Folding pathway mediated by an intramolecular chaperone.

Protein folding in the cell

1992 • 4,138 citations

Computed circular dichroism spectra for the evaluation of protein conformation

1969 • 3,654 citations

Mammalian subtilisins: The long-sought dibasic processing endoproteases

1991 • 756 citations

Structure of Subtilisin BPN′ at 2.5 Å Resolution

1969 • 543 citations

Pro-sequence of subtilisin can guide the refolding of denatured subtilisin in an intermolecular process

1989 • 345 citations

Requirement of pro-sequence for the production of active subtilisin E in Escherichia coli.

1987 • 326 citations

A protein-folding reaction under kinetic control

1992 • 284 citations

Propeptide of carboxypeptidase Y provides a chaperone-like function as well as inhibition of the enzymatic activity.

1991 • 173 citations

Structural and functional role of leucine residues in proteins

1973 • 135 citations

The pro region of BPTI facilitates folding

1992 • 123 citations

Folding of subtilisin BPN': characterization of a folding intermediate

1993 • 118 citations

Pro‐peptide as an intermolecular chaperone: renaturation of denatured subtilisin E with a synthetic pro‐peptide

1991 • 114 citations

Subtilisin Novo. The Three-Dimensional Structure and Its Comparison with Subtilisin BPN'

1972 • 104 citations

The refined crystal structure of subtilisin Carlsberg at 2.5 Å resolution

1988 • 100 citations

Intramolecular Chaperone: The Role of the Pro-Peptide in Protein Folding

1991 • 96 citations

Energetics of folding subtilisin BPN'

1992 • 96 citations

Intracellular serine protease of Bacillus subtilis: sequence homology with extracellular subtilisins

1978 • 90 citations

Functional analysis of the intramolecular chaperone

1992 • 44 citations

Pro‐subtilisin E: purification and characterization of its autoprocessing to active subtilisin E in vitro

1990 • 32 citations