

1994 • 96 citations

A general approach to the isolation of cell cycle-regulated genes in the budding yeast, Saccharomyces cerevisiae

1991 • 87 citations

Regulation of Saccharomyces cerevisiae CDC7 function during the cell cycle.

1993 • 73 citations

The CDC4 gene product is associated with the yeast nuclear skeleton

1990 • 30 citations