Biogenesis of eukaryotic 20S proteasomes: the complex maturation pathway of a complex enzyme

STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

1996 • 2,408 citations

Structure of 20S proteasome from yeast at 2.4Å resolution

1997 • 2,211 citations

Crystal Structure of the 20 S Proteasome from the Archaeon T. acidophilum at 3.4 Å Resolution

1995 • 1,513 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

The crystal structure of the bacterial chaperonln GroEL at 2.8 Å

1994 • 1,322 citations

A protein catalytic framework with an N-terminal nucleophile is capable of self-activation

1995 • 609 citations

The Active Sites of the Eukaryotic 20 S Proteasome and Their Involvement in Subunit Precursor Processing

1997 • 506 citations

Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival.

1991 • 421 citations

Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly

1996 • 390 citations

Proteasomes: destruction as a programme

1996 • 373 citations

Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids

1993 • 323 citations

The multicatalytic proteinase (prosome) is ubiquitous from eukaryotes to archaebacteria

1989 • 277 citations

Identification, purification, and characterization of a high molecular weight, ATP-dependent activator (PA700) of the 20 S proteasome.

1994 • 238 citations

Autocatalytic processing of the 20S proteasome

1996 • 226 citations

Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.

1994 • 220 citations

Critical elements in proteasome assembly

1994 • 203 citations

Conformational constraints in protein degradation by the 20S proteasome

1995 • 202 citations

Processive Degradation of Proteins and Other Catalytic Properties of the Proteasome from Thermoplasma acidophilum

1997 • 200 citations

Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit.

1996 • 196 citations

Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma.

1996 • 195 citations

In Vivo Assembly of the Proteasomal Complexes, Implications for Antigen Processing

1995 • 193 citations

Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis.

1996 • 191 citations

Symmetric Complexes of GroE Chaperonins as Part of the Functional Cycle

1994 • 190 citations

The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus

1995 • 186 citations

Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits

1997 • 181 citations

Existence of a molecular ruler in proteasomes suggested by analysis of degradation products

1994 • 179 citations

A third interferon‐γ‐induced subunit exchange in the 20S proteasome

1996 • 168 citations

Incorporation of major histocompatibility complex – encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon‐γ

1995 • 167 citations

20 S proteasomes are assembled via distinct precursor complexes processing of LMP2 and LMP7 proproteins takes place in 13–16 S preproteasome complexes

1994 • 146 citations

New insights into the mechanisms and importance of the proteasome in intracellular protein degradation.

1997 • 140 citations

Localization of subunits in proteasomes from Thermoplasma acidophilum by immunoelectron microscopy

1991 • 123 citations

PRE5 and PRE6, the Last Missing Genes Encoding 20S Proteasome Subunits from Yeast? Indication for a Set of 14 Different Subunits in the Eukaryotic Proteasome Core

1994 • 121 citations

Subunit arrangement in the human 20S proteasome

1997 • 121 citations

Biogenesis, structure and function of the yeast 20S proteasome.

1995 • 115 citations

Degradation of oxidized insulin B chain by the multiproteinase complex macropain (proteasome)

1991 • 99 citations

Evidence Indicating that the Human Proteasome is a Complex Dimer

1993 • 97 citations

Human proteasomes analysed with monoclonal antibodies

1995 • 91 citations

The Human α-Type Proteasomal Subunit HsC8 Forms a Double Ringlike Structure, but Does Not Assemble into Proteasome-like Particles with the β-Type Subunits HsDelta or HsBPROS26

1997 • 89 citations

Folding pathway mediated by an intramolecular chaperone.

1993 • 84 citations

Biochemical properties of the proteasome from Thermoplasma acidophilum

1992 • 78 citations

Proteasomes of the yeastS. cerevisiae: genes, structure and functions

1995 • 73 citations

A Proteasome from the Methanogenic Archaeon Methanosarcina thermophila

1995 • 70 citations

N‐Terminal sequence similarities between components of the multicatalytic proteinase complex

1990 • 56 citations

The Proteasome Subunit, C2, Contains an Important Site for Binding of the PA28 (11S) Activator

1996 • 50 citations

The Structural and Functional Organization of Intramolecular Chaperones: The N-Terminal Propeptides Which Mediate Protein Folding1

1994 • 47 citations

The 26S proteasome: a dynamic structure.

1997 • 28 citations

Proteasome: a complex protease with a new fold and a distinct mechanism

1995 • 20 citations

Delineation of the subunit composition of human proteasomes using antisera against the major histocompatibility complex-encoded LMP2 and LMP7 subunits.

1994 • 20 citations

Structure and structure formation of the 20S proteasome.

1997 • 18 citations

cDNA cloning of a new type of subunit of mammalian proteasomes

1993 • 17 citations

Biochemical properties of insect and crustacean proteasomes.

1997 • 17 citations

Drosophila proteasome Dm25 subunit substitutes the mouse MC3 subunit in hybrid proteasomes. The N-terminal domain is essential for subunit incorporation.

1993 • 14 citations

Cloning and characterization of mouse Lmp3 cDNA, encoding a proteasome β subunit

1997 • 12 citations

The multicatalytic proteinase (prosome, proteasome): comparison of the eukaryotic and archaebacterial enzyme.

1991 • 12 citations