A critical role for NF-κB in Gata3 expression and TH2 differentiation in allergic airway inflammation

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

2000 • 3,456 citations

Predominant T_H2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

1992 • 2,802 citations

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

1997 • 2,317 citations

Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

1995 • 1,184 citations

IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESS

1999 • 1,047 citations

Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence

1995 • 923 citations

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

1998 • 800 citations

Allergic and Nonallergic Asthmatics Have Distinct Patterns of T-Cell Activation and Cytokine Production in Peripheral Blood and Bronchoalveolar Lavage

1992 • 788 citations

IGIF Does Not Drive Th1 Development but Synergizes with IL-12 for Interferon-γ Production and Activates IRAK and NFκB

1997 • 726 citations

Stat6-Independent GATA-3 Autoactivation Directs IL-4-Independent Th2 Development and Commitment

2000 • 697 citations

Modulation of Chromatin Structure Regulates Cytokine Gene Expression during T Cell Differentiation

1998 • 697 citations

Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene

1997 • 666 citations

Transcription factor GATA-3 is required for development of the T-cell lineage

1996 • 614 citations

The transcription factor NF-ATc is essential for cardiac valve formation

1998 • 580 citations

Transcriptional regulation of the IL-2 gene

1995 • 579 citations

Regulation of Interleukin 12 p40 Expression through an NF-κB Half-Site

1995 • 495 citations

Induction of Airway Mucus Production By T Helper 2 (Th2) Cells: A Critical Role For Interleukin 4 In Cell Recruitment But Not Mucus Production

1997 • 464 citations

Interaction of NF-κB and NFAT with the Interferon-γ Promoter

1997 • 427 citations

The Transcription Factor NF-ATc1 Regulates Lymphocyte Proliferation and Th2 Cytokine Production

1998 • 340 citations

Inhibition of Allergic Inflammation in a Murine Model of Asthma by Expression of a Dominant-Negative Mutant of GATA-3

1999 • 333 citations

NF-κB Subunit Regulation in Nontransformed CD4 ⁺ T Lymphocytes

1992 • 322 citations

Essential Role of Nuclear Factor κB in the Induction of Eosinophilia in Allergic Airway Inflammation

1998 • 304 citations

IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells.

1998 • 296 citations

TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION

1999 • 293 citations

Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation

1999 • 285 citations

Requirements for Interleukin-4-Induced Gene Expression and Functional Characterization of Stat6

1996 • 279 citations

Cell-Type-Restricted Binding of the Transcription Factor NFAT to a Distal IL-4 Enhancer In Vivo

2000 • 270 citations

Cutting Edge: IL-4-Independent Induction of Airway Hyperresponsiveness by Th2, But Not Th1, Cells

1998 • 234 citations

Embryonic expression and cloning of the murine GATA-3 gene

1994 • 233 citations

Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3.

1998 • 228 citations

GATA-3-dependent enhancer activity in IL-4 gene regulation.

1998 • 205 citations

Interaction of Stat6 and NF-κB: Direct Association and Synergistic Activation of Interleukin-4-Induced Transcription

1998 • 202 citations

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50.

1995 • 201 citations

Regulation of Immune Responses by NF-κB/Rel Transcription Factors

1998 • 193 citations

Interleukin-18 Activates NF-κB in Murine T Helper Type 1 Cells

1997 • 192 citations

Structural comparison and chromosomal localization of the human and mouse IL-13 genes.

1993 • 167 citations

Cutting Edge: Differential Responsiveness of the IL-5 and IL-4 Genes to Transcription Factor GATA-3

1998 • 162 citations

Cutting Edge: GATA-3-Dependent Enhancer Activity in IL-4 Gene Regulation

1998 • 158 citations

Activation of the Interleukin-5 Promoter by cAMP in Murine EL-4 Cells Requires the GATA-3 and CLE0 Elements

1995 • 137 citations

Physiologic activation of T cells via the T cell receptor induces NF-kappa B.

1991 • 95 citations

Tumor Necrosis Factor-α-induced Proliferation of Human Mo7e Leukemic Cells Occurs via Activation of Nuclear Factor κB Transcription Factor

1999 • 27 citations