A third interferon‐γ‐induced subunit exchange in the 20S proteasome

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

1995 • 1,601 citations

Crystal Structure of the 20 S Proteasome from the Archaeon T. acidophilum at 3.4 Å Resolution

1995 • 1,513 citations

In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis

1992 • 1,259 citations

Peptides Naturally Presented by MHC Class I Molecules

1993 • 803 citations

γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

1993 • 572 citations

MHC Class I Expression in Mice Lacking the Proteasome Subunit LMP-7

1994 • 520 citations

The multicatalytic and 26 S proteases.

1993 • 476 citations

MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

1993 • 453 citations

Altered peptidase and viral-specific T cell response in LMP2 mutant mice

1994 • 450 citations

Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain).

1992 • 439 citations

A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC

1991 • 427 citations

Purification of an 11 S regulator of the multicatalytic protease.

1992 • 384 citations

Second proteasome-related gene in the human MHC class II region

1991 • 348 citations

Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes.

1994 • 314 citations

The multicatalytic proteinase (prosome) is ubiquitous from eukaryotes to archaebacteria

1989 • 277 citations

Subunit of the '20S' proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex

1991 • 262 citations

Selective protein degradation: A journey's end within the proteasome

1995 • 259 citations

Homology of proteasome subunits to a major histocompatibility complex-linked LMP gene

1991 • 256 citations

Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase

1992 • 235 citations

The Interferon-γ-inducible 11 S Regulator (PA28) and the LMP2/LMP7 Subunits Govern the Peptide Production by the 20 S Proteasome in Vitro

1995 • 233 citations

Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules

1995 • 225 citations

Conformational constraints in protein degradation by the 20S proteasome

1995 • 202 citations

Primary structures of two homologous subunits of PA28, a γ‐interferon‐inducible protein activator of the 20S proteasome

1995 • 196 citations

The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus

1995 • 186 citations

cDNA Cloning and Interferon γ Down-Regulation of Proteasomal Aubunits X and Y

1994 • 181 citations

Existence of a molecular ruler in proteasomes suggested by analysis of degradation products

1994 • 179 citations

Proteolytic processing of ovalbumin and beta-galactosidase by the proteasome to a yield antigenic peptides.

1994 • 172 citations

Incorporation of major histocompatibility complex – encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon‐γ

1995 • 167 citations

Proteolytic processing of ovalbumin and beta-galactosidase by the proteasome to a yield antigenic peptides.

1994 • 160 citations

Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins

1994 • 157 citations

20 S proteasomes are assembled via distinct precursor complexes processing of LMP2 and LMP7 proproteins takes place in 13–16 S preproteasome complexes

1994 • 146 citations

Genes encoded in the major histocompatibility complex affecting the generation of peptides for TAP transport

1995 • 129 citations

Alternative exon usage and processing of the major histocompatibility complex-encoded proteasome subunits.

1992 • 119 citations

Molecular cloning of cDNA for proteasomes (multicatalytic proteinase complexes) from rat liver: primary structure of the largest component (C2)

1989 • 86 citations

A tight cluster of five unrelated human genes on chromosome 16q22.1

1993 • 83 citations

Effects of interferon gamma and major histocompatibility complex-encoded subunits on peptidase activities of human multicatalytic proteases.

1995 • 80 citations

Molecular Structures of 20S and 26S Proteasomes

1993 • 79 citations

Proteasomes of the yeastS. cerevisiae: genes, structure and functions

1995 • 73 citations

cDNA cloning and sequencing of component C9 of proteasomes from rat hepatoma cells

1990 • 67 citations

Relationships among the subunits of the high molecular weight proteinase, macropain (proteasome)

1990 • 67 citations

The major‐histocompatibility‐complex‐encoded β‐type proteasome subunits LMP2 and LMP7

1993 • 61 citations

N‐Terminal sequence similarities between components of the multicatalytic proteinase complex

1990 • 56 citations

The proteasome from Thermoplasma acidophilum is neither a cysteine nor a serine protease

1995 • 51 citations

cDNA cloning and sequencing of component C8 of proteasomes from rat hepatoma cells

1990 • 50 citations

The human proteasome subunit HsN3 is located inthe inner rings of the complex dimer

1995 • 50 citations

cDNA cloning and sequencing of component C5 of proteasomes from rat hepatoma cells

1990 • 48 citations

Nucleotide sequence ofPUP1encoding a putative proteasome subunit inSaccharomyces cerevisiae

1991 • 33 citations

Molecular Cloning of cDNAs for Rat Proteasomes: Deduced Primary Structures of Four Other Subunits1

1992 • 30 citations

Isolation and characterization of the MHC linked β‐type proteasome subunit MC13 cDNA

1992 • 29 citations

Archaebacterial and eukaryotic proteasomes prefer different sites in cleaving gonadotropin-releasing hormone

1995 • 21 citations

Characterization of Mouse Proteasome Subunit MC3 and Identification of Proteasome Subtypes with Different Cleavage Characteristics

1993 • 19 citations

cDNA cloning of a new type of subunit of mammalian proteasomes

1993 • 17 citations

cDNA cloning of rat proteasome subunit RC10‐II, assumed to be responsible for trypsin‐like catalytic activity

1993 • 16 citations

Molecular cloning of two types of cDNA encoding subunit RC6-I of rat proteasomes

1995 • 16 citations

cDNA cloning of rat proteasome subunit RC7‐I, a homologue of yeast PRE1 essential for chymotrypsin‐like activity

1993 • 12 citations