The achaete-scute gene complex of D. melanogaster: Conserved Domains in a subset of genes required for neurogenesis and their homology to myc

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Atlas of protein sequence and structure

1965 • 4,462 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Positional information and the spatial pattern of cellular differentiation

1969 • 2,957 citations

Genetic variations of Drosophila melanogaster

1967 • 2,612 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Ribonucleic acid isolated by cesium chloride centrifugation

1974 • 2,263 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning

1977 • 951 citations

An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences

1982 • 801 citations

Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing

1982 • 744 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide

1977 • 713 citations

A mew computer method for the storage and manipulation of DNA gel reading data

1980 • 679 citations

Developmental systems : insects

1972 • 666 citations

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3′ termini

1985 • 652 citations

Atlas of Protein Sequence and Structure 1969

1970 • 623 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

Graphic methods to determine the function of nucleic acid sequences

1984 • 367 citations

Microinjected c- myc as a Competence Factor

1985 • 361 citations

Nucleotide sequence of cloned cDNA of human c-myc oncogene

1983 • 316 citations

Molecular genetics of the achaete-scute gene complex of D. melanogaster

1985 • 287 citations

Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29

1983 • 287 citations

Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma

1983 • 286 citations

Human N-myc is closely related in organization and nucleotide sequence to c-myc

1986 • 273 citations

The expression of three members of the achaete-scute gene complex correlates with neuroblast segregation in Drosophila

1987 • 272 citations

Improvements of DNA sequencing gels

1981 • 269 citations

GENETIC ANALYSIS OF THE ACHAETE-SCUTE SYSTEM OF DROSOPHILA MELANOGASTER

1979 • 247 citations

Development and Determination of Hairs and Bristles in the Milkweed Bug, Oncopeltus Fasciatus (Lygaeidae, Hemiptera)

1966 • 243 citations

A systematic DNA sequencing strategy

1982 • 213 citations

The North American species of Drosophila

1921 • 195 citations

The protein encoded by the human proto-oncogene c-myc.

1984 • 192 citations

Nucleotide sequence of the human N-myc gene.

1986 • 190 citations

Nucleotide sequence analysis of the chicken c-myc gene reveals homologous and unique coding regions by comparison with the transforming gene of avian myelocytomatosis virus MC29, delta gag-myc.

1983 • 187 citations

Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29.

1983 • 184 citations

DEVELOPMENTAL ANALYSIS OF THE ACHAETE-SCUTE SYSTEM OF DROSOPHILA MELANOGASTER

1978 • 173 citations

Genetic Mosaics and Other Essays

1968 • 165 citations

Two or three bristles.

1955 • 152 citations

The development of the bristles in normal and some mutant types ofDrosophila melanogaster

1942 • 150 citations

Development of Sensory Systems in Arthropods

1978 • 148 citations

Structure and expression of the murine N-myc gene.

1986 • 146 citations

Independent subpatterns of sense organs require independent genes of the achaete-scute complex in Drosophila larvae

1987 • 144 citations

Excess function Hairy-wing mutations caused by gypsy and copia insertions within structural genes of the achaete-scute locus of Drosophila

1986 • 139 citations

Nucleotide sequence analysis of human c-myc locus, chicken homologue, and myelocytomatosis virus MC29 transforming gene reveals a highly conserved gene product.

1983 • 127 citations

Nucleotide sequence analysis of the proviral genome of avian myelocytomatosis virus (MC29).

1983 • 118 citations

Eucaryotic transposable genetic elements with inverted terminal repeats

1980 • 117 citations

A region of the Drosophila genome necessary for CNS development

1979 • 111 citations

Cellular controls in differentiation

1981 • 102 citations

Proto-oncogene c-myc is expressed in cerebellar neurons at different developmental stages.

1986 • 96 citations

Genetic Analysis of Cell Heredity in Imaginal Discs of Drosophila melanogaster

1971 • 95 citations

Molecular analysis of the yellow locus of Drosophila

1986 • 80 citations

The interaction of genetic and environmental factors in development

1926 • 73 citations

Defective neural development inDrosophila melanogaster embryos deficient for the tip of the X chromosome

1980 • 65 citations

Genetic analysis ofHairy-wing mutations

1986 • 61 citations

The Control of Growth and Form: a Study of the Epidermal Cell in an Insect

1960 • 54 citations

On the relation between chromosome changes and gene mutations.

1956 • 51 citations

The Control of Growth and Form: A Study of the Epidermal Cell of an Insect

1960 • 39 citations