Cloning and characterization of mouse Lmp3 cDNA, encoding a proteasome β subunit

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1994 • 2,480 citations

The ubiquitin-proteasome proteolytic pathway

1994 • 1,778 citations

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

1995 • 1,601 citations

Crystal Structure of the 20 S Proteasome from the Archaeon T. acidophilum at 3.4 Å Resolution

1995 • 1,513 citations

Proteasomes: multicatalytic proteinase complexes

1993 • 395 citations

Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly

1996 • 390 citations

Interferon-γ Induces Different Subunit Organizations and Functional Diversity of Proteasomes1

1994 • 371 citations

Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes

1991 • 310 citations

Autocatalytic processing of the 20S proteasome

1996 • 226 citations

Critical elements in proteasome assembly

1994 • 203 citations

Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit.

1996 • 196 citations

Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma.

1996 • 195 citations

In Vivo Assembly of the Proteasomal Complexes, Implications for Antigen Processing

1995 • 193 citations

Proteolytic processing of ovalbumin and beta-galactosidase by the proteasome to a yield antigenic peptides.

1994 • 172 citations

Proteolytic processing of ovalbumin and beta-galactosidase by the proteasome to a yield antigenic peptides.

1994 • 160 citations

The PRE4 gene codes for a subunit of the yeast proteasome necessary for peptidylglutamyl-peptide-hydrolyzing activity. Mutations link the proteasome to stress- and ubiquitin-dependent proteolysis.

1993 • 149 citations

20 S proteasomes are assembled via distinct precursor complexes processing of LMP2 and LMP7 proproteins takes place in 13–16 S preproteasome complexes

1994 • 146 citations

Proteasomes: protein and gene structures.

1992 • 108 citations

THE GENETICS OF PROTEASOMES AND ANTIGEN PROCESSING

1995 • 108 citations

N‐Terminal sequence similarities between components of the multicatalytic proteinase complex

1990 • 56 citations

MHC-linked low-molecular mass polypeptide subunits define distinct subsets of proteasomes. Implications for divergent function among distinct proteasome subsets.

1993 • 53 citations

Newly Identified Pair of Proteasomal Subunits Regulated Reciprocally by Interferon γ

1997 • 39 citations

Processing of N3, a mammalian proteasome β-type subunit

1996 • 28 citations

cDNA cloning of a new type of subunit of mammalian proteasomes

1993 • 17 citations

Post-translational processing of a major histocompatibility complex-encoded proteasome subunit, LMP-2

1993 • 13 citations