myc Family Oncogenes in the Development of Normal and Neoplastic Cells

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage

1984 • 2,248 citations

Association of Multiple Copies of the N-mycOncogene with Rapid Progression of Neuroblastomas

1985 • 1,989 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1985 • 1,782 citations

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

1982 • 1,746 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

1982 • 1,424 citations

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

1983 • 1,407 citations

Hemoglobin Synthesis in Murine Virus-Induced Leukemic Cells In Vitro: Stimulation of Erythroid Differentiation by Dimethyl Sulfoxide

1971 • 1,371 citations

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

GERM-LINE TRANSFORMATION OF MICE

1986 • 1,165 citations

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1988 • 1,160 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

A thousand and one protein kinases

1987 • 1,066 citations

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

1978 • 972 citations

Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection

1990 • 957 citations

Amplification and expression of the c-myc oncogene in human lung cancer cell lines

1983 • 921 citations

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1984 • 906 citations

Sequence-Specific DNA Binding by the c-Myc Protein

1990 • 893 citations

A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.

1989 • 863 citations

MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer

1989 • 861 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

TRANSCRIPTION TERMINATION AND THE REGULATION OF GENE EXPRESSION

1986 • 811 citations

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo

1987 • 796 citations

Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.

1983 • 764 citations

Regulation of terminal differentiation of cultured human keratinocytes by vitamin A

1981 • 756 citations

Translocations Among Antibody Genes in Human Cancer

1983 • 736 citations

Ordered rearrangement of immunoglobulin heavy chain variable region segments.

1984 • 736 citations

The human c-myc oncogene: Structural consequences of translocation into the igh locus in Burkitt lymphoma

1983 • 732 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

Transposition and amplification of oncogene-related sequences in human neuroblastomas

1983 • 711 citations

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1987 • 696 citations

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

1985 • 652 citations

Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma

1985 • 644 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line

1982 • 630 citations

Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas

1982 • 624 citations

Parallel Association of Fos and Jun Leucine Zippers Juxtaposes DNA Binding Domains

1989 • 607 citations

The MYC protein activates transcription of the alpha-prothymosin gene.

1991 • 589 citations

Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia

1984 • 567 citations

Differential expression of myc family genes during murine development

1986 • 542 citations

Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment

1986 • 536 citations

Extreme instability of myc mRNA in normal and transformed human cells.

1984 • 522 citations

Translocation and Rearrangements of the c- myc Oncogene Locus in Human Undifferentiated B-Cell Lymphomas

1983 • 514 citations

Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro.

1988 • 511 citations

fos-associated cellular p39 is related to nuclear transcription factor AP-1

1988 • 508 citations

Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas

1983 • 504 citations

Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells.

1984 • 502 citations

The achaete-scute gene complex of D. melanogaster: Conserved Domains in a subset of genes required for neurogenesis and their homology to myc

1987 • 501 citations

Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite

1983 • 500 citations

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

1990 • 484 citations

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

1988 • 481 citations

An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation.

1988 • 476 citations

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

1989 • 475 citations

Transgenic Animals

1988 • 473 citations

Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos.

1988 • 471 citations

Preferential Heterodimer Formation by Isolated Leucine Zippers from Fos and Jun

1989 • 469 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

1988 • 455 citations

Expression and amplification of the N-myc gene in primary retinoblastoma

1984 • 451 citations

daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex

1988 • 442 citations

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

1986 • 441 citations

Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.

1983 • 436 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma.

1984 • 400 citations

Alterations of myc , myb , and ras ^Ha Proto-Oncogenes In Cancers Are Frequent and Show Clinical Correlation

1986 • 379 citations

Expression of c-myc changes during differentiation of mouse erythroleukaemia cells

1984 • 376 citations

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice.

1989 • 365 citations

Teratocarcinomas as a model system for the study of embryogenesis and neoplasia

1975 • 361 citations

lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif

1989 • 358 citations

Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion

1984 • 358 citations

Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins

1989 • 358 citations

Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

1990 • 355 citations

Nuclear location signals in polyoma virus large-T

1986 • 351 citations

Activation and somatic mutation of the translocated c-myc gene in Burkitt lymphoma cells

1984 • 335 citations

Two human c-onc genes are located on the long arm of chromosome 8.

1982 • 329 citations

Intragenic pausing and anti-sense transcription within the murine c-myc locus.

1986 • 326 citations

Molecular Basis of Human B Cell Neoplasia

1985 • 316 citations

Expression of a transfected human c-myconcogene inhibits differentiation of a mouse erythroleukaemia cell line

1986 • 309 citations

Retinoic Acid-Induced Neural Differentiation of Embryonal Carcinoma Cells

1983 • 308 citations

Introduction of a μ immunoglobulin gene into the mouse germ line: Specific expression in lymphoid cells and synthesis of functional antibody

1984 • 304 citations

Rapid Cytoplasmic Turnover of c-myc mRNA: Requirement of the 3′ Untranslated Sequences

1987 • 302 citations

c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors

1985 • 300 citations

Identification of the Human c-myc Protein Nuclear Translocation Signal

1988 • 299 citations

Nuclear localization and DNA binding of the transforming gene product of avian myelocytomatosis virus

1982 • 298 citations

Proteins encoded by v-myc and c-myc oncogenes: Identification and localization in acute leukemia virus transformants and bursal lymphoma cell lines

1983 • 297 citations

N-myc amplification causes down-modulation of MHC class I antigen expression in neuroblastoma

1986 • 297 citations

Human small-cell lung cancers show amplification and expression of the N-myc gene.

1986 • 293 citations

Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture

1985 • 288 citations

Myc oncoproteins are phosphorylated by casein kinase II.

1989 • 287 citations

The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation

1989 • 286 citations

Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding

1989 • 281 citations

Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus

1984 • 274 citations

Post-transcriptional control of myc and p53 expression during differentiation of the embryonal carcinoma cell line F9

1985 • 274 citations

DNA and RNA from Uninfected Vertebrate Cells Contain Nucleotide Sequences Related to the Putative Transforming Gene of Avian Myelocytomatosis Virus

1979 • 273 citations

Human N-myc is closely related in organization and nucleotide sequence to c-myc

1986 • 273 citations

The achaete-scute gene complex of Drosophila melanogaster comprises four homologous genes.

1988 • 271 citations

Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice

1987 • 271 citations

Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma

1984 • 259 citations

Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression

1986 • 254 citations

Negative autoregulation of c-myc transcription.

1990 • 247 citations

Activated Expression of the N- myc Gene in Human Neuroblastomas and Related Tumors

1984 • 246 citations

Sequence requirements for premature termination of transcription in the human c-myc gene

1988 • 246 citations

Nuclear location of the putative transforming protein of avian myelocytomatosis virus

1982 • 245 citations

Molecular basis of human B cell neoplasia

1985 • 244 citations

myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course.

1987 • 242 citations

Identification of nuclear proteins encoded by viral and cellular myc oncogenes

1983 • 235 citations

Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation.

1984 • 234 citations

Mutations in the First Exon Are Associated with Altered Transcription of c- myc in Burkitt Lymphoma

1987 • 228 citations

Posttranscriptional mechanisms are responsible for accumulation of truncated c-myc RNAs in murine plasma cell tumors

1985 • 227 citations

Transcription elongation and eukaryotic gene regulation.

1990 • 227 citations

Retinoic acid-induced neural differentiation of embryonal carcinoma cells.

1983 • 213 citations

Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals

1984 • 212 citations

Identification of the human c-myc protein nuclear translocation signal.

1988 • 207 citations

Oncogenesis of the Lens in Transgenic Mice

1987 • 202 citations

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein

1989 • 198 citations

Mouse c-myc Oncogene Is Located on Chromosome 15 and Translocated to Chromosome 12 in Plasmacytomas

1982 • 197 citations

c-myc antisense transcripts accelerate differentiation and inhibit G1 progression in murine erythroleukemia cells.

1988 • 195 citations

N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization.

1988 • 194 citations

The protein encoded by the human proto-oncogene c-myc.

1984 • 192 citations

Nucleotide sequence of the human N-myc gene.

1986 • 190 citations

The Regulation and Expression of c-myc in Normal and Malignant Cells

1986 • 185 citations

N-myc can cooperate with ras to transform normal cells in culture.

1985 • 184 citations

Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences.

1987 • 182 citations

Induced muscle differentiation in an embryonal carcinoma cell line.

1983 • 181 citations

The protein products of the myc and myb oncogenes and adenovirus E1a are structurally related

1983 • 178 citations

Oncogenes and the molecular origins of cancer

1990 • 177 citations

Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes

1985 • 176 citations

Novel promoter upstream of the human c-myc gene and regulation of c-myc expression in B-cell lymphomas.

1986 • 176 citations

Expression of N-myc in teratocarcinoma stem cells and mouse embryos

1985 • 173 citations

Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo.

1989 • 172 citations

Regulation of c-myc mRNA Stability In Vitro by a Labile Destabilizer with an Essential Nucleic Acid Component

1989 • 172 citations

Truncation of exon 1 from the c-myc gene results in prolonged c-myc mRNa stability.

1985 • 172 citations

Expression of the immunoglobulin C mu gene in mouse T and B lymphoid and myeloid cell lines.

1980 • 170 citations

Enhanced expression of the N-myc gene in Wilms' tumors.

1986 • 170 citations

Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins.

1989 • 164 citations

Transcriptional and posttranscriptional control of c-myc during myogenesis: its mRNA remains inducible in differentiated cells and does not suppress the differentiated phenotype.

1986 • 157 citations

Nucleotide sequence comparison of normal and translocated murine c-myc genes

1984 • 154 citations

Transcriptional control of the endogenous MYC protooncogene by antisense RNA.

1987 • 153 citations

Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line

1983 • 152 citations

c-myc regulation during retinoic acid-induced differentiation of F9 cells is posttranscriptional and associated with growth arrest.

1986 • 147 citations

Two functionally different regions in Fos are required for the sequence-specific DNA interaction of the Fos/Jun protein complex

1989 • 147 citations

Structure and expression of the murine N-myc gene.

1986 • 146 citations

A negative transcriptional control element located upstream of the murine c-myc gene.

1986 • 142 citations

c-myc and c-fos expression in differentiating mouse primary keratinocytes.

1986 • 130 citations

The human myc gene family: structure and activity of L-myc and an L-myc pseudogene.

1987 • 130 citations

A transcriptional repressor of c-myc

1989 • 129 citations

Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic mice.

1987 • 129 citations

Dynamic Expression Pattern of the myc Protooncogene in Midgestation Mouse Embryos

1989 • 129 citations

Transcription attenuation.

1988 • 128 citations

Identification and Characterization of the Protein Encoded by the Human N- myc Oncogene

1986 • 128 citations

Multiple mechanisms for transcriptional regulation of the myc gene family in small-cell lung cancer.

1988 • 127 citations

Neoplastic transformation by the human gene N-myc.

1987 • 124 citations

A novel alteration in the structure of an activated c-myc gene in a variant t(2;8) burkitt lymphoma

1984 • 122 citations

Activation of a translocated c-myc gene: role of structural alterations in the upstream region.

1984 • 122 citations

Transcriptional regulation of c-myc during chemically induced differentiation of HL-60 cultures.

1985 • 120 citations

Human proto-oncogene N-myc encodes nuclear proteins that bind DNA.

1986 • 120 citations

Transgenic mice bearing the human c-myc gene activated by an immunoglobulin enhancer: a pre-B-cell lymphoma model.

1988 • 118 citations

The Human myc Gene Family

1986 • 116 citations

Transcriptional activation of the translocated c-myc oncogene in mouse plasmacytomas: Similar RNA levels in tumor and proliferating normal cells

1984 • 116 citations

Identification of reciprocal translocation sites within the c-myc oncogene and immunoglobulin μ locus in a Burkitt lymphoma

1983 • 113 citations

N-myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross-regulation with c-myc.

1989 • 112 citations

Cell-type-specific pattern of myc protooncogene expression in developing human embryos.

1985 • 111 citations

N-myc is frequently activated by proviral insertion in MuLV-induced T cell lymphomas.

1989 • 109 citations

Two distinct mechanisms of transcriptional control operate on c-myc during differentiation of HL60 cells.

1988 • 106 citations

A FOS protein is present in a complex that binds a negative regulator of MYC.

1989 • 106 citations

Expression of human alpha 1-acid glycoprotein genes in cultured cells and in transgenic mice.

1988 • 105 citations

Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.

1988 • 102 citations

fos/jun and Octamer-binding Protein Interact with a Common Site in a Negative Element of the Human c-myc Gene

1989 • 102 citations

Identification and characterization of the NMYC gene product in human neuroblastoma cells by monoclonal antibodies with defined specificities.

1986 • 102 citations

A Point Mutation in the c- myc Locus of a Burkitt Lymphoma Abolishes Binding of a Nuclear Protein

1988 • 102 citations

The c-myc gene encodes superimposed RNA polymerase II and III promoters

1987 • 99 citations

IgH enhancer-mediated deregulation of N-myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c-myc expression.

1989 • 97 citations

The vertebrate homolog of the putative transforming gene of avian myelocytomatosis virus: Characteristics of the DNA locus and its RNA transcript

1980 • 97 citations

Transcriptional and post-transcriptional regulation of c-mye expression during the differentiation of murine erythroleukemia Friend cells

1986 • 97 citations

The first exon of the c-myc proto-oncogene contains a novel positive control element.

1986 • 96 citations

The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles.

1990 • 96 citations

Trans-acting elements modulate expression of the human c-myc gene in Burkitt lymphoma cells.

1986 • 95 citations

L-myc cooperates with ras to transform primary rat embryo fibroblasts.

1988 • 93 citations

Antisense Myc sequences induce differentiation of F9 cells.

1988 • 90 citations

Transcripts of the immunoglobulin C mu gene vary in structure and splicing during lymphoid development.

1980 • 89 citations

Rat c-myc oncogene is located on chromosome 7 and rearranges in immunocytomas with t(6:7) chromosomal translocation

1983 • 88 citations

DNA sequences that mediate attenuation of transcription from the mouse protooncogene myc.

1989 • 87 citations

Structure and expression of the murine L-myc gene.

1987 • 85 citations

Intrinsic sites of transcription termination and pausing in the c-myc gene.

1988 • 85 citations

An E mu-v-abl transgene elicits plasmacytomas in concert with an activated myc gene.

1990 • 84 citations

Transcriptional and posttranscriptional control of c-myc gene expression in WEHI 231 cells.

1986 • 84 citations

Expression of the c-myc Proto-Oncogene during Development of Xenopus laevis

1986 • 83 citations

Regulation of c-myc mRNA stability in vitro by a labile destabilizer with an essential nucleic acid component.

1989 • 82 citations

Cellular myc (c-myc) in fish (rainbow trout): its relationship to other vertebrate myc genes and to the transforming genes of the MC29 family of viruses.

1986 • 79 citations

Regulation of expression of the c‐Myc proto‐oncogene

1987 • 78 citations

Molecular requirements for transcriptional initiation of the murine c-myc gene.

1989 • 77 citations

The Role of Chromosomal Translocations in B- and T-Cell Neoplasia

1987 • 76 citations

A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice

1988 • 75 citations

Expression of N-myc and c-src during the development of fetal human brain.

1987 • 71 citations

A cis-acting element in the promoter region of the murine c-myc gene is necessary for transcriptional block.

1989 • 70 citations

High-frequency disruption of the N-myc gene in embryonic stem and pre-B cell lines by homologous recombination.

1990 • 70 citations

Reciprocal chromosome translocation between c-myc and immunoglobulin γ2b genes

1983 • 69 citations

Expression of the c-myc oncogene under control of an immunoglobulin enhancer in E mu-myc transgenic mice.

1987 • 69 citations

Amplification and enhanced expression of the c-myc oncogene in mouse SEWA tumour cells

1985 • 69 citations

Alternative modes of c-myc regulation in growth factor-stimulated and differentiating cells.

1987 • 65 citations

Isolation and characterization of s-myc, a member of the rat myc gene family.

1989 • 64 citations

Structure and expression of B-myc, a new member of the myc gene family.

1988 • 63 citations

Expression of the c-myc proto-oncogene during development of Xenopus laevis.

1986 • 63 citations

The expression of multiple proto-oncogenes is differentially regulated during retinoic acid induced maturation of human neuroblastoma cell lines.

1988 • 58 citations

Negative regulation of c-myc transcription involves myc family proteins.

1988 • 55 citations

Oncogene cooperation in lymphocyte transformation: malignant conversion of E mu-myc transgenic pre-B cells in vitro is enhanced by v-H-ras or v-raf but not v-abl.

1989 • 55 citations

Chromatin structure of the murine c-myc locus: implications for the regulation of normal and chromosomally translocated genes.

1985 • 52 citations

Isolation and biochemical characterization of partially transformation-defective mutants of avian myelocytomatosis virus strain MC29: localization of the mutation to the myc domain of the 110,000-dalton gag-myc polyprotein

1982 • 52 citations

Molecular Foundations of Oncology

1992 • 52 citations

Site-directed mutagenesis of the gag-myc gene of avian myelocytomatosis virus 29: biological activity and intracellular localization of structurally altered proteins

1986 • 51 citations

Expression of normal and translocated c-myc alleles in Burkitt's lymphoma cells: evidence for different regulation.

1989 • 47 citations

Differential regulation of the N-myc gene in transfected cells and transgenic mice.

1990 • 46 citations

Strain dependency of B and T lymphoma development in immunoglobulin heavy chain enhancer (E mu)-myc transgenic mice.

1989 • 46 citations

A plasmacytoma-specific factor binds the c-myc promoter region.

1987 • 45 citations

IgH enhancer deregulated expression of L-myc: abnormal T lymphocyte development and T cell lymphomagenesis.

1990 • 41 citations

Acceleration of B-lymphoid tumorigenesis in E mu-myc transgenic mice by v-H-ras and v-raf but not v-abl.

1989 • 40 citations

Molecular basis of heavy-chain class switching and switch region deletion in an Abelson virus-transformed cell line.

1984 • 39 citations

Transcription of c-myc in human mononuclear cells is regulated by an elongation block.

1987 • 38 citations

Sequence determinants of c-myc mRNA turn-over: influence of 3' and 5' non-coding regions.

1988 • 37 citations

The human L-myc gene is expressed as two forms of protein in small cell lung carcinoma cell lines: detection by monoclonal antibodies specific to two myc homology box sequences.

1989 • 37 citations

The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs.

1988 • 36 citations

Transgenic Mouse Models for Hematopoietic Tumorigenesis

1988 • 34 citations

Alternative processing of RNA transcribed from NMYC.

1987 • 33 citations

Organization and expression of the chicken N-myc gene.

1990 • 32 citations

Two N-myc polypeptides with distinct amino termini encoded by the second and third exons of the gene.

1989 • 30 citations

Multiple growth-associated nuclear proteins immunoprecipitated by antisera raised against human c-myc peptide antigens.

1986 • 27 citations

Translocation and rearrangement of c-myc into immunoglobulin alpha heavy chain locus in primary cells from acute lymphocytic leukemia.

1984 • 24 citations

Similarities and differences in the regulation of N-myc and c-myc genes in murine embryonal carcinoma cells

1987 • 23 citations

Inactivation of the N-myc gene product by single amino acid substitution of leucine residues located in the leucine-zipper region.

1989 • 21 citations

Normal Expression of a Rearranged and Mutated c- myc Oncogene After Transfection into Fibroblasts

1989 • 20 citations

Tumorigenicity of SEWA murine cells correlates with degree of c-myc amplification.

1988 • 20 citations

Mechanism of endogenous myc gene down-regulation in E mu-N-myc tumors.

1991 • 20 citations

Germ line c-myc is not down-regulated by loss or exclusion of activating factors in myc-induced macrophage tumors.

1989 • 16 citations

An Active Chromatin Structure Acquired by Translocated c-myc Genes

1986 • 15 citations

Expression of the L-myc gene is under positive control by short-lived proteins.

1987 • 13 citations

Characterization and Nuclear Localization of the v- and c-myc Proteins

1986 • 9 citations

An active chromatin structure acquired by translocated c-myc genes.

1986 • 7 citations

Products & Materials

1988 • 1 citations