lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1986 • 1,232 citations

Recognition of protein coding regions in DNA sequences

1982 • 927 citations

MyoD1: A Nuclear Phosphoprotein Requiring a Myc Homology Region to Convert Fibroblasts to Myoblasts

1988 • 839 citations

The human c-myc oncogene: Structural consequences of translocation into the igh locus in Burkitt lymphoma

1983 • 732 citations

Inhibition of restriction endonuclease Nel I cleavage by phosphorothioate groups and its application to oligonucleotide-directed mutagenesis

1986 • 560 citations

The achaete-scute gene complex of D. melanogaster: Conserved Domains in a subset of genes required for neurogenesis and their homology to myc

1987 • 501 citations

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

1988 • 481 citations

Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos.

1988 • 471 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex

1988 • 442 citations

The codon preference plot: graphic analysis of protein coding sequences and prediction of gene expression

1984 • 381 citations

New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia

1984 • 365 citations

Gene for α-Chain of Human T-Cell Receptor: Location on Chromosome 14 Region Involved in T-Cell Neoplasms

1985 • 300 citations

The achaete-scute gene complex of Drosophila melanogaster comprises four homologous genes.

1988 • 271 citations

The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15.

1988 • 236 citations

[66] Mapping of gene transcripts by nuclease protection assays and cDNA primer extension

1987 • 228 citations

A Common Mechanism of Chromosomal Translocation in T- and B-Cell Neoplasia

1986 • 205 citations

Nucleotide sequence of the human N-myc gene.

1986 • 190 citations

Biology of the human malignant lymphomas. IV. Functional characterization of ten diffuse histiocytic lymphoma cell lines

1978 • 179 citations

Common Region on Chromosome 14 in T-Cell Leukemia and Lymphoma

1984 • 174 citations

Locus of the α-Chain of the T-Cell Receptor Is Split by Chromosome Translocation in T-Cell Leukemias

1985 • 140 citations

Analysis of DNA surrounding the breakpoints of chromosomal translocations involving the β T cell receptor gene in human lymphoblastic neoplasms

1987 • 136 citations

Cytogenetic studies on patients with chronic T cell leukemia/lymphoma

1984 • 134 citations

A cluster of chromosome 11p13 translocations found via distinct D-D and D-D-J rearrangements of the human T cell receptor delta chain gene.

1988 • 127 citations

Location of Gene for β Subunit of Human T-Cell Receptor at Band 7q35, a Region Prone to Rearrangements in T Cells

1985 • 121 citations

The Human myc Gene Family

1986 • 116 citations

Structure and expression of the murine L-myc gene.

1987 • 85 citations

Long-term growth of malignant thymocytes in vitro

1989 • 80 citations

Chromosomal translocation involving the beta T cell receptor gene in acute leukemia.

1988 • 66 citations

Clinical and biologic characterization of T-cell neoplasias with rearrangements of chromosome 7 band q34

1988 • 62 citations

7q32-q36 translocations in childhood T cell leukemia: cytogenetic evidence for involvement of the T cell receptor beta-chain gene

1987 • 53 citations

Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia.

1987 • 50 citations