A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

ras GENES

1987 • 3,818 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1977 • 2,070 citations

Cellular differentiation, cytidine analogs and DNA methylation

1980 • 1,803 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidine

1979 • 1,101 citations

Potential Metal-Binding Domains in Nucleic Acid Binding Proteins

1986 • 1,096 citations

Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro.

1982 • 932 citations

Cytoplasmic activation of human nuclear genes in stable heterocaryons

1983 • 839 citations

Plasticity of the Differentiated State

1985 • 839 citations

MyoD1: A Nuclear Phosphoprotein Requiring a Myc Homology Region to Convert Fibroblasts to Myoblasts

1988 • 839 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment

1986 • 536 citations

Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo

1984 • 520 citations

The achaete-scute gene complex of D. melanogaster: Conserved Domains in a subset of genes required for neurogenesis and their homology to myc

1987 • 501 citations

Growth factor control of skeletal muscle differentiation: commitment to terminal differentiation occurs in G1 phase and is repressed by fibroblast growth factor.

1987 • 480 citations

Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos.

1988 • 471 citations

daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex

1988 • 442 citations

Regulation of myogenic differentiation by type beta transforming growth factor.

1986 • 408 citations

Transfection of a DNA locus that mediates the conversion of 10T12 fibroblasts to myoblasts

1986 • 376 citations

Characterization of two putative smooth muscle cell lines from rat thoracic aorta

1976 • 375 citations

CHARACTERIZATION OF A UNIQUE MUSCLE CELL LINE

1974 • 343 citations

Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment

1977 • 335 citations

5-azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: Evidence for regulatory genes controlling determination

1984 • 330 citations

Deregulated expression of c-myc by murine erythroleukaemia cells prevents differentiation

1986 • 321 citations

Expression of a transfected human c-myconcogene inhibits differentiation of a mouse erythroleukaemia cell line

1986 • 309 citations

Diffusion-mediated control of myoblast fusion

1971 • 283 citations

Myogenic differentiation in permanent clonal mouse myoblast cell lines: Regulation by macromolecular growth factors in the culture medium

1981 • 259 citations

Myogenic lineage determination and differentiation: Evidence for a regulatory gene pathway

1988 • 253 citations

Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene.

1988 • 248 citations

Transforming growth factor-beta. A very potent inhibitor of myoblast differentiation, identical to the differentiation inhibitor secreted by Buffalo rat liver cells.

1986 • 247 citations

The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer.

1988 • 236 citations

The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation.

1987 • 221 citations

Serum and fibroblast growth factor inhibit myogenic differentiation through a mechanism dependent on protein synthesis and independent of cell proliferation.

1986 • 196 citations

Control by fibroblast growth factor of differentiation in the BC3H1 muscle cell line.

1985 • 166 citations

Molecular characterization of daughterless, a Drosophila sex determination gene with multiple roles in development.

1988 • 164 citations

Transcriptional and posttranscriptional control of c-myc during myogenesis: its mRNA remains inducible in differentiated cells and does not suppress the differentiated phenotype.

1986 • 157 citations

Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides

1978 • 150 citations

Distinctive effects of the viral oncogenes myc, erb, fps, and src on the differentiation program of quail myogenic cells.

1985 • 141 citations

Changes in phenotypic expression in embryonic and adult cells treated with 5-azacytidine

1982 • 137 citations

Mitogens and Oncogenes Can Block the Induction of Specific Voltage-Gated Ion Channels

1987 • 114 citations

Cloning and characterization of cDNA sequences corresponding to myosin light chains 1, 2, and 3, troponin-C, troponin-T, alpha-tropomyosin, and alpha-actin.

1982 • 107 citations

Regulation of creatine phosphokinase expression during differentiation of BC3H1 cells.

1983 • 105 citations

Regulation of surface expression of acetylcholine receptors in response to serum and cell growth in the BC3H1 muscle cell line.

1983 • 92 citations

Autonomous expression of c-myc in BC3H1 cells partially inhibits but does not prevent myogenic differentiation.

1987 • 86 citations

Differentiation, not determination, regulates muscle gene activation: transfection of troponin I genes into multipotential and muscle lineages of 10T1/2 cells.

1985 • 77 citations

Induction of vascular smooth muscle alpha-isoactin expression in BC3H1 cells.

1984 • 76 citations

Dexamethasone-dependent inhibition of differentiation of C2 myoblasts bearing steroid-inducible N-ras oncogenes.

1988 • 72 citations

An activated c-Ha-ras allele blocks the induction of muscle-specific genes whose expression is contingent on mitogen withdrawal.

1987 • 68 citations

Multiple controls for the synthesis of muscle-specific proteins in BC3H1 cells.

1982 • 67 citations

Density‐dependent arrest of DNA replication is accompanied by decreased levels of c‐myc mRNA in myogenic but not in differentiation‐defective myoblasts

1985 • 65 citations

Variation in observed coronal calcium abundance of X-ray flare plasmas

1984 • 65 citations

c-myc Oncogene expression inhibits the initiation of myogenic differentiation

1987 • 60 citations

Complete nucleotide sequence of dog heart creatine kinase mRNA: conservation of amino acid sequence within and among species.

1985 • 56 citations

Growth factors, signaling pathways, and the regulation of proliferation and differentiation in BC3H1 muscle cells. II. Two signaling pathways distinguished by pertussis toxin and a potential role for the ras oncogene.

1989 • 51 citations

Regulation of differentiation of the BC3H1 muscle cell line through cAMP-dependent and -independent pathways.

1988 • 49 citations

Characterization of actin mRNA levels during BC3H1 cell differentiation.

1986 • 43 citations

Manipulation of medium conditions and differentiation in the rat myogenic cell line L6

1984 • 43 citations

Expression of differentiated functions in heterokaryons between skeletal myocytes, adrenal cells, fibroblasts and glial cells

1984 • 42 citations

Inhibition of myogenic differentiation by fibroblast growth factor or type β transforming growth factor does not require persistent c-myc expression

1987 • 42 citations

A ras-dependent pathway abolishes activity of a muscle-specific enhancer upstream from the muscle creatine kinase gene.

1989 • 39 citations

The suppression of myogenic functions in heterokaryons formed by fusing chick myocytes to diploid rat fibroblasts

1983 • 21 citations

Messengers coding for myosins and actins their accumulation during terminal differentiation of a mouse muscle cell line

1982 • 3 citations