Interaction of Stat6 and NF-κB: Direct Association and Synergistic Activation of Interleukin-4-Induced Transcription

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

STATs: Signal Transducers and Activators of Transcription

1996 • 1,414 citations

An Interleukin-4-Induced Transcription Factor: IL-4 Stat

1994 • 856 citations

The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.

1991 • 805 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

1993 • 639 citations

Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction.

1993 • 530 citations

Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression.

1986 • 516 citations

Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α

1996 • 492 citations

Two contact regions between Stat1 and CBP/p300 in interferon γ signaling

1996 • 486 citations

Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations.

1992 • 461 citations

Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity.

1995 • 423 citations

Synergy between Interferon-γ and Tumor Necrosis Factor-α in Transcriptional Activation Is Mediated by Cooperation between Signal Transducer and Activator of Transcription 1 and Nuclear Factor κB

1997 • 410 citations

Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3.

1995 • 363 citations

Antibody Class Switching

1996 • 327 citations

In vivo control of NF-kappa B activation by I kappa B alpha.

1993 • 326 citations

Cloning of Murine Stat6 and Human Stat6, Stat Proteins That Are Tyrosine Phosphorylated in Responses to IL-4 and IL-3 but Are Not Required for Mitogenesis

1995 • 325 citations

The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor.

1992 • 324 citations

Requirements for Interleukin-4-Induced Gene Expression and Functional Characterization of Stat6

1996 • 279 citations

REL/NF-κB/IκB Story

1995 • 278 citations

Components of a stat recognition code: Evidence for two layers of molecular selectivity

1995 • 254 citations

Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3.

1995 • 231 citations

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50.

1995 • 201 citations

Formation of STAT1-STAT2 Heterodimers and Their Role in the Activation of IRF-1 Gene Transcription by Interferon-α

1996 • 196 citations

Cyclic AMP-independent ATF family members interact with NF-kappa B and function in the activation of the E-selectin promoter in response to cytokines.

1993 • 191 citations

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction.

1997 • 136 citations

Multiple Protein-Binding Sites in the 5′-Flanking Region Regulate c-fos Expression

1986 • 133 citations

Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation.

1994 • 125 citations

Induction of germ-line gamma 1 and epsilon Ig gene expression in murine B cells. IL-4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals.

1995 • 113 citations

Functional and Physical Associations between NF-κB and C/EBP Family Members: a Rel Domain-bZIP Interaction

1993 • 112 citations

Cooperation of binding sites for STAT6 and NF kappa B/rel in the IL-4-induced up-regulation of the human IgE germline promoter.

1997 • 107 citations

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene.

1991 • 103 citations

Functional Interaction of the v-Rel and c-Rel Oncoproteins with the TATA-Binding Protein and Association with Transcription Factor IIB

1993 • 102 citations

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes.

1985 • 99 citations

Activation of NF-κB/Rel by CD40 Engagement Induces the Mouse Germ Line Immunoglobulin Cγ1 Promoter

1996 • 85 citations

One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs.

1994 • 57 citations

Analysis of the promoter elements necessary for IL-4 and anti-CD40 antibody induction of murine Fc epsilon RII (CD23): comparison with the germline epsilon promoter.

1997 • 41 citations

Independent pathways for de-repression of the mouse Ig heavy chain germ-line ε promoter: an IL-4 NAF/NF-IL-4 site as a context-dependent negative element

1996 • 21 citations

One Exon of the Human LSF Gene Includes Conserved Regions Involved in Novel DNA-Binding and Dimerization Motifs

1994 • 21 citations